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Drug · CHEMBL55

PENTAMIDINE

7 sourcespipelines-2026-09-18-0.3.1

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ConductScience Library. PENTAMIDINE. Drugs and targets, record CHEMBL55. Release pipelines-2026-09-18-0.3.1, 18 Sept 2026. https://conductscience.org/library/drugs/CHEMBL55

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Drug

Names and IDs as ChEMBL gives them, through Open Targets.

Name
PENTAMIDINE
ChEMBL
ChEMBL ID
CHEMBL55
ChEMBL
Type
Small molecule
ChEMBL
Brand names
Pentacarinat
ChEMBL
Other names
GNF-Pf-3680, MB 800 FREE BASE, MB-800, MB-800 (AS ISETHIONATE), MB-800 FREE BASE, Mp-601205, NSC-9921, Pentam 300, Pentamidina, RP 2512 FREE BASE, RP-2512, RP-2512 FREE BASE
ChEMBL
Other form
PENTAMIDINE ISETHIONATE, CHEMBL361506
Drugs and targets
DrugBank
DB00738
DrugBank
InChIKey
XDRYMKDFEDOLFX-UHFFFAOYSA-N
ChEMBL
Open Targets' highest stage
Approval, for 1 of its 12 diseases, from TTD, at withdrawal
Open Targets

Targets0

The targets ChEMBL's mechanism records give for the drug, through Open Targets. A mechanism record says what the drug acts on, not how strongly.

None in this release.

Diseases12

The diseases Open Targets' clinical reports study the drug for, the most trial reports first. The stage is Open Targets', the highest any of its sources reports for the pair, and each row names the sources that report it.

DiseaseOpen Targets' stageStage reported byReportsOf them trialsIts drugs
pneumocystosisPhase 3ClinicalTrials.gov66https://conductscience.org/library/drugs?q=MONDO_0019121
AIDSPhase 3ClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0012268
Lymphoma, AIDS-RelatedPhase 2ClinicalTrials.gov11https://conductscience.org/library/drugs?q=EFO_1001365
alcoholic fatty liver diseasePhase 1ClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0021104
aplastic anemiaPhase 2ClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0015909
classic Hodgkin lymphomaPhase 1ClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0009348
cutaneous leishmaniasisPhase 2ClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0005446
exocrine pancreatic carcinomaPhase 1/2ClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0005192
hepatocellular carcinomaPhase 1ClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0007256
human African trypanosomiasisPhase 2ClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0005459

Trials26

Trials whose record names the drug by a name ChEMBL states, posted results first, then the largest. Open Targets read each trial's text to find its drugs.

TrialTitlePhaseParticipantsResults first postedNamed asLinked bySource
NCT01360762Prophylaxis of Visceral Leishmaniasis Relapses in HIV Co-infected Patients With Pentamidine: a Cohort StudyPhase 3742019-02-15pentamidineIts nameClinicalTrials.gov
NCT00944749Horse ATG/CsA in Aplastic Anemia Patients Unresponsive to or With a Suboptimal Response to Rabbit ATG/CsA TreatmentPhase 2232017-02-23pentamidineIts nameClinicalTrials.gov
NCT007298070794GCC: Pentamidine in Treating Patients With Relapsed or Refractory MelanomaPhase 262016-10-21pentamidineIts nameClinicalTrials.gov
NCT00002340A Comparison of Atovaquone and Pentamidine in the Prevention of Pneumocystis Carinii Pneumonia in HIV-Infected Patients Who Cannot Take TMP/SMXPhase 3615pentamidineIts nameClinicalTrials.gov
NCT00000991A Study of Three Drugs Plus Zidovudine in the Prevention of Infections in HIV-Infected PatientsPhase 3600pentamidineIts nameClinicalTrials.gov
NCT07357103Positioning Second-line Therapies for Pneumocystis Jirovecii Pneumonia (PCP Alternatives)Phase 4416pentamidineIts nameClinicalTrials.gov
NCT00001028A Study of Pentamidine Plus Dapsone in the Prevention of Pneumocystis Carinii Pneumonia (PCP) in HIV-Infected Patients Who Cannot Take Trimethoprim or SulfonamidesPhase 3400pentamidineIts nameClinicalTrials.gov
NCT00000727
A Controlled Comparative Trial of Sulfamethoxazole-Trimethoprim Versus Aerosolized Pentamidine for Secondary Prophylaxis of Pneumocystis Carinii Pneumonia in AIDS Patients Receiving Azidothymidine (AZT)
Phase 3322pentamidineIts nameClinicalTrials.gov
NCT00000715A Controlled Trial Comparing the Efficacy of Aerosolized Pentamidine and Parenteral/Oral Sulfamethoxazole-Trimethoprim in the Treatment of Pneumocystis Carinii Pneumonia in AIDSPhase 3240pentamidineIts nameClinicalTrials.gov
NCT00000730Comparison of Three Treatments for Pneumocystis Pneumonia in AIDS PatientsPhase 3240pentamidineIts nameClinicalTrials.gov

1 to 10 of 26

See all 26 trials

Comparisons in its trials0

Comparisons Trial comparisons calculated in the trials whose record names the drug, most participants first. A comparison in one of its trials does not always compare the drug, so read the two groups.

None in this release.

Papers from its trials10

The papers the trials whose record names the drug list on ClinicalTrials.gov as their results (RESULT) or as drawn from them (DERIVED), results first, newest first.

PMIDListed asTrials listing itSource
38235979RESULT1PubMed
36395328RESULT1PubMed
34988242RESULT1PubMed
32479781RESULT1PubMed
27927991RESULT1PubMed
34724566DERIVED1PubMed
29269796DERIVED1PubMed
29020217DERIVED1PubMed
26881924DERIVED1PubMed
24415649DERIVED1PubMed

Tests in its trials0

The tests ConductCognition runs that the trials whose record names the drug name in their registered outcomes, as ScienceGraph matched them. ConductCognition's list names the tests it runs, not every test a trial used.

None in this release.

Data dates

The date of each source this release read.

Open Targets
2026-09-18
Open Targets
ClinicalTrials.gov
2026-11-05
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
Papers the trials list, from Trials
2026-11-12
Trials
Comparisons, from Trial comparisons
2026-03-23
Trial comparisons
Tests named in the trials, as ScienceGraph matched them
2026-11-12
ConductCognition

Sources 7

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ConductCognition's list of its testsOur own data
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ConductCognition's list of its testsOur own data: ConductCognition's list of its tests, https://conductcognition.com
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this drug from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/drugs/v1/CHEMBL55

GET https://conductscience.org/api/drugs/v1/CHEMBL55/trials?page=2