Gene · 100329167
AAA1: aortic aneurysm, familial abdominal 1
12 sourcesgene-search-2026-11-11-0.2.0
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ConductScience Library. AAA1: aortic aneurysm, familial abdominal 1. Genes, record 100329167. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/100329167
On this page
Gene
- Symbol
- AAA1
- Name
- aortic aneurysm, familial abdominal 1
- NCBI Gene ID
- 100329167
- Aliases
- AAA
- Type
- unknown
Source NCBI Gene
Proteins0
Reviewed human proteins whose Swiss-Prot entry states the gene.
None in this release.
Patents0
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
None in this release.
Drugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,171
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | AAA1 papers | Newest fiscal year |
|---|---|---|---|
| R35GM130234 | Chemical Biology of Cell Division | 9 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 6 | 2025 |
| ZIABC010600 | AAA Proteins, Mechanisms of Their Functions and Related Diseases | 6 | 2025 |
| P30ES006694 | Southwest Environmental Health Sciences Center | 5 | 2025 |
| R01GM098469 | Molecular Mechanism of the Cytoplasmic Dynein-Dynactin Motor Complex | 5 | 2025 |
| R01NS095892 | IMPACTING MITOCHONDRIAL FUNCTION THROUGH ALTERED PROTEASE ACTIVITY | 4 | 2025 |
| R35GM136414 | The Mechanism and Regulation of the Dynein Transport Machinery | 4 | 2025 |
| ZIALM000061 | Finding Protein Sequence Motifs--Methods And Applications | 4 | 2025 |
| ZIALM000073 | Comparative Analysis Of Completely Sequenced Genomes | 4 | 2025 |
| P30CA016056 | Roswell Park Cancer Center Support Grant | 3 | 2025 |
1 to 10 of 1,171Source NIH's project files
See all 1,171 nih grantsPapers1,791
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Tied to Work: Topologically Knotted SPOUT Methyltransferases and UCH Deubiquitinases in Cellular Biochemistry. | J Cell Biochem | 2026 | 42751996 | PubTator, text mining | PubMed |
| Distinct tubulin C-terminal tails control the efficiency of a microtubule severing machine. | J Chem Phys | 2026 | 42746985 | PubTator, text mining | PubMed |
| Induced degradation of Ufd1 reveals regulation of cohesin by the VCP/p97Ufd1-Npl4 complex. | Life Sci Alliance | 2026 | 42692794 | PubTator, text mining | PubMed |
| Asymmetry and Allostery: Insights into the Mechanism of Directional Peptide Translocation in AAA+ Unfoldases. | bioRxiv | 2026 | 42619752 | PubTator, text mining | PubMed |
| External validation of the AAA+ survival model in a large Chinese cohort with essential thrombocythaemia. | Br J Haematol | 2026 | 42613014 | PubTator, text mining | PubMed |
| FAF1 and FAF2 enhance unfolding by p97-UFD1-NPL4 complex enabling rational design of p97 activators. | EMBO J | 2026 | 42603836 | PubTator, text mining | PubMed |
| A regulatory adaptor for RAD51's AAA+ unfoldase promotes homologous recombination-mediated DNA repair and genome stability. | Proc Natl Acad Sci U S A | 2026 | 42594276 | PubTator, text mining | PubMed |
| Mechanistic diversity of clamp loading at small DNA gaps. | J Biol Chem | 2026 | 42575442 | PubTator, text mining | PubMed |
| Structural divergence in N-terminal domains of AAA proteases paraplegin (SPG7) and FtsH indicates a key structural function in complex formation. | J Struct Biol | 2026 | 42546997 | PubTator, text mining | PubMed |
| Electrostatic steering in integrin recognition revealed by a programmable heterotrimeric collagen platform. | Int J Biol Macromol | 2026 | 42526560 | PubTator, text mining | PubMed |
1 to 10 of 1,791
See all 1,791 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
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The record and each of its lists are JSON, twenty rows a page. No key.
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