Gene · 1001
CDH3: cadherin 3
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. CDH3: cadherin 3. Genes, record 1001. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1001
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P22223 | Cadherin-3 | 829 | 19 | Ensembl, GeneID, HGNC |
Source UniProt
Patents165
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| WO 2026210031 A1 | 2026-10-08 | 1170 | P22223 | Espacenet |
| JP 2026515744 A | 2026-05-19 | 253 | P22223 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 39468 | P22223 | Espacenet |
| JP 2025183333 A | 2025-12-16 | 74 | P22223 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 2285 | P22223 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 870 | P22223 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 870 | P22223 | Espacenet |
| JP 2025523031 A | 2025-07-17 | 98 | P22223 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 2285 | P22223 | Espacenet |
| JP 2025517332 A | 2025-06-05 | 74 | P22223 | Espacenet |
1 to 10 of 165
See all 165 patentsDrugs1
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
| Drug | ChEMBL ID | Mechanism | Action |
|---|---|---|---|
| PF-03732010 | CHEMBL2109534 | Cadherin-3 inhibitor | INHIBITOR |
Source ChEMBL
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants963
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | CDH3 papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 22 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 8 | 2025 |
| P20GM103442 | ND INBRE Health & the Environment | 4 | 2025 |
| P30CA016086 | Cancer Center Support Grant | 4 | 2025 |
| P30DK063491 | Diabetes Research Center (DRC) | 4 | 2025 |
| P30CA076292 | Moffitt Cancer Center Support Grant | 3 | 2025 |
| P30DK020572 | Michigan Diabetes Research Center (MDRC) | 3 | 2025 |
| P30ES017885 | Michigan Center on Lifestage Environmental Exposures and Disease (M-LEEaD) | 3 | 2025 |
| P50CA058223 | SPORE in Breast Cancer | 3 | 2025 |
| R01CA254060 | Leader cell development and function in Breast Tumor Collective Migration | 3 | 2025 |
1 to 10 of 963Source NIH's project files
See all 963 nih grantsPapers1,556
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| First CDH3-related HJMD case in a black patient: novel variants and diagnostic odyssey. | Ophthalmic Genet | 2026 | 42675022 | PubTator, text mining | PubMed |
| Multi-Omics Integration Identifies a CDH3-Associated Malignant Epithelial State and Immunosuppressive Niche to Predict Prognosis in Thymic Epithelial Tumors. | Adv Sci (Weinh) | 2026 | 42603286 | PubTator, text mining | PubMed |
| CDH3 Retinopathy: Long-Term Multimodal Follow-Up with Pediatric Multidisciplinary Insights. | J Clin Med | 2026 | 42513307 | PubTator, text mining | PubMed |
| CDH3 in human tumors: tumor biology and potential therapeutic target. | Front Pharmacol | 2026 | 42440815 | PubTator, text mining | PubMed |
| Cadherin-mediated cell adhesion networks drive tumor growth and therapeutic responses in head and neck cancer. | World J Surg Oncol | 2026 | 42421103 | PubTator, text mining | PubMed |
| Cell-cell junction gene signatures as subtype-specific prognostic biomarkers in breast cancer. | PLoS One | 2026 | 42371976 | PubTator, text mining | PubMed |
| Novel Compound Heterozygous Variants in CDH3 Cause Congenital Hypotrichosis with Juvenile Macular Dystrophy: A Case Report with Longitudinal Imaging and Functional Validation. | Case Rep Ophthalmol | 2026 | 42199197 | PubTator, text mining | PubMed |
| AI-Guided De Novo Design of a Caffeine-Induced Protein Dissociation System. | J Am Chem Soc | 2026 | 42184340 | PubTator, text mining | PubMed |
| Oil degradation potential and preliminary genomic insights of Pseudomonas veronii strain KHB2.9 isolated from oil-contaminated coastal soil. | Braz J Biol | 2026 | 42138876 | PubTator, text mining | PubMed |
| CDH3 Mutation in Saudi Arabia: A Case of Hypotrichosis With Juvenile Macular Dystrophy. | Cureus | 2026 | 42109964 | PubTator, text mining | PubMed |
1 to 10 of 1,556
See all 1,556 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/1001
GET https://conductscience.org/api/genes/v1/1001/patents?page=2