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Gene · 10021

Papers1,759

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Interleukin-6 Modulates the Expression and Function of HCN Channels: A Link Between Inflammation and Atrial Electrogenesis.Int J Mol Sci202439596280PubTator, text miningPubMed
More is Different in mTORopathies.Epilepsy Curr202439508022PubTator, text miningPubMed
Analysis of epilepsy-associated variants in HCN3 - Functional implications and clinical observations.Epilepsia Open202439361439PubTator, text miningPubMed
Thyroid Hormone Receptors in Control of Heart Rate.Endocrinology202439047059PubTator, text miningPubMed
Stem cell-derived cardiomyocytes expressing a dominant negative pacemaker HCN4 channel do not reduce the risk of graft-related arrhythmias.Front Cardiovasc Med202439045008PubTator, text miningPubMed
Structural determinants of ivabradine block of the open pore of HCN4.Proc Natl Acad Sci U S A202438917012PubTator, text miningPubMed
High-Resolution Proteomics Unravel a Native Functional Complex of Cav1.3, SK3, and Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels in Midbrain Dopaminergic Neurons.Cells202438891076PubTator, text miningPubMed
Empowering artificial intelligence in characterizing the human primary pacemaker of the heart at single cell resolution.Sci Rep202438890395PubTator, text miningPubMed
Genetic and polygenic investigation of heart rate variability to identify biomarkers associated with Anxiety disorders.Psychiatry Res202438850888PubTator, text miningPubMed
Anisotropic Network Analysis of Open/Closed HCN4 Channel Advocates Asymmetric Subunit Cooperativity in cAMP Modulation of Gating.J Chem Inf Model202438830626PubTator, text miningPubMed
TBX3 transfection and nodal signal pathway inhibition promote differentiation of adipose mesenchymal stem cell to cardiac pacemaker-like cells.Stem Cell Res Ther202438778426PubTator, text miningPubMed
Pacemaker Channels and the Chronotropic Response in Health and Disease.Circ Res202438723033PubTator, text miningPubMed
LRMP inhibits cAMP potentiation of HCN4 channels by disrupting intramolecular signal transduction.Elife202438652113PubTator, text miningPubMed
Cannabidiol potentiates hyperpolarization-activated cyclic nucleotide-gated (HCN4) channels.J Gen Physiol202438652080PubTator, text miningPubMed
Replacing Animal Testing with Stem Cell-Organoids : Advantages and Limitations.Stem Cell Rev Rep202438639829PubTator, text miningPubMed
Missing validation of key features in HCN single-channel recordings.Proc Natl Acad Sci U S A202438588429PubTator, text miningPubMed
Reply to Benndorff and DiFrancesco: Reliable human HCN4 single-channel recordings using the cell-attached configuration in expression systems.Proc Natl Acad Sci U S A202438588416PubTator, text miningPubMed
Partial Resistance to Thyroid Hormone-Induced Tachycardia and Cardiac Hypertrophy in Mice Lacking Thyroid Hormone Receptor β.Thyroid202438526409PubTator, text miningPubMed
Ectopic HCN4 Provides a Target Biomarker for the Genetic Spectrum of mTORopathies.Neurol Genet202438496361PubTator, text miningPubMed
Coexistent HCN4 and GATA5 Rare Variants and Atrial Fibrillation in a Large Spanish Family.Can J Cardiol202438432398PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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