Drug · CHEMBL161
CEFTRIAXONE
7 sourcespipelines-2026-09-18-0.3.1
Cite this record
ConductScience Library. CEFTRIAXONE. Drugs and targets, record CHEMBL161. Release pipelines-2026-09-18-0.3.1, 18 Sept 2026. https://conductscience.org/library/drugs/CHEMBL161
On this page
Drug
Names and IDs as ChEMBL gives them, through Open Targets.
Targets0
The targets ChEMBL's mechanism records give for the drug, through Open Targets. A mechanism record says what the drug acts on, not how strongly.
None in this release.
Diseases41
The diseases Open Targets' clinical reports study the drug for, the most trial reports first. The stage is Open Targets', the highest any of its sources reports for the pair, and each row names the sources that report it.
1 to 10 of 41Source Open Targets
See all 41 diseasesTrials140
Trials whose record names the drug by a name ChEMBL states, posted results first, then the largest. Open Targets read each trial's text to find its drugs.
| Trial | Title | Phase | Participants | Results first posted | Named as | Linked by | Source |
|---|---|---|---|---|---|---|---|
| NCT02800785 | The Comparison of Outcomes of Antibiotic Drugs and Appendectomy (CODA) Trial | 1,552 | 2023-04-18 | ceftriaxone | Its name | ClinicalTrials.gov | |
| NCT01371838 | A Study to Evaluate the Efficacy and Safety of Intravenous Ceftaroline Versus Intravenous Ceftriaxone in the Treatment of Adult Hospitalised Patients With Community-Acquired Bacterial Pneumonia in Asia | Phase 3 | 848 | 2014-09-23 | ceftriaxone | Its name | ClinicalTrials.gov |
| NCT04010539 | A Study Evaluating Efficacy and Safety of Gepotidacin Compared With Ceftriaxone Plus Azithromycin in the Treatment of Uncomplicated Urogenital Gonorrhea | Phase 3 | 628 | 2024-05-30 | ceftriaxone | Its name | ClinicalTrials.gov |
| NCT01659866 | Antibiotic Prophylaxis for Transrectal Prostate Biopsy | Phase 4 | 563 | 2019-06-25 | ceftriaxone | Its name | ClinicalTrials.gov |
| NCT00349622 | Clinical Trial Ceftriaxone in Subjects With ALS | Phase 3 | 513 | 2014-04-01 | ceftriaxone | Its name | ClinicalTrials.gov |
| NCT00230971 | Study Comparing Tigecycline Versus Ceftriaxone Sodium Plus Metronidazole in Complicated Intra-abdominal Infection (cIAI) | Phase 4 | 473 | 2010-04-26 | ceftriaxone | Its name | ClinicalTrials.gov |
| NCT02015637 | Comparison of Delafloxacin Versus Ceftriaxone for the Treatment of Uncomplicated Gonorrhea | Phase 3 | 460 | 2018-04-26 | ceftriaxone | Its name | ClinicalTrials.gov |
| NCT02567825 | Efficacy of Tympanostomy Tubes for Children With Recurrent Acute Otitis Media | 250 | 2021-12-10 | ceftriaxone | Its name | ClinicalTrials.gov | |
| NCT01160640 | The Importance of Anti-anaerobic Therapy for Acute Pelvic Inflammatory Disease (PID) | Phase 2 | 233 | 2016-12-21 | ceftriaxone | Its name | ClinicalTrials.gov |
| NCT05470517 | Antibiotic Instillation in Appendicitis | Phase 2 | 190 | 2025-03-13 | ceftriaxone | Its name | ClinicalTrials.gov |
1 to 10 of 140
See all 140 trialsComparisons in its trials95
Comparisons Trial comparisons calculated in the trials whose record names the drug, most participants first. A comparison in one of its trials does not always compare the drug, so read the two groups.
| Comparison | Group 1, with the outcome | Group 2, with the outcome | Participants | Trial | Source |
|---|---|---|---|---|---|
| Antibiotics Therapy Arm vs Appendectomy Arm: Rates of Participants With Appendiceal Cancer | 4 of 776 | 6 of 776 | 1,552 | NCT02800785 | Trial comparisons |
| Antibiotics Therapy Arm vs Appendectomy Arm: Total Number of Patients Who Had Resolution of Appendicitis Symptoms at 30 Days | 462 of 676 | 466 of 663 | 1,339 | NCT02800785 | Trial comparisons |
| Antibiotics Therapy Arm vs Appendectomy Arm: Number of Participants With at Least One Complications From Treatment | 37 of 676 | 21 of 656 | 1,332 | NCT02800785 | Trial comparisons |
| Antibiotics Therapy Arm vs Appendectomy Arm: deaths from any cause | 0 of 676 | 0 of 656 | 1,332 | NCT02800785 | Trial comparisons |
| Antibiotics Therapy Arm vs Appendectomy Arm: serious adverse events | 19 of 676 | 19 of 656 | 1,332 | NCT02800785 | Trial comparisons |
| Antibiotics Therapy Arm vs Appendectomy Arm: Rate of Participants With Perforated Appendicitis | 59 of 185 | 99 of 621 | 806 | NCT02800785 | Trial comparisons |
| Ceftaroline 600mg vs Ceftriaxone 2g: serious adverse events | 30 of 381 | 29 of 383 | 764 | NCT01371838 | Trial comparisons |
| Gepotidacin vs Ceftriaxone Plus Azithromycin: deaths from any cause | 0 of 309 | 0 of 313 | 622 | NCT04010539 | Trial comparisons |
| Gepotidacin vs Ceftriaxone Plus Azithromycin: serious adverse events | 1 of 309 | 0 of 313 | 622 | NCT04010539 | Trial comparisons |
| Ceftriaxone vs Placebo: serious adverse events | 276 of 340 | 125 of 173 | 513 | NCT00349622 | Trial comparisons |
1 to 10 of 95
See all 95 comparisons in its trialsPapers from its trials159
The papers the trials whose record names the drug list on ClinicalTrials.gov as their results (RESULT) or as drawn from them (DERIVED), results first, newest first.
Tests in its trials1
The tests ConductCognition runs that the trials whose record names the drug name in their registered outcomes, as ScienceGraph matched them. ConductCognition's list names the tests it runs, not every test a trial used.
| Test | Trials naming it as an outcome | As a primary outcome |
|---|---|---|
| Line Angle Matching | 1 | 0 |
Source ConductCognition
Data dates
The date of each source this release read.
Sources 7
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ConductCognition's list of its testsOur own data
- ClinicalTrials.govNo license stated
- NLM's MeSHNLM's terms
- Open TargetsCC0 1.0
- PubMedNLM's terms
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ConductCognition's list of its testsOur own data: ConductCognition's list of its tests, https://conductcognition.com
- ClinicalTrials.govnone stated
- NLM's MeSHNLM's
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this drug from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/drugs/v1/CHEMBL161
GET https://conductscience.org/api/drugs/v1/CHEMBL161/diseases?page=2