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Drugs and targets

One record for each drug in Open Targets 26.09 that acts on a target, is paired with a disease or is named by a trial. Each joins the drug to the targets ChEMBL's mechanism records give it, the diseases Open Targets pairs it with, each with its stage and the sources of that stage, and the ClinicalTrials.gov trials whose record names it, with the comparisons, papers and cognitive tests of those trials. Posted results are those in CTTI's AACT copy of 23 Mar 2026.

7 sources

Search Drugs and targets.

A drug's name, brand name or code, or its ChEMBL ID; a target's symbol or Ensembl ID; or a disease's name or ID. Case and punctuation do not matter. Other words find the drugs whose names hold every one or, when none does, the targets and diseases whose names do.

12,618 drugs from Open Targets.

Try searching

Drugs and targets 12,618

Most trials with posted results first1 to 20 of 12,618

Show the results as
DrugChEMBL IDTrialsWith posted resultsTargetsDiseases
CYCLOPHOSPHAMIDE

Cytoxan, Cytoxan (lyophilized), Endoxana, Lyophilized cytoxan, Neosar

CHEMBL1200796

Small molecule

3,5169170423
PACLITAXEL

Abraxane, Apealea, Apexelsin, Naveruclif, Pacitaxel, Paclitaxel component of abi 007, Paclitaxel component of abraxane, Paclitaxel component of nab-, Paclitaxel component of oraxol, Paxene, Pazenir, Taxol, Taxol 100, Zisu

CHEMBL428647

Small molecule

3,69189315266
BEVACIZUMAB

Abevmy, Alymsys, Avastin, Avzivi, Aybintio, Equidacent, Lextemy, Mvasi, Onbevzi, Oyavas, Vegzelma, Zirabev

CHEMBL1201583

Antibody

2,6437621273
CARBOPLATIN

Paraplatin

CHEMBL1351

Small molecule

3,0137520283
DEXAMETHASONE

Aeroseb-dex, Decaderm, Decadron, Decadron-75, Decaspray, Dexa-sine, Dexacortal, Dexacortin, Dexacortisyl, Dexafree, Dexamethasone component of ciprodex, Dexamethasone component of dexacidin, Dexamethasone component of dexasporin, Dexamethasone component of maxitrol, Dexamethasone component of tobradex, Dexamethasone component of tobradex st, Dexamethasone intensol, Dexamonozon, Dexapos, Dexasite, Dexasone, Dexone, Dexone 0.5, Dexone 0.75, Dexone 1.5, Dexone 4, Dexsol, Dextenza, Dexycu kit, Dropodex, Fortecortin, Gppe ear spy, Hemady, Hexadrol, Isopto-dex, Kortico injection, Loverine, Luxazone, Martapan, Maxidex, Maxitrol, Oradexon, Otomize, Ozurdex, Sofradex, Spersadex comp, Tobradex

CHEMBL384467

Small molecule

3,1057341445
PEMBROLIZUMAB

Keytruda, Pembrolizumab component of mk 7684a, Pembrolizumab component of mk-1308a

CHEMBL3137343

Antibody

2,5187291261
RITUXIMAB

Blitzima, Mabthera, Mabthera rituxan, Ritemvia, Rituxan, Rituximab component of rituxan hycela, Rituzena (previously tuxella), Rixathon, Riximyo, Ruxience, Truxima

CHEMBL1201576

Antibody

2,2506881219
CISPLATIN

Platinol, Platinol-aq

CHEMBL11359

Small molecule

3,4416670296
GEMCITABINE

Gemzar

CHEMBL888

Small molecule

2,54454614199
DOCETAXEL

Beizray, Docetaxel accord, Docetaxel teva, Docetaxel zentiva (previously docetaxel winthrop), Docivyx, Taxceus, Taxespira (previously docetaxel hospira uk limited ), Taxotere

CHEMBL3545252

Small molecule

2,25153315171
NIVOLUMAB

Nivolumab bms, Nivolumab component of bms-986213, Nivolumab component of opdualag, Opdivo

CHEMBL2108738

Antibody

1,7264911280
FLUOROURACIL

5.f.u., Accusite, Actikerall, Adrucil, Carac, Efudex, Efudix, Fluoro-uracil roche, Fluoroplex, Fluorouracil component of folfox, Tolak

CHEMBL185

Small molecule

2,3604381190
METFORMINCHEMBL1431

Small molecule

1,91843151247
PREDNISONE

Cortan, Cortancyl, Decortisyl, Delta-dome, Deltasone, Fernisone, Liquid pred, Lodotra, Meticorten, Orasone, Paracort, Prednicen-m, Prednisone intensol, Rayos, Servisone, Sterapred

CHEMBL635

Small molecule

1,4164021370
RIBAVIRIN

Copegus, Cotronak, Rebetol, Ribapak, Ribasphere, Ribavarin, Ribavirin biopartners, Ribavirin mylan (previously ribavirin three rivers), Ribavirin teva, Ribavirin teva pharma b.v., Ribofluranosyl carboxamide, Viramid, Virazid, Virazole

CHEMBL1643

Small molecule

859398145
BUPIVACAINE

Anekain, Bupivacaine component of zynrelef, Exparel, Exparel liposomal, Posimir

CHEMBL1098

Small molecule

1,9063851100
METHOTREXATE

Ebetrex, Emtexate high-pot, Emtexate pf, Jylamvo, Maxtrex, Metoject, Nordimet, Otrexup, Otrexup pfs, Rasuvo, Reditrex, Zlatal

CHEMBL34259

Small molecule

1,3733811258
CAPECITABINE

Capecitabine accord, Capecitabine component of xeliri capecitibine, Capecitabine component of xelox, Capecitabine medac, Capecitabine sun, Capecitabine teva, Ecansya (previously capecitabine krka), Xeloda

CHEMBL1773

Small molecule

2,0803741139
OXALIPLATIN

Eloxatin, Oxaliplatin component of folfox, Oxaliplatin component of xelox

CHEMBL414804

Small molecule

2,3063680157
LENALIDOMIDE

Lenalidomide accord, Lenalidomide mylan, Revlimid

CHEMBL848

Small molecule

1,1173678133

Request

GET /api/drugs/v1

A drug's name, brand name or code, or its ChEMBL ID; a target's symbol or Ensembl ID; or a disease's name or ID. Case and punctuation do not matter. Other words find the drugs whose names hold every one or, when none does, the targets and diseases whose names do.

Only the drugs with a trial that posted results to ClinicalTrials.gov.

No key needed

Code

Show the call in
curl "https://conductscience.org/api/drugs/v1"

Response

The first 2 of this page's 20 results. GET /api/drugs/v1

{
  "data": {
    "total": 12618,
    "results": [
      {
        "id": "CHEMBL1200796",
        "title": "CYCLOPHOSPHAMIDE",
        "name": "CYCLOPHOSPHAMIDE",
        "summary": "Small molecule, CHEMBL1200796. 3,516 trials, 917 with posted results.",
        "record": "/library/drugs/CHEMBL1200796",
        "drug_type": "Small molecule",
        "brands": "Cytoxan, Cytoxan (lyophilized), Endoxana, Lyophilized cytoxan, Neosar",
        "counts": {
          "trials": 3516,
          "trials_with_results": 917,
          "targets": 0,
          "diseases": 423,
          "comparisons": 686,
          "papers": 2248,
          "tests": 19
        }
      },
      {
        "id": "CHEMBL428647",
        "title": "PACLITAXEL",
        "name": "PACLITAXEL",
        "summary": "Small molecule, CHEMBL428647. 3,691 trials, 893 with posted results.",
        "record": "/library/drugs/CHEMBL428647",
        "drug_type": "Small molecule",
        "brands": "Abraxane, Apealea, Apexelsin, Naveruclif, Pacitaxel, Paclitaxel component of abi 007, Paclitaxel component of abraxane, Paclitaxel component of nab-, Paclitaxel component of oraxol, Paxene, Pazenir, Taxol, Taxol 100, Zisu",
        "counts": {
          "trials": 3691,
          "trials_with_results": 893,
          "targets": 15,
          "diseases": 266,
          "comparisons": 637,
          "papers": 1975,
          "tests": 1
        }
      }
    ],
    "columns": [
      {
        "key": "name",
        "label": "Drug",
        "under": "brands"
      },
      {
        "key": "id",
        "label": "ChEMBL ID",
        "under": "drug_type"
      },
      {
        "key": "counts.trials",
        "label": "Trials"
      },
      {
        "key": "counts.trials_with_results",
        "label": "With posted results"
      },
      {
        "key": "counts.targets",
        "label": "Targets"
      },
      {
        "key": "counts.diseases",
        "label": "Diseases"
      }
    ],
    "order": "Most trials with posted results first",
    "kinds": {
      "all": 12618,
      "with-results": 5231
    }
  },
  "release": "pipelines-2026-09-18-0.3.1",
  "terms": [
    {
      "source": "ClinicalTrials.gov's posted results, through CTTI's AACT",
      "license": "ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299",
      "notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.",
      "short": "Freely available. Acknowledgement requested"
    },
    {
      "source": "ChEMBL, through Open Targets",
      "license": "CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence",
      "notice": null,
      "short": "CC BY-SA 3.0"
    },
    {
      "source": "ConductCognition's list of its tests",
      "license": "Our own data: ConductCognition's list of its tests, https://conductcognition.com",
      "notice": null,
      "short": "Our own data"
    },
    {
      "source": "ClinicalTrials.gov",
      "license": "none stated",
      "notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.",
      "short": "No license stated"
    },
    {
      "source": "NLM's MeSH",
      "license": "NLM's",
      "notice": null,
      "short": "NLM's terms"
    },
    {
      "source": "Open Targets",
      "license": "CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence",
      "notice": null,
      "short": "CC0 1.0"
    },
    {
      "source": "PubMed",
      "license": "NLM's terms",
      "notice": null,
      "short": "NLM's terms"
    }
  ],
  "next": "/api/drugs/v1?page=2",
  "request_id": "AKg8V3lHmi6EYqZg"
}

What it holds

Holds
12,618 drugs
From Open Targets. Counted 14 Nov 2026.
Release
18 Sept 2026
pipelines-2026-09-18-0.3.1
Checked
Trial links by the drug's name passed automated checks: the trials' own result groups confirm 93% of those they can check, and NLM's indexing of their papers 73%
Access
Open
No account. 60 calls a minute from one address.

The 6 lists in a drug's record, and how many drugs have each.

  • Targets

    The targets ChEMBL's mechanism records give for the drug, through Open Targets. A mechanism record says what the drug acts on, not how strongly.

    5,05240.0% of drugs

  • Diseases

    The diseases Open Targets' clinical reports study the drug for, the most trial reports first. The stage is Open Targets', the highest any of its sources reports for the pair, and each row names the sources that report it.

    11,37890.2% of drugs

  • Trials

    Trials whose record names the drug by a name ChEMBL states, posted results first, then the largest. Open Targets read each trial's text to find its drugs.

    9,27573.5% of drugs

  • Comparisons in its trials

    Comparisons Trial comparisons calculated in the trials whose record names the drug, most participants first. A comparison in one of its trials does not always compare the drug, so read the two groups.

    3,47127.5% of drugs

  • Papers from its trials

    The papers the trials whose record names the drug list on ClinicalTrials.gov as their results (RESULT) or as drawn from them (DERIVED), results first, newest first.

    5,96647.3% of drugs

  • Tests in its trials

    The tests ConductCognition runs that the trials whose record names the drug name in their registered outcomes, as ScienceGraph matched them. ConductCognition's list names the tests it runs, not every test a trial used.

    8877.0% of drugs

Sources 7

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ConductCognition's list of its testsOur own data
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ConductCognition's list of its testsOur own data: ConductCognition's list of its tests, https://conductcognition.com
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

Genes

NCBI Gene

One gene with its proteins, patents, drugs, trials, grants and papers.

Trials

ClinicalTrials.gov

Search clinical trials by condition, drug, outcome or NCT number, with the results each one posted.

Trial comparisons

ClinicalTrials.gov

Comparisons of the groups of clinical trials, such as a risk ratio or a number needed to treat, calculated from the counts each trial posted.

Sequences

Patent publications

Paste a sequence and see the patents that disclose it.

Opens sequences.conductscience.org

For software

Read Drugs and targets from software.

Every answer on this page is also JSON, under /api/drugs/v1. No key.

GET https://conductscience.org/api/drugs/v1?q=Repatha

Ask an assistant

  • Which trials of evolocumab posted results, and how many people took part in each?
  • Which drugs act on PCSK9, and by what mechanism?
  • Which drugs have been studied for Alzheimer's disease, and what stage does Open Targets give each?
  • Which cognitive tests do the trials of methylphenidate name as outcomes?