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Drug · CHEMBL4650488

ETESEVIMAB

7 sourcespipelines-2026-09-18-0.3.1

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ConductScience Library. ETESEVIMAB. Drugs and targets, record CHEMBL4650488. Release pipelines-2026-09-18-0.3.1, 18 Sept 2026. https://conductscience.org/library/drugs/CHEMBL4650488

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Drug

Names and IDs as ChEMBL gives them, through Open Targets.

Name
ETESEVIMAB
ChEMBL
ChEMBL ID
CHEMBL4650488
ChEMBL
Type
Antibody
ChEMBL
Other names
Anti-sars-cov-2 antibody js016, CB-6, CB6, JS-016, JS016, LY COV016, LY-3832479, LY-COV016, LY3832479, Ly3832479, NP-005, NP005
ChEMBL
Open Targets' highest stage
Approval, as Open Targets' drug record gives it
Open Targets

Targets0

The targets ChEMBL's mechanism records give for the drug, through Open Targets. A mechanism record says what the drug acts on, not how strongly.

None in this release.

Diseases1

The diseases Open Targets' clinical reports study the drug for, the most trial reports first. The stage is Open Targets', the highest any of its sources reports for the pair, and each row names the sources that report it.

DiseaseOpen Targets' stageStage reported byReportsOf them trialsIts drugs
COVID-19Phase 3ClinicalTrials.gov1413https://conductscience.org/library/drugs?q=MONDO_0100096

Trials19

Trials whose record names the drug by a name ChEMBL states, posted results first, then the largest. Open Targets read each trial's text to find its drugs.

TrialTitlePhaseParticipantsResults first postedNamed asLinked bySource
NCT04790786UPMC OPTIMISE-C19 Trial, a COVID-19 StudyPhase 44,5712023-06-15etesevimabIts nameClinicalTrials.gov
NCT04427501A Study of LY3819253 (LY-CoV555) and LY3832479 (LY-CoV016) in Participants With Mild to Moderate COVID-19 IllnessPhase 2/33,3072022-03-07etesevimabIts nameClinicalTrials.gov
NCT04634409A Study of Immune System Proteins in Participants With Mild to Moderate COVID-19 IllnessPhase 21,7552022-07-01etesevimabIts nameClinicalTrials.gov
NCT04602000A Phase 2/3 Study to Evaluate the Efficacy and Safety of CT-P59 in Patients With Mild to Moderate SARS-CoV-2 InfectionPhase 2/31,6422022-07-20etesevimabIts nameClinicalTrials.gov
NCT04497987A Study of LY3819253 (LY-CoV555) and LY3832479 (LY-CoV016) in Preventing SARS-CoV-2 Infection and COVID-19 in Nursing Home Residents and StaffPhase 31,1802022-02-04etesevimabIts nameClinicalTrials.gov
NCT04913675Intramuscular and Intravenous VIR-7831 (Sotrovimab) for Mild/Moderate COVID-19.Phase 31,0652023-05-26etesevimabIts nameClinicalTrials.gov
NCT04441931A Study of LY3832479 (LY-CoV016) in Healthy ParticipantsPhase 1262021-12-06LY3832479Its nameClinicalTrials.gov
NCT04611789A Study of LY3832479 (LY-CoV016) in Healthy Participants 1Phase 1182021-12-06LY3832479Its nameClinicalTrials.gov
NCT05205759Non-inferiority Trial on Monoclonal Antibodies in COVID-19Phase 3319etesevimabIts nameClinicalTrials.gov
NCT04931238Efficacy and Safety of JS016 in Patients With SARS-CoV-2 Infection (COVID-19)Phase 2200JS016Its nameClinicalTrials.gov

1 to 10 of 19

See all 19 trials

Comparisons in its trials4

Comparisons Trial comparisons calculated in the trials whose record names the drug, most participants first. A comparison in one of its trials does not always compare the drug, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
CT-P59 40 mg/kg Group (Part 2) vs Placebo Group (Part 2): Proportion of Patients With Clinical Symptom Requiring Hospitalization, Oxygen Therapy, or Experiencing Mortality Due to SARS-CoV-2 Infection up to Day 28 in All Randomized Patients (Part 2)
16 of 65653 of 6591,315NCT04602000Trial comparisons
4200mg Bamlanivimab vs Placebo: deaths from any cause13 of 58821 of 5871,175NCT04497987Trial comparisons
4200mg Bamlanivimab vs Placebo: serious adverse events39 of 58830 of 5871,175NCT04497987Trial comparisons
CT-P59 40 mg/kg Group (Part 2) vs Placebo Group (Part 2): Proportion of Patients With Clinical Symptom Requiring Hospitalization, Oxygen Therapy, or Experiencing Mortality Due to SARS-CoV-2 Infection up to Day 28 in High-risk Patients (Part 2)
14 of 44648 of 434880NCT04602000Trial comparisons

Papers from its trials24

The papers the trials whose record names the drug list on ClinicalTrials.gov as their results (RESULT) or as drawn from them (DERIVED), results first, newest first.

PMIDListed asTrials listing itSource
33215063RESULT1PubMed
39230829DERIVED1PubMed
38291279DERIVED1PubMed
37577112DERIVED1PubMed
37520411DERIVED1PubMed
37329415DERIVED1PubMed
36413383DERIVED1PubMed
36043180DERIVED1PubMed
35834252DERIVED1PubMed
35713300DERIVED6PubMed

Tests in its trials0

The tests ConductCognition runs that the trials whose record names the drug name in their registered outcomes, as ScienceGraph matched them. ConductCognition's list names the tests it runs, not every test a trial used.

None in this release.

Data dates

The date of each source this release read.

Open Targets
2026-09-18
Open Targets
ClinicalTrials.gov
2026-11-05
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
Papers the trials list, from Trials
2026-11-12
Trials
Comparisons, from Trial comparisons
2026-03-23
Trial comparisons
Tests named in the trials, as ScienceGraph matched them
2026-11-12
ConductCognition

Sources 7

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ConductCognition's list of its testsOur own data
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ConductCognition's list of its testsOur own data: ConductCognition's list of its tests, https://conductcognition.com
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this drug from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/drugs/v1/CHEMBL4650488

GET https://conductscience.org/api/drugs/v1/CHEMBL4650488/papers?page=2