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Gene · 10020

GNE: glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase

11 sourcesgene-search-2026-11-11-0.1.0

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ConductScience Library. GNE: glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase. Genes, record 10020. Release gene-search-2026-11-11-0.1.0, 11 Nov 2026. https://conductscience.org/library/genes/10020

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Gene

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

Symbol
GNE
HGNC
Name
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
HGNC
NCBI Gene ID
10020
NCBI Gene
HGNC ID
HGNC:23657
HGNC
Ensembl
ENSG00000159921
NCBI Gene
Aliases
DMRV, GLCNE, IBM2, NM, THC12, Uae1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9Y223Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase7225Ensembl, GeneID, HGNC

Source UniProt

Patents61

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026520816 A2026-06-252Q9Y223Espacenet
JP 2026067851 A2026-04-21418Q9Y223Espacenet
JP 2026067872 A2026-04-2193Q9Y223Espacenet
JP 2026004568 A2026-01-1447628Q9Y223Espacenet
JP 2026004568 A2026-01-1447631Q9Y223Espacenet
EP 4650780 A22025-11-1916031Q9Y223Espacenet
EP 4641201 A22025-10-2919420Q9Y223Espacenet
EP 4636080 A12025-10-223Q9Y223Espacenet
JP 2025529142 A2025-09-041745Q9Y223Espacenet
US 12371689 B22025-07-291745Q9Y223Espacenet

1 to 10 of 61

See all 61 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,958

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal year
ZIAHG000215Human Biochemical Genetics262025
P30AI036214San Diego Center for AIDS Research (SD CFAR)112025
P30CA008748Cancer Center Support Grant112025
RM1HG008935Center for dynamic RNA epitranscriptomes - Renewal62025
P30CA068485Cancer Center Support Grant52025
R01CA227942Targeting the cancer glycocalyx52025
R01DC009645A Collaborative Search for New Genes for Non-Syndromic Deafness52025
UL1TR001863Yale Clinical and Translational Science Award52025
P30CA086862Cancer Center Support Grant42025
R01DK099551New Congenital Disorders of Glycosylation: Therapy and Models42025

1 to 10 of 1,958Source NIH's project files

See all 1,958 nih grants

Papers4,261

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42765360PubTator, text miningPubMed
42739572PubTator, text miningPubMed
42726290PubTator, text miningPubMed
42707522PubTator, text miningPubMed
42633458PubTator, text miningPubMed
42618733PubTator, text miningPubMed
42600696PubTator, text miningPubMed
42511681PubTator, text miningPubMed
42501775PubTator, text miningPubMed
42472049PubTator, text miningPubMed

1 to 10 of 4,261

See all 4,261 papers

Sources 11

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNone stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GeneNone named. Public domain as US government information
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/10020

GET https://conductscience.org/api/genes/v1/10020/patents?page=2