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Drug · CHEMBL602

CYSTEAMINE

7 sourcespipelines-2026-09-18-0.3.1

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ConductScience Library. CYSTEAMINE. Drugs and targets, record CHEMBL602. Release pipelines-2026-09-18-0.3.1, 18 Sept 2026. https://conductscience.org/library/drugs/CHEMBL602

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Drug

Names and IDs as ChEMBL gives them, through Open Targets.

Name
CYSTEAMINE
ChEMBL
ChEMBL ID
CHEMBL602
ChEMBL
Type
Small molecule
ChEMBL
Brand names
Cystagon
ChEMBL
Other names
L-1573, MEA, Mercaptamina, Mercaptamine, NSC-647528
ChEMBL
Other form
CYSTEAMINE BITARTRATE, CHEMBL1200577
Drugs and targets
Other form
CYSTEAMINE HYDROCHLORIDE, CHEMBL1256137
Drugs and targets
DrugBank
DB00847
DrugBank
InChIKey
UFULAYFCSOUIOV-UHFFFAOYSA-N
ChEMBL
Open Targets' highest stage
Approval, for 3 of its 16 diseases, from ATC, EMA Human Drugs and TTD
Open Targets

Targets0

The targets ChEMBL's mechanism records give for the drug, through Open Targets. A mechanism record says what the drug acts on, not how strongly.

None in this release.

Diseases16

The diseases Open Targets' clinical reports study the drug for, the most trial reports first. The stage is Open Targets', the highest any of its sources reports for the pair, and each row names the sources that report it.

DiseaseOpen Targets' stageStage reported byReportsOf them trialsIts drugs
cystinosisApprovalEMA Human Drugs74https://conductscience.org/library/drugs?q=MONDO_0016239
COVID-19Phase 3ClinicalTrials.gov22https://conductscience.org/library/drugs?q=MONDO_0100096
frecklesPhase 3ClinicalTrials.gov22https://conductscience.org/library/drugs?q=EFO_0003963
Growth delayUnknownClinicalTrials.gov11https://conductscience.org/library/drugs?q=HP_0001510
HIV infectious diseasePhase 2ClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0005109
Huntington diseasePhase 2/3ClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0007739
Leigh syndromePhase 2ClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0009723
PhotophobiaUnknownClinicalTrials.gov11https://conductscience.org/library/drugs?q=HP_0000613
asthmaPhase 1ClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0004979
cystic fibrosisPhase 1/2ClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0009061

Trials16

Trials whose record names the drug by a name ChEMBL states, posted results first, then the largest. Open Targets read each trial's text to find its drugs. 2 more that Open Targets linked to it are not shown, since the release's checks do not confirm them.

TrialTitlePhaseParticipantsResults first postedNamed asLinked bySource
NCT00001213Cysteamine Eye Drops to Treat Corneal Crystals in CystinosisPhase 23282014-07-22cysteamineIts nameClinicalTrials.gov
NCT03000348A Study of the Dosing, Efficacy, and Safety of Oral Cysteamine in Adult Patients With Cystic Fibrosis ExacerbationsPhase 2912021-04-14cysteamineIts nameClinicalTrials.gov
NCT00799578A Preliminary Study to Evaluate Cysteamine Therapy in Human Subjects With Non-Alcoholic Steatohepatitis (NASH)Phase 1/2132014-01-31cysteamineIts nameClinicalTrials.gov
NCT02735707Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired PneumoniaPhase 320,000cysteamineIts nameClinicalTrials.gov
NCT00002110A Phase II/III Study of Cysteamine (Mercaptoethylamine) and Zidovudine for the Treatment of HIV DiseasePhase 2300cysteamineIts nameClinicalTrials.gov
NCT06278948Efficacy and Tolerability of Test Product Versus Cysteamine 5% in Treatment of Facial Epidermal Melasma140cysteamineIts nameClinicalTrials.gov
NCT02101957Multicentric Trial of the Treatment of Huntington's Disease by Cysteamine (RP103)Phase 2/396cysteamineIts nameClinicalTrials.gov
NCT03883984Cysteamine for AsthmaPhase 160cysteamineIts nameClinicalTrials.gov
NCT00001736New Cysteamine Eye Drops Formulation to Treat Corneal Crystals in CystinosisPhase 151cysteamineIts nameClinicalTrials.gov
NCT07477288Effectiveness of a Bilayering Serum and Cream Containing GABA, DMAE, Cysteamine, and Bakuchiol for Skin Whitening and Anti-AgingPhase 244cysteamineIts nameClinicalTrials.gov

1 to 10 of 16

See all 16 trials

Comparisons in its trials0

Comparisons Trial comparisons calculated in the trials whose record names the drug, most participants first. A comparison in one of its trials does not always compare the drug, so read the two groups.

None in this release.

Papers from its trials31

The papers the trials whose record names the drug list on ClinicalTrials.gov as their results (RESULT) or as drawn from them (DERIVED), results first, newest first.

PMIDListed asTrials listing itSource
40360262RESULT1PubMed
40261382RESULT1PubMed
37888913RESULT1PubMed
37877585RESULT1PubMed
37256341RESULT1PubMed
37039790RESULT1PubMed
36525245RESULT1PubMed
35315874RESULT1PubMed
34606578RESULT1PubMed
34591360RESULT1PubMed

Tests in its trials0

The tests ConductCognition runs that the trials whose record names the drug name in their registered outcomes, as ScienceGraph matched them. ConductCognition's list names the tests it runs, not every test a trial used.

None in this release.

Data dates

The date of each source this release read.

Open Targets
2026-09-18
Open Targets
ClinicalTrials.gov
2026-11-05
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
Papers the trials list, from Trials
2026-11-12
Trials
Comparisons, from Trial comparisons
2026-03-23
Trial comparisons
Tests named in the trials, as ScienceGraph matched them
2026-11-12
ConductCognition

Sources 7

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ConductCognition's list of its testsOur own data
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ConductCognition's list of its testsOur own data: ConductCognition's list of its tests, https://conductcognition.com
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this drug from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/drugs/v1/CHEMBL602

GET https://conductscience.org/api/drugs/v1/CHEMBL602/papers?page=2