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Drug · CHEMBL47

ALPHA-TOCOPHEROL

7 sourcespipelines-2026-09-18-0.3.1

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ConductScience Library. ALPHA-TOCOPHEROL. Drugs and targets, record CHEMBL47. Release pipelines-2026-09-18-0.3.1, 18 Sept 2026. https://conductscience.org/library/drugs/CHEMBL47

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Drug

Names and IDs as ChEMBL gives them, through Open Targets.

Name
ALPHA-TOCOPHEROL
ChEMBL
ChEMBL ID
CHEMBL47
ChEMBL
Type
Small molecule
ChEMBL
Other names
E307
ChEMBL
DrugBank
DB00163
DrugBank
InChIKey
GVJHHUAWPYXKBD-IEOSBIPESA-N
ChEMBL
Open Targets' highest stage
Approval, as Open Targets' drug record gives it
Open Targets

Targets0

The targets ChEMBL's mechanism records give for the drug, through Open Targets. A mechanism record says what the drug acts on, not how strongly.

None in this release.

Diseases11

The diseases Open Targets' clinical reports study the drug for, the most trial reports first. The stage is Open Targets', the highest any of its sources reports for the pair, and each row names the sources that report it.

DiseaseOpen Targets' stageStage reported byReportsOf them trialsIts drugs
Alzheimer diseasePhase 3ClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0004975
COVID-19Early phase 1ClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0100096
Tetralogy of FallotEarly phase 1ClinicalTrials.gov11https://conductscience.org/library/drugs?q=HP_0001636
beta-thalassemia majorUnknownClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0016486
carotid atherosclerosisPhase 2ClinicalTrials.gov11https://conductscience.org/library/drugs?q=EFO_0009783
coronary artery disorderPhase 2ClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0005010
hemolysisUnknownClinicalTrials.gov11https://conductscience.org/library/drugs?q=EFO_0009473
injuryPhase 1ClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0021178
oxidative stressUnknownClinicalTrials.gov11https://conductscience.org/library/drugs?q=EFO_1001905
preterm premature rupture of the membranesPhase 3ClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0012511

Trials14

Trials whose record names the drug by a name ChEMBL states, posted results first, then the largest. Open Targets read each trial's text to find its drugs.

TrialTitlePhaseParticipantsResults first postedNamed asLinked bySource
NCT00235716A Randomized, Clinical Trial of Vitamin E and Memantine in Alzheimer's DiseasePhase 36132014-01-29alpha-tocopherolIts nameClinicalTrials.gov
NCT00339768A Randomized Multi-Intervention Trial to Inhibit Precancerous Gastric Lesions in Lingu, Shandong ProvincePhase 33,411alpha-tocopherolIts nameClinicalTrials.gov
NCT01594346Multicenter Vitamin E Trial in Aging Persons With Down SyndromePhase 3349alpha tocopherolIts nameClinicalTrials.gov
NCT01266928Does Vitamins C and E Supplementation of After Preterm Rupture of Membranes Prolong the Duration of Latency? A Prospective Randomized Controlled StudyPhase 3244alpha-tocopherolIts nameClinicalTrials.gov
NCT00010699Effect of High Dose Vitamin E on Carotid AtherosclerosisPhase 2120alpha-tocopherolIts nameClinicalTrials.gov
NCT0000258613-Cis Retinoic Acid With or Without Vitamin E for Prevention of Lung CancerPhase 296alpha tocopherolIts nameClinicalTrials.gov
NCT03358524Effects of Vitamin E Supplementation on Free Radicals and Fat Level of Obese Adolescence in Jakarta, IndonesiaPhase 469alpha-tocopherolIts nameClinicalTrials.gov
NCT07194304Effect of Parenteral Alpha-Tocopherol in the Definitive Surgery of Tetralogy of FallotEarly phase 160alpha-tocopherolIts nameClinicalTrials.gov
NCT07412574Vitamin E Supplementation As Adjunctive Therapy To Lower Inflammation In COVID-19 PatientsEarly phase 156alpha-tocopherolIts nameClinicalTrials.gov
NCT03948737The Effect of Alpha-tocopherol in Hemolysis and Oxidative Stress Marker on the Red Cell Membrane Beta-thalassemia Major40alpha-tocopherolIts nameClinicalTrials.gov

1 to 10 of 14

See all 14 trials

Comparisons in its trials0

Comparisons Trial comparisons calculated in the trials whose record names the drug, most participants first. A comparison in one of its trials does not always compare the drug, so read the two groups.

None in this release.

Papers from its trials13

The papers the trials whose record names the drug list on ClinicalTrials.gov as their results (RESULT) or as drawn from them (DERIVED), results first, newest first.

PMIDListed asTrials listing itSource
29333256RESULT1PubMed
26285072RESULT1PubMed
26175690RESULT1PubMed
25389409RESULT1PubMed
24381967RESULT1PubMed
23995229RESULT1PubMed
23105782RESULT1PubMed
19401528RESULT1PubMed
16506966RESULT1PubMed
15981230RESULT1PubMed

Tests in its trials0

The tests ConductCognition runs that the trials whose record names the drug name in their registered outcomes, as ScienceGraph matched them. ConductCognition's list names the tests it runs, not every test a trial used.

None in this release.

Data dates

The date of each source this release read.

Open Targets
2026-09-18
Open Targets
ClinicalTrials.gov
2026-11-05
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
Papers the trials list, from Trials
2026-11-12
Trials
Comparisons, from Trial comparisons
2026-03-23
Trial comparisons
Tests named in the trials, as ScienceGraph matched them
2026-11-12
ConductCognition

Sources 7

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ConductCognition's list of its testsOur own data
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ConductCognition's list of its testsOur own data: ConductCognition's list of its tests, https://conductcognition.com
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this drug from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/drugs/v1/CHEMBL47

GET https://conductscience.org/api/drugs/v1/CHEMBL47/targets