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SH2B3: SH2B adaptor protein 3
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Gene · 10019

Papers2,160

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

1 to 20 of 2,160

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TitleJournalYearPMIDFound bySource
SH2B3 Promotes PD-L1-Mediated Immune Evasion in Glioblastoma via BRCC3-Dependent IGF2BP2 Stabilization.Int J Biol Sci202642807322PubTator, text miningPubMed
LNK expression, subcellular localisation and survival associations in breast, cervical and colorectal cancer.Biomol Biomed202642751986PubTator, text miningPubMed
The bioinformatics approach to identifying pathogenic variants for colorectal cancer (CRC).J Genet Eng Biotechnol202642749394PubTator, text miningPubMed
The Germline SH2B3rs111340708 Splicing Variant Drives Intron Retention and Protein Instability by Impacting Clinical Outcomes in Core Binding Factor AML.Hematol Oncol202642731102PubTator, text miningPubMed
Age as a core disease modifier: Distinct clinical, molecular and prognostic landscapes of essential thrombocythaemia in adolescents and young adults.Br J Haematol202642698068PubTator, text miningPubMed
Beyond triple-negative: germline MPL and SH2B3/LNK mutations reshape the genetic landscape of hereditary thrombocytosis.Haematologica202642622095PubTator, text miningPubMed
Post-Treatment Persistent Erythrocytosis in Patients with Hodgkin Lymphoma: Molecular Mechanisms Underlying the Pathogenesis of Erythrocytosis.Cancers (Basel)202642588719PubTator, text miningPubMed
LNK1/2 mediate circadian-gated thermotolerance by regulating ROS homeostasis and activating HSFA8-dependent feedback to maintain temperature compensation.Plant Commun202642522196PubTator, text miningPubMed
The masquerade of motives: the immunophenotypic ambiguity in acute leukemias of ambiguous lineage, not otherwise specified.Lab Med202642492073PubTator, text miningPubMed
Genome-wide cross-trait analysis reveals immunogenetic pleiotropy between autoimmune diseases and myocardial infarction and prioritizes therapeutic targets.Atherosclerosis202642462659PubTator, text miningPubMed
Genetic screening of triple negative thrombocytosis patients identifies germline MPL compound mutations and SH2B3/LNK truncating mutations.Haematologica202642421631PubTator, text miningPubMed
Deep Dive into Evolution: How Cetaceans Adapt Their Anticoagulant Genes for Underwater Survival.J Mol Evol202642406052PubTator, text miningPubMed
A Hidden Driver Mutation in Myeloproliferative Neoplasms: SH2B3 and Diagnostic Implications and Response to Ropeginterferon Alfa-2b.J Investig Med High Impact Case Rep202642351351PubTator, text miningPubMed
Investigating the shared genetic architecture between selective immunoglobulin A deficiency and autoimmune diseases.Hum Genet202642329450PubTator, text miningPubMed
Population Genomics Insights into Pharmacogenomic Differentiation Between East Asians and Europeans.Clin Pharmacol Ther202642233542PubTator, text miningPubMed
Cytokine receptor and JAK/STAT pathway mutations in acute myeloid leukemia: Prevalence and clinical impact.Cancer202642175603PubTator, text miningPubMed
[Myeloproliferative neoplasm with a homozygous germline SH2B3 mutation: a case report and literature review].Zhonghua Xue Ye Xue Za Zhi202642161666PubTator, text miningPubMed
CCR1 as a potential regulator of neutrophil-mediated pathogenesis in post-acute ischemic stroke: a multi-omics Mendelian randomization.Clin Epigenetics202642062857PubTator, text miningPubMed
Genetic Variants Associated with Life Expectancy in Patients with Chagas Disease.Med Sci (Basel)202641892852PubTator, text miningPubMed
Interferon signaling gene expression, and DNA methylation interactions in Sjögren's disease via mendelian randomization.iScience202641858889PubTator, text miningPubMed

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Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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