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Drug · CHEMBL9

NORFLOXACIN

7 sourcespipelines-2026-09-18-0.3.1

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ConductScience Library. NORFLOXACIN. Drugs and targets, record CHEMBL9. Release pipelines-2026-09-18-0.3.1, 18 Sept 2026. https://conductscience.org/library/drugs/CHEMBL9

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Drug

Names and IDs as ChEMBL gives them, through Open Targets.

Name
NORFLOXACIN
ChEMBL
ChEMBL ID
CHEMBL9
ChEMBL
Type
Small molecule
ChEMBL
Brand names
Baccidal, Chibroxin, Noroxin, Quinabic, Utinor
ChEMBL
Other names
MK-366, NSC-757250, Norfloxacine, Norfloxacino
ChEMBL
DrugBank
DB01059
DrugBank
InChIKey
OGJPXUAPXNRGGI-UHFFFAOYSA-N
ChEMBL
Open Targets' highest stage
Approval, for 2 of its 7 diseases, from ATC and TTD
Open Targets

Targets0

The targets ChEMBL's mechanism records give for the drug, through Open Targets. A mechanism record says what the drug acts on, not how strongly.

None in this release.

Diseases7

The diseases Open Targets' clinical reports study the drug for, the most trial reports first. The stage is Open Targets', the highest any of its sources reports for the pair, and each row names the sources that report it.

DiseaseOpen Targets' stageStage reported byReportsOf them trialsIts drugs
Hermansky-Pudlak syndromePhase 2ClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0019312
acute cystitisPhase 3ClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0001650
cirrhosis of liverPhase 3ClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0005155
esophageal varicesPhase 3ClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0001221
portal hypertensionPhase 3ClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0005080
bacterial infectious diseaseApprovalATC and TTD20https://conductscience.org/library/drugs?q=MONDO_0005113
eye infectionApprovalATC10https://conductscience.org/library/drugs?q=EFO_1001888

Trials18

Trials whose record names the drug by a name ChEMBL states, posted results first, then the largest. Open Targets read each trial's text to find its drugs.

TrialTitlePhaseParticipantsResults first postedNamed asLinked bySource
NCT07436104Mortality Control Program for Economically Productive Age Group in Tribal Area of Melghat.Phase 472,564norfloxacinIts nameClinicalTrials.gov
NCT03506256Noroxin Efficacy and Safety TrialPhase 41,000norfloxacinIts nameClinicalTrials.gov
NCT04159870Rifaximin Versus Norfloxacin in Spontaneous Bacterial PeritonitisPhase 3322norfloxacinIts nameClinicalTrials.gov
NCT01037959Norfloxacin Therapy for Patients With Cirrhosis and Severe Liver FailurePhase 3291norfloxacinIts nameClinicalTrials.gov
NCT06199843Efficacy of Rifaximin vs Norfloxacin for Secondary Prophylaxis of SBP (NORRIF Trial)280norfloxacinIts nameClinicalTrials.gov
NCT01039545Symptomatic Therapy of Uncomplicated Lower Urinary Tract Infections in the Ambulatory Setting.Phase 4253norfloxacinIts nameClinicalTrials.gov
NCT03695705Rifaximin and Norfloxacin for Prevention of SBP in Adults With Decompensated CirrhosisPhase 3142norfloxacinIts nameClinicalTrials.gov
NCT01542801Norfloxacin Versus Ciprofloxacin for Spontaneous Bacterial Peritonitis (SBP) PreventionPhase 4124norfloxacinIts nameClinicalTrials.gov
NCT03702426Comparison of the Efficacy of Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) and Norfloxacin in Secondary Prophylaxis for Spontaneous Bacterial Peritonitis120norfloxacinIts nameClinicalTrials.gov
NCT00947336Evaluation of Safety & Efficacy of Synbiotic on the Incidence and Recurrence of Spontaneous Bacterial Peritonitis (SBP) in CirrhoticsPhase 3110norfloxacinIts nameClinicalTrials.gov

1 to 10 of 18

See all 18 trials

Comparisons in its trials0

Comparisons Trial comparisons calculated in the trials whose record names the drug, most participants first. A comparison in one of its trials does not always compare the drug, so read the two groups.

None in this release.

Papers from its trials17

The papers the trials whose record names the drug list on ClinicalTrials.gov as their results (RESULT) or as drawn from them (DERIVED), results first, newest first.

PMIDListed asTrials listing itSource
30920712RESULT1PubMed
30246636RESULT1PubMed
29427501RESULT1PubMed
28994123RESULT1PubMed
20816858RESULT1PubMed
20633946RESULT1PubMed
17854593RESULT1PubMed
11786970RESULT1PubMed
10453941RESULT1PubMed
9764990RESULT1PubMed

Tests in its trials0

The tests ConductCognition runs that the trials whose record names the drug name in their registered outcomes, as ScienceGraph matched them. ConductCognition's list names the tests it runs, not every test a trial used.

None in this release.

Data dates

The date of each source this release read.

Open Targets
2026-09-18
Open Targets
ClinicalTrials.gov
2026-11-05
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
Papers the trials list, from Trials
2026-11-12
Trials
Comparisons, from Trial comparisons
2026-03-23
Trial comparisons
Tests named in the trials, as ScienceGraph matched them
2026-11-12
ConductCognition

Sources 7

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ConductCognition's list of its testsOur own data
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ConductCognition's list of its testsOur own data: ConductCognition's list of its tests, https://conductcognition.com
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this drug from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/drugs/v1/CHEMBL9

GET https://conductscience.org/api/drugs/v1/CHEMBL9/targets