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Drug · CHEMBL822

TERBINAFINE

7 sourcespipelines-2026-09-18-0.3.1

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ConductScience Library. TERBINAFINE. Drugs and targets, record CHEMBL822. Release pipelines-2026-09-18-0.3.1, 18 Sept 2026. https://conductscience.org/library/drugs/CHEMBL822

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Drug

Names and IDs as ChEMBL gives them, through Open Targets.

Name
TERBINAFINE
ChEMBL
ChEMBL ID
CHEMBL822
ChEMBL
Type
Small molecule
ChEMBL
Brand names
Lamasil, Lamisil, Lamisil at, Terbinafine component of osurnia
ChEMBL
Other names
SF 86-327, SF-86-327, TDT-067, Terbinafina
ChEMBL
Other form
TERBINAFINE HYDROCHLORIDE, CHEMBL1200832
Drugs and targets
DrugBank
DB00857
DrugBank
InChIKey
DOMXUEMWDBAQBQ-WEVVVXLNSA-N
ChEMBL
Open Targets' highest stage
Approval, for 1 of its 12 diseases, from DailyMed
Open Targets

Targets0

The targets ChEMBL's mechanism records give for the drug, through Open Targets. A mechanism record says what the drug acts on, not how strongly.

None in this release.

Diseases12

The diseases Open Targets' clinical reports study the drug for, the most trial reports first. The stage is Open Targets', the highest any of its sources reports for the pair, and each row names the sources that report it.

DiseaseOpen Targets' stageStage reported byReportsOf them trialsIts drugs
tinea unguiumPhase 3ClinicalTrials.gov and TTD1513https://conductscience.org/library/drugs?q=MONDO_0001628
tinea pedisPhase 3ClinicalTrials.gov22https://conductscience.org/library/drugs?q=MONDO_0005984
tinea infectionApprovalDailyMed51https://conductscience.org/library/drugs?q=MONDO_0005982
Crohn diseasePhase 2ClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0005011
ankylosing spondylitisEarly phase 1ClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0005306
chronic hepatitis B virus infectionPhase 1/2ClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0005366
dermatophytosisPhase 2/3ClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0004678
hepatitis B virus infectionPhase 1/2ClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0005344
paronychiaPhase 2ClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0005898
prostate cancerPhase 2ClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0008315

Trials35

Trials whose record names the drug by a name ChEMBL states, posted results first, then the largest. Open Targets read each trial's text to find its drugs. 3 more that Open Targets linked to it are not shown, since the release's checks do not confirm them.

TrialTitlePhaseParticipantsResults first postedNamed asLinked bySource
NCT00443820Efficacy Safety, and Tolerability of Topical Terbinafine in Patients With Mild to Moderate Toenail Fungus of the Big ToenailPhase 35262011-04-19terbinafineIts nameClinicalTrials.gov
NCT00443898Efficacy, Safety, and Tolerability of Topical Terbinafine in Patients With Mild to Moderate Toenail Fungus of the Big ToenailPhase 35182011-04-20terbinafineIts nameClinicalTrials.gov
NCT01433107Efficacy and Safety of Terbinafine Film Forming Solution in Patients With Tinea PedisPhase 32902013-12-27terbinafineIts nameClinicalTrials.gov
NCT00491764A Study to Evaluate Efficacy and Safety of Four Posaconazole Regimens With Placebo and Terbinafine in the Treatment of Toenail Onychomycosis (Study P05082AM2)(COMPLETED)Phase 22182010-01-28terbinafineIts nameClinicalTrials.gov
NCT01851590Resin vs. Amorolfine vs. Terbinafine Treatment in OnychomycosisPhase 41292015-11-30terbinafineIts nameClinicalTrials.gov
NCT00833586Terbinafine HCl 250 mg Tablet Under Fasting ConditionsPhase 1282009-08-18terbinafineIts nameClinicalTrials.gov
NCT01145807TDT 067 Onychomycosis StudyPhase 3738tdt 067Its nameClinicalTrials.gov
NCT05279846A Vehicle-controlled Study of Topical MOB015B in the Treatment of Distal Subungual Onychomycosis (DSO)Phase 3350terbinafineIts nameClinicalTrials.gov
NCT06369727Study to Evaluate the Sensitizing Potential of MOB015B in Healthy Subjects Using a Repeat Insult Patch Test DesignPhase 1250terbinafineIts nameClinicalTrials.gov
NCT07382427A Phase 2 Study to Assess the Effectiveness of Topical Terbinafine in Participants With Mild to Moderate Onychomycosis of the ToenailsPhase 2200terbinafineIts nameClinicalTrials.gov

1 to 10 of 35

See all 35 trials

Comparisons in its trials3

Comparisons Trial comparisons calculated in the trials whose record names the drug, most participants first. A comparison in one of its trials does not always compare the drug, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
Terbinafine vs Placebo: Number of Subjects With Adverse Event9 of 14611 of 144290NCT01433107Trial comparisons
Terbinafine vs Placebo: serious adverse events0 of 1460 of 144290NCT01433107Trial comparisons
Terbinafine vs Placebo: Effective Treatment Outcome (Direct Microscopy and Culture Negative and Total Signs and Symptom Score Less or Equal to 2)73 of 11510 of 122237NCT01433107Trial comparisons

Papers from its trials8

The papers the trials whose record names the drug list on ClinicalTrials.gov as their results (RESULT) or as drawn from them (DERIVED), results first, newest first.

PMIDListed asTrials listing itSource
35330222RESULT1PubMed
27297276RESULT1PubMed
24352873RESULT1PubMed
24079585RESULT1PubMed
22565425RESULT1PubMed
19968146RESULT1PubMed
14964746RESULT1PubMed
21967490DERIVED1PubMed

Tests in its trials0

The tests ConductCognition runs that the trials whose record names the drug name in their registered outcomes, as ScienceGraph matched them. ConductCognition's list names the tests it runs, not every test a trial used.

None in this release.

Data dates

The date of each source this release read.

Open Targets
2026-09-18
Open Targets
ClinicalTrials.gov
2026-11-05
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
Papers the trials list, from Trials
2026-11-12
Trials
Comparisons, from Trial comparisons
2026-03-23
Trial comparisons
Tests named in the trials, as ScienceGraph matched them
2026-11-12
ConductCognition

Sources 7

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ConductCognition's list of its testsOur own data
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ConductCognition's list of its testsOur own data: ConductCognition's list of its tests, https://conductcognition.com
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this drug from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/drugs/v1/CHEMBL822

GET https://conductscience.org/api/drugs/v1/CHEMBL822/trials?page=2