Disease · MONDO_0021063
Trials220
Trials an Open Targets clinical report links to the disease, posted results first, then the largest. A trial is shown when the release's checks confirm its link to the disease and Drugs and targets shows its link to one of the disease's drugs. 14 more are not shown, since the checks do not confirm them.
1 to 20 of 220
Download this page as JSON| Trial | Title | Phase | Participants | Results first posted | Conditions | Drugs | Linked by | Source |
|---|---|---|---|---|---|---|---|---|
| NCT00079274 | Comparison of Combination Chemotherapy Regimens With or Without Cetuximab in Treating Patients Who Have Undergone Surgery For Stage III Colon Cancer | Phase 3 | 3,397 | 2015-02-09 | Adenocarcinoma of the Colon, Stage III Colon Cancer | CETUXIMAB, FLUOROURACIL, IRINOTECAN HYDROCHLORIDE, LEUCOVORIN CALCIUM, OXALIPLATIN | Its record names the disease | ClinicalTrials.gov |
| NCT01150045 | Oxaliplatin, Leucovorin Calcium, and Fluorouracil With or Without Celecoxib in Treating Patients With Stage III Colon Cancer Previously Treated With Surgery | Phase 3 | 2,527 | 2021-08-06 | Colorectal Cancer | CELECOXIB, FLUOROURACIL, LEUCOVORIN CALCIUM, OXALIPLATIN | Its record names the disease | ClinicalTrials.gov |
| NCT00217737 | Oxaliplatin, Leucovorin, and Fluorouracil With or Without Bevacizumab in Treating Patients Who Have Undergone Surgery for Stage II Colon Cancer | Phase 3 | 2,431 | 2025-07-20 | Colon Adenocarcinoma, Stage IIA Colon Cancer AJCC v7, Stage IIB Colon Cancer AJCC v7, Stage IIC Colon Cancer AJCC v7 | BEVACIZUMAB, FLUOROURACIL, LEUCOVORIN, OXALIPLATIN | Its record names the disease | ClinicalTrials.gov |
| NCT00009737 | A Study of Xeloda (Capecitabine) Compared With 5-Fluorouracil in Combination With Low-Dose Leucovorin in Patients Who Have Undergone Surgery for Colon Cancer | Phase 3 | 1,987 | 2016-06-22 | Colorectal Cancer | CAPECITABINE, FLUOROURACIL, LEUCOVORIN CALCIUM | Its record names the disease | ClinicalTrials.gov |
| NCT00069121 | A Study of Xeloda (Capecitabine) Plus Oxaliplatin in Patients With Colon Cancer | Phase 3 | 1,886 | 2011-07-29 | Colorectal Cancer | CAPECITABINE, FLUOROURACIL, LEUCOVORIN, OXALIPLATIN | Its record names the disease | ClinicalTrials.gov |
| NCT00002525 | Perioperative Chemotherapy in Treating Patients With Colon Cancer That Can Be Surgically Removed | Phase 3 | 859 | 2016-07-20 | Colorectal Cancer | FLUOROURACIL, LEUCOVORIN CALCIUM | Its record names the disease | ClinicalTrials.gov |
| NCT04068103 | Circulating Tumor DNA Testing in Predicting Treatment for Patients With Stage IIA Colon Cancer After Surgery | Phase 2/3 | 635 | 2025-04-27 | Colon Adenocarcinoma, Stage IIA Colon Cancer AJCC v8 | CAPECITABINE, FLUOROURACIL, LEUCOVORIN CALCIUM, OXALIPLATIN | Its record names the disease | ClinicalTrials.gov |
| NCT01664494 | An Observational Study of Xeloda (Capecitabine) in Patients With Metastatic Colorectal Cancer, Colon Cancer in the Adjuvant Setting, Advanced Gastric Cancer or Breast Cancer | 563 | 2016-05-02 | Breast Cancer, Colorectal Cancer, Gastric Cancer | CAPECITABINE | Its record names the disease | ClinicalTrials.gov | |
| NCT01830621 | BBI608 and Best Supportive Care vs Placebo and Best Supportive Care in Pretreated Advanced Colorectal Carcinoma | Phase 3 | 282 | 2019-03-11 | Colorectal Carcinoma | NAPABUCASIN | Its record names the disease | ClinicalTrials.gov |
| NCT01876511 | Study of MK-3475 in Patients With Microsatellite Unstable (MSI) Tumors (Cohorts A, B and C) | Phase 2 | 113 | 2020-01-07 | MSI Positive Colorectal Cancer, MSI Negative Colorectal Cancer, MSI Positive Non-Colorectal Cancers | PEMBROLIZUMAB | Its record names the disease | ClinicalTrials.gov |
| NCT03058289 | A Phase 1/2 Safety Study of Intratumorally Dosed INT230-6 | Phase 1/2 | 111 | 2024-08-13 | Breast Cancer, Head and Neck Cancer, Squamous Cell Carcinoma, Lymphoma, Pancreatic Cancer, Liver Cancer, Colon Cancer, Lung Cancer, Bile Duct Cancer, Chordoma of Sacrum, Sarcoma | CISPLATIN | Its record names the disease | ClinicalTrials.gov |
| NCT01851369 | TRC102 and Temozolomide for Relapsed Solid Tumors and Lymphomas | Phase 1/2 | 93 | 2024-05-08 | Lymphomas, Solid Tumors, NSCLC, Metastatic Colon Carcinoma, Granulosa Cell Ovarian Cancer | METHOXYAMINE HYDROCHLORIDE, TEMOZOLOMIDE | Its record names the disease | ClinicalTrials.gov |
| NCT00321828 | Combination Chemotherapy and Bevacizumab in Treating Patients With Stage IV Colon Cancer That Cannot Be Removed By Surgery | Phase 2 | 90 | 2013-01-14 | Colorectal Cancer | BEVACIZUMAB, FLUOROURACIL, LEUCOVORIN CALCIUM, OXALIPLATIN | Its record names the disease | ClinicalTrials.gov |
| NCT01442155 | An Observational Study of Adjuvant Treatment With Capecitabine (Xeloda) in Combination With Oxaliplatin in Participants With Stage III Colon Cancer | 74 | 2016-07-07 | Colorectal Cancer | CAPECITABINE, OXALIPLATIN | Its record names the disease | ClinicalTrials.gov | |
| NCT00127036 | Trial for Microarray Analysis of Colon Cancer Outcome-A (MACCO-A) | Phase 2 | 65 | 2012-04-05 | Adenocarcinoma, Colon Cancer | BEVACIZUMAB, CAPECITABINE, IRINOTECAN, OXALIPLATIN | Its record names the disease | ClinicalTrials.gov |
| NCT04625803 | Neoadjuvant Therapy for Locally Advanced Colon Cancer | Phase 2 | 64 | 2025-06-17 | Colon Cancer, Neoadjuvant Therapy | CAMRELIZUMAB, FLUOROURACIL, LEUCOVORIN, OXALIPLATIN, RIVOCERANIB | Its record names the disease | ClinicalTrials.gov |
| NCT01181609 | A Study of Avastin (Bevacizumab) Combined With Chemotherapy in Patients With Metastatic Cancer of the Colon or Rectum | Phase 2 | 54 | 2014-07-28 | Colorectal Cancer | BEVACIZUMAB | Its record names the disease | ClinicalTrials.gov |
| NCT02834052 | Pembrolizumab + Poly-ICLC in MRP Colon Cancer | Phase 1/2 | 42 | 2024-06-07 | Metastatic Colon Cancer, Solid Tumor | HILTONOL, PEMBROLIZUMAB | Its record names the disease | ClinicalTrials.gov |
| NCT01681472 | PK/PD Investigation of Modufolin (Arfolitixorin) in Plasma, Tumor and Adjacent Mucosa Adjacent Mucosa in Patients With Colon Cancer | Phase 1/2 | 32 | 2015-07-17 | Colonic Neoplasms | ARFOLITIXORIN, LEVOLEUCOVORIN | Its record names the disease | ClinicalTrials.gov |
| NCT00888134 | Selumetinib in Cancers With BRAF Mutations | Phase 2 | 28 | 2016-01-15 | Adult Solid Neoplasm | SELUMETINIB | Its record names the disease | ClinicalTrials.gov |
diseases-2026-09-18-0.1.0
Sources 6
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- NLM's MeSHNLM's terms
- Open TargetsCC0 1.0
- PubMedNLM's terms
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- NLM's MeSHNLM's
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this list from software.
Twenty rows a page, as JSON. No key.
GET https://conductscience.org/api/diseases/v1/MONDO_0021063/trials