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Disease · MONDO_0019313

Trials11

Trials an Open Targets clinical report links to the disease, posted results first, then the largest. A trial is shown when the release's checks confirm its link to the disease and Drugs and targets shows its link to one of the disease's drugs.

TrialTitlePhaseParticipantsResults first postedConditionsDrugsLinked bySource
NCT02335242Sildenafil for the Treatment of Lymphatic MalformationsPhase 2222022-11-17Lymphatic Malformations, Lymphatic DiseasesSILDENAFILOpen Targets' reading of its recordClinicalTrials.gov
NCT01290484A Study to Evaluate Sildenafil for the Treatment of Lymphatic MalformationsPhase 1/272014-06-12LymphangiomaSILDENAFILOpen Targets' reading of its recordClinicalTrials.gov
NCT06943703Bleomycin as an Effective and Curative Adjunct Therapy for Lymphangioma809Lymphangioma, Lymphatic MalformationsBLEOMYCINOpen Targets' reading of its recordClinicalTrials.gov
NCT05948943Alpelisib in Pediatric and Adult Patients With Lymphatic Malformations Associated With a PIK3CA Mutation.Phase 2/3232Lymphatic MalformationsALPELISIBOpen Targets' reading of its recordClinicalTrials.gov
NCT06437158Use of Bleomycin in the Sclerotherapy of Lymphatic Malformations for Pediatric PatientsPhase 2200Lymphatic MalformationBLEOMYCINIts record names the diseaseClinicalTrials.gov
NCT07579962Treatment of Low-flow Vascular Malformations With Bleomycin Electrosclerotherapy (BEST)Phase 2140Vascular MalformationsBLEOMYCINIts record names the diseaseClinicalTrials.gov
NCT07320001Injection Sclerotherapy With Bleomycin VS Doxycycline in Patients With Lymphatic MalformationsPhase 292Lymphatic AbnormalityBLEOMYCIN, DOXYCYCLINEOpen Targets' reading of its recordClinicalTrials.gov
NCT03243019Efficacy of Rapamycin in the Treatment of Cervico-facial Lymphatic MalformationsPhase 228Lymphatic Malformation, PediatricSIROLIMUSIts record names the diseaseClinicalTrials.gov
NCT04861064Weekly Sirolimus TherapyPhase 224Venous Malformation, Lymphatic MalformationSIROLIMUSIts record names the diseaseClinicalTrials.gov
NCT04128722TOPical Sirolimus in linGUal Microcystic Lymphatic Malformation -TOPGUNPhase 212Lingual Microcystic Lymphatic MalformationsSIROLIMUSOpen Targets' reading of its recordClinicalTrials.gov
NCT01212965Selenium in the Treatment of Complicated Lymphatic MalformationsPhase 15Lymphatic MalformationsSELENIUMOpen Targets' reading of its recordClinicalTrials.gov

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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