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Gene · 10038

Papers2,674

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

101 to 120 of 2,674

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TitleJournalYearPMIDFound bySource
Maintenance with niraparib in patients with stage III, stage IV, chemo-naïve recurrent or platinum-sensitive recurrent uterine serous carcinoma: study protocol for a phase II clinical trial.BMJ Open202540473279PubTator, text miningPubMed
Approaches to repurposing reverse transcriptase antivirals in cancer.Br J Clin Pharmacol202540432477PubTator, text miningPubMed
Widespread false negatives in DNA-encoded library data: how linker effects impair machine learning-based lead prediction.Chem Sci202540395382PubTator, text miningPubMed
Adenosine diphosphate-ribosylation greatly affects proteins function: a focus on neurodegenerative diseases.Front Aging Neurosci202540370754PubTator, text miningPubMed
Joining of DNA breaks- interplay between DNA ligases and poly (ADP-ribose) polymerases.DNA Repair (Amst)202540347914PubTator, text miningPubMed
Identification of hub genes related to DNA damage response in asthma via combinative bioinformatics strategy.J Int Med Res202540288048PubTator, text miningPubMed
Trabectedin Induces Synthetic Lethality via the p53-Dependent Apoptotic Pathway in Ovarian Cancer Cells Without BRCA Mutations When Used in Combination with Niraparib.Int J Mol Sci202540243501PubTator, text miningPubMed
Engaging an engineered PARP-2 catalytic domain mutant to solve the complex structures harboring approved drugs for structure analyses.Bioorg Chem202540228437PubTator, text miningPubMed
Prognostic Value of PARP1 and PARP2 Copy Number Alterations in Prostate Cancer.Lab Invest202540210166PubTator, text miningPubMed
Employing a Highly Potent Fluorescence Probe to Discover a Poly (Adenosine Diphosphate-ribose) Polymerases-1/2 Binder and the Complex Structures Analysis.ChemMedChem202540204633PubTator, text miningPubMed
PARP inhibitors in ovarian cancer: Mechanisms of resistance and implications to therapy.DNA Repair (Amst)202540203475PubTator, text miningPubMed
HPF1 Regulates Pol β Efficiency in Nucleosomes via the Modulation of Total Poly(ADP-Ribose) Synthesis.Int J Mol Sci202540076422PubTator, text miningPubMed
PARP2 Catalytic Activity Is Allosterically Stimulated by Binding to the c-KIT1 G-Quadruplex.ACS Omega202540060879PubTator, text miningPubMed
PARP-2 acts on ILK signaling and pharmacological targeting of PARP-2 ameliorate endometriosis in a mouse model.Biochem Biophys Res Commun202540036901PubTator, text miningPubMed
Duplexed CeTEAM drug biosensors reveal determinants of PARP inhibitor selectivity in cells.J Biol Chem202540021124PubTator, text miningPubMed
XRCC1 mediates PARP1- and PAR-dependent recruitment of PARP2 to DNA damage sites.Nucleic Acids Res202539970298PubTator, text miningPubMed
Parps in immune response: Potential targets for cancer immunotherapy.Biochem Pharmacol202539965743PubTator, text miningPubMed
Regulatory and Catalytic Domains of Poly(ADP-ribose) Polymerases Cross-Complement for DNA-Break-Dependent Allosteric Stimulation of Catalytic Activity.ACS Chem Biol202539935093PubTator, text miningPubMed
Multi-stage structure-based virtual screening approach combining 3D pharmacophore, docking and molecular dynamic simulation towards the identification of potential selective PARP-1 inhibitors.BMC Chem202539893479PubTator, text miningPubMed
A PARP2 active site helix melts to permit DNA damage-induced enzymatic activation.Mol Cell202539889708PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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