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Disease · MONDO_0019434

Comparisons in its trials31

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
ACZ885 Treatment Naive vs ACZ885 Treated: Number of Participants With Anti -ACZ885 Antibodies at Any Visit During the Study0 of 1230 of 147270NCT00891046Trial comparisons
ACZ885 Treated vs ACZ885 Treatment Naive: serious adverse events47 of 14740 of 123270NCT00891046Trial comparisons
Canakinumab vs Placebo: serious adverse events2 of 432 of 4184NCT00886769Trial comparisons
Anakinra vs Placebo: Proportion of Patients With Macrophage Activation Syndrome (MAS).0 of 60 of 612NCT03265132Trial comparisons
Anakinra vs Placebo: Proportion of Patients With Antidrug Antibodies (ADA) Against Anakinra.6 of 61 of 612NCT03265132Trial comparisons
Anakinra vs Placebo: Proportion of Patients With Neutralizing Antibodies.0 of 60 of 612NCT03265132Trial comparisons
Anakinra vs Placebo: Proportion of Patients With at Least One Serious Adverse Event Including Death.0 of 61 of 612NCT03265132Trial comparisons
Anakinra vs Placebo: Proportion of Patients With at Least One Adverse Event.6 of 64 of 612NCT03265132Trial comparisons
Anakinra vs Placebo: deaths from any cause0 of 60 of 612NCT03265132Trial comparisons
Anakinra vs Placebo: serious adverse events0 of 61 of 612NCT03265132Trial comparisons
Anakinra vs Placebo: Proportion of Responders in Assessment of Physical Function (CHAQ/SHAQ).4 of 60 of 511NCT03265132Trial comparisons
Anakinra vs Placebo: Proportion of ACR70 Responders With Absence of Fever During 24 Hours Preceding Week 1.5 of 60 of 511NCT03265132Trial comparisons
Anakinra vs Placebo: Proportion of ACR90 Responders With Absence of Fever During 24 Hours Preceding Week 1.4 of 60 of 511NCT03265132Trial comparisons
Anakinra vs Placebo: Proportion of ACR50 Responders With Absence of Fever During 7 Days Preceding Week 2.6 of 60 of 511NCT03265132Trial comparisons
Anakinra vs Placebo: Proportion of ACR30 Responders With Absence of Fever Attributable to the Disease During the 7 Days Preceding Week 2.6 of 60 of 511NCT03265132Trial comparisons
Anakinra vs Placebo: Proportion of Patients With Inactive Disease.3 of 60 of 511NCT03265132Trial comparisons
Anakinra vs Placebo: Proportion of ACR70 Responders With Absence of Fever During 7 Days Preceding Week 2.6 of 60 of 511NCT03265132Trial comparisons
Anakinra vs Placebo: Proportion of Patients With Absence of Fever During the 24 Hours Preceding Week 1.6 of 64 of 511NCT03265132Trial comparisons
Anakinra vs Placebo: Proportion of ACR30 Responders With Absence of Fever During 24 Hours Preceding Week 1.5 of 63 of 511NCT03265132Trial comparisons
Anakinra vs Placebo: Proportion of Patients With Absence of Fever During the 7 Days Preceding Week 2.6 of 60 of 511NCT03265132Trial comparisons

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this list from software.

Twenty rows a page, as JSON. No key.

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