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Gene · 1001

CDH3: cadherin 3

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CDH3: cadherin 3. Genes, record 1001. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1001

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Gene

Symbol
CDH3
HGNC
Name
cadherin 3
HGNC
NCBI Gene ID
1001
NCBI Gene
HGNC ID
HGNC:1762
HGNC
Ensembl
ENSG00000062038
NCBI Gene
Aliases
CDHP, HJMD, PCAD
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P22223Cadherin-382919Ensembl, GeneID, HGNC

Source UniProt

Patents165

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
WO 2026210031 A12026-10-081170P22223Espacenet
JP 2026515744 A2026-05-19253P22223Espacenet
JP 2026004568 A2026-01-1439468P22223Espacenet
JP 2025183333 A2025-12-1674P22223Espacenet
EP 4650780 A22025-11-192285P22223Espacenet
JP 2025529142 A2025-09-04870P22223Espacenet
US 12371689 B22025-07-29870P22223Espacenet
JP 2025523031 A2025-07-1798P22223Espacenet
JP 2025517970 A2025-06-122285P22223Espacenet
JP 2025517332 A2025-06-0574P22223Espacenet

1 to 10 of 165

See all 165 patents

Drugs1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismAction
PF-03732010CHEMBL2109534Cadherin-3 inhibitorINHIBITOR

Source ChEMBL

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants963

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCDH3 papersNewest fiscal year
P30CA016672Cancer Center Support Grant222025
P30CA008748Cancer Center Support Grant82025
P20GM103442ND INBRE Health & the Environment42025
P30CA016086Cancer Center Support Grant42025
P30DK063491Diabetes Research Center (DRC)42025
P30CA076292Moffitt Cancer Center Support Grant32025
P30DK020572Michigan Diabetes Research Center (MDRC)32025
P30ES017885Michigan Center on Lifestage Environmental Exposures and Disease (M-LEEaD)32025
P50CA058223SPORE in Breast Cancer32025
R01CA254060Leader cell development and function in Breast Tumor Collective Migration32025

1 to 10 of 963Source NIH's project files

See all 963 nih grants

Papers1,556

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
First CDH3-related HJMD case in a black patient: novel variants and diagnostic odyssey.Ophthalmic Genet202642675022PubTator, text miningPubMed
Multi-Omics Integration Identifies a CDH3-Associated Malignant Epithelial State and Immunosuppressive Niche to Predict Prognosis in Thymic Epithelial Tumors.Adv Sci (Weinh)202642603286PubTator, text miningPubMed
CDH3 Retinopathy: Long-Term Multimodal Follow-Up with Pediatric Multidisciplinary Insights.J Clin Med202642513307PubTator, text miningPubMed
CDH3 in human tumors: tumor biology and potential therapeutic target.Front Pharmacol202642440815PubTator, text miningPubMed
Cadherin-mediated cell adhesion networks drive tumor growth and therapeutic responses in head and neck cancer.World J Surg Oncol202642421103PubTator, text miningPubMed
Cell-cell junction gene signatures as subtype-specific prognostic biomarkers in breast cancer.PLoS One202642371976PubTator, text miningPubMed
Novel Compound Heterozygous Variants in CDH3 Cause Congenital Hypotrichosis with Juvenile Macular Dystrophy: A Case Report with Longitudinal Imaging and Functional Validation.Case Rep Ophthalmol202642199197PubTator, text miningPubMed
AI-Guided De Novo Design of a Caffeine-Induced Protein Dissociation System.J Am Chem Soc202642184340PubTator, text miningPubMed
Oil degradation potential and preliminary genomic insights of Pseudomonas veronii strain KHB2.9 isolated from oil-contaminated coastal soil.Braz J Biol202642138876PubTator, text miningPubMed
CDH3 Mutation in Saudi Arabia: A Case of Hypotrichosis With Juvenile Macular Dystrophy.Cureus202642109964PubTator, text miningPubMed

1 to 10 of 1,556

See all 1,556 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/1001

GET https://conductscience.org/api/genes/v1/1001/patents?page=2