Disease · MONDO_0019019
Trials28
Trials an Open Targets clinical report links to the disease, posted results first, then the largest. A trial is shown when the release's checks confirm its link to the disease and Drugs and targets shows its link to one of the disease's drugs.
1 to 20 of 28
Download this page as JSON| Trial | Title | Phase | Participants | Results first posted | Conditions | Drugs | Linked by | Source |
|---|---|---|---|---|---|---|---|---|
| NCT02352753 | Multicenter,Single-arm Study to Evaluate Efficacy, Safety, & Pharmacokinetics of Denosumab in Children w/ OI | Phase 3 | 153 | 2022-12-28 | Osteogenesis Imperfecta | DENOSUMAB | Its record names the disease | ClinicalTrials.gov |
| NCT00106028 | Safety and Efficacy of Risedronate in the Treatment of Osteogenesis Imperfecta in Children | Phase 3 | 143 | 2010-06-28 | Osteogenesis Imperfecta | RISEDRONIC ACID | Its record names the disease | ClinicalTrials.gov |
| NCT03118570 | A Study in Adult Patients With Type I, III or IV Osteogenesis Imperfecta Treated With BPS804 | Phase 2 | 112 | 2022-03-02 | Osteogenesis Imperfecta, Type I, Osteogenesis Imperfecta Type III, Osteogenesis Imperfecta Type IV | SETRUSUMAB | Its record names the disease | ClinicalTrials.gov |
| NCT00131469 | Study of Teriparatide (FORTEO) to Treat Adults With Osteogenesis Imperfecta | Phase 4 | 79 | 2019-04-24 | Osteogenesis Imperfecta | TERIPARATIDE | Its record names the disease | ClinicalTrials.gov |
| NCT03638128 | Open-label Extension of Study 20130173 of Denosumab in Children and Young Adults With Osteogenesis Imperfecta | Phase 3 | 75 | 2022-12-20 | Osteogenesis Imperfecta (OI) | DENOSUMAB | Its record names the disease | ClinicalTrials.gov |
| NCT00001305 | Growth Hormone Therapy in Osteogenesis Imperfecta | Phase 3 | 42 | 2019-01-29 | Osteogenesis Imperfecta | SOMATROPIN | Its record names the disease | ClinicalTrials.gov |
| NCT00005901 | Pamidronate to Treat Osteogenesis Imperfecta in Children | Phase 3 | 34 | 2016-03-01 | Osteogenesis Imperfecta | PAMIDRONIC ACID, SOMATROPIN | Its record names the disease | ClinicalTrials.gov |
| NCT04545554 | Study to Evaluate Romosozumab in Children and Adolescents With Osteogenesis Imperfecta | Phase 1 | 25 | 2024-04-15 | Osteogenesis Imperfecta | ROMOSOZUMAB | Its record names the disease | ClinicalTrials.gov |
| NCT03064074 | Safety of Fresolimumab in the Treatment of Osteogenesis Imperfecta | Phase 1 | 11 | 2024-10-08 | Osteogenesis Imperfecta | FRESOLIMUMAB | Its record names the disease | ClinicalTrials.gov |
| NCT05312697 | Long-term Extension Study of Setrusumab in Adults With Type I, III, or IV Osteogenesis Imperfecta | Phase 2 | 2 | 2025-07-23 | Osteogenesis Imperfecta | SETRUSUMAB | Its record names the disease | ClinicalTrials.gov |
| NCT05125809 | Setrusumab vs Placebo for Osteogenesis Imperfecta | Phase 2/3 | 183 | Osteogenesis Imperfecta | SETRUSUMAB | Its record names the disease | ClinicalTrials.gov | |
| NCT00063479 | Bisphosphonate Treatment of Osteogenesis Imperfecta | Phase 2 | 158 | Osteogenesis Imperfecta | ZOLEDRONIC ACID | Its record names the disease | ClinicalTrials.gov | |
| NCT00131118 | Zoledronic Acid in Children (1 -17 Years) With Severe Osteogenesis Imperfecta | Phase 2 | 127 | Osteogenesis Imperfecta | ZOLEDRONIC ACID | Its record names the disease | ClinicalTrials.gov | |
| NCT05972551 | Study to Evaluate Efficacy and Safety of Romosozumab Compared With Bisphosphonates in Children and Adolescents With Osteogenesis Imperfecta | Phase 3 | 111 | Osteogenesis Imperfecta | ROMOSOZUMAB | Its record names the disease | ClinicalTrials.gov | |
| NCT05768854 | Setrusumab vs Bisphosphonates in Pediatric Subjects With Osteogenesis Imperfecta | Phase 3 | 69 | Osteogenesis Imperfecta | SETRUSUMAB | Its record names the disease | ClinicalTrials.gov | |
| NCT03169192 | Diagnosis of Osteogenesis Imperfecta in Children | 40 | Bone Disease, Metabolic | ZOLEDRONIC ACID | Its record names the disease | ClinicalTrials.gov | ||
| NCT00757393 | Growth Hormone Therapy and Bone Quality in Pediatric Osteoporosis | Phase 3 | 21 | Osteoporosis | CALCIUM, ERGOCALCIFEROL, SOMATROPIN | Its record names the disease | ClinicalTrials.gov | |
| NCT05321199 | Tranexamic Acid During Telescoping Nail Application In Osteogenesis Imperfecta | Not applicable | 20 | Osteogenesis Imperfecta | TRANEXAMIC ACID | Its record names the disease | ClinicalTrials.gov | |
| NCT05231668 | Single Ascending Dose Study of SAR439459 in Adults With Osteogenesis Imperfecta (OI) | Phase 1 | 16 | Osteogenesis Imperfecta | SAR-439459 | Its record names the disease | ClinicalTrials.gov | |
| NCT00982124 | An Efficacy and Safety Trial of Intravenous Zoledronic Acid in Infants Less Than One Year of Age, With Severe Osteogenesis Imperfecta | Phase 3 | 14 | Osteogenesis Imperfecta | PAMIDRONIC ACID, ZOLEDRONIC ACID | Its record names the disease | ClinicalTrials.gov |
diseases-2026-09-18-0.1.0
Sources 6
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- NLM's MeSHNLM's terms
- Open TargetsCC0 1.0
- PubMedNLM's terms
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- NLM's MeSHNLM's
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this list from software.
Twenty rows a page, as JSON. No key.
GET https://conductscience.org/api/diseases/v1/MONDO_0019019/trials