Gene · 10049
DNAJB6: DnaJ heat shock protein family (Hsp40) member B6
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. DNAJB6: DnaJ heat shock protein family (Hsp40) member B6. Genes, record 10049. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10049
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| O75190 | DnaJ homolog subfamily B member 6 | 326 | 4 | Ensembl, GeneID, HGNC |
Source UniProt
Patents30
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 44107 | O75190 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 2026 | O75190 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 1590 | O75190 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 1590 | O75190 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 2026 | O75190 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 27387 | O75190 | Espacenet |
| EP 4484957 A1 | 2025-01-01 | 128 | O75190 | Espacenet |
| EP 4461818 A2 | 2024-11-13 | 27387 | O75190 | Espacenet |
| WO 2023162878 A | 2023-08-31 | 128 | O75190 | Espacenet |
| JP 2023058610 A | 2023-04-25 | 27387 | O75190 | Espacenet |
1 to 10 of 30
See all 30 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,554
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | DNAJB6 papers | Newest fiscal year |
|---|---|---|---|
| R01NS059690 | Molecular Chaperones and Small Molecules | 15 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 12 | 2025 |
| R01AR068797 | Chaperone Dysfunction in Myopathy: Connecting Yeast Genetics with Mouse Models | 11 | 2025 |
| R01HL107304 | Epicardial remodeling in cardiomyopathy and cardiac aging | 8 | 2025 |
| K24AR073317 | Clinical and Translational studies in muscle disease | 7 | 2025 |
| R01HL081753 | Genetic Studies of Sarcomere-based Cardiac Diseases | 7 | 2025 |
| R01NS073899 | The hsp90 Cochaperone FKBP51 Regulates tau Structure and Function | 7 | 2025 |
| R01AG031867 | Protein aggregation in inclusion body and myofibrillar myopathies | 6 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 5 | 2025 |
| P30CA021765 | Cancer Center Support Grant (CCSG) | 5 | 2025 |
1 to 10 of 1,554Source NIH's project files
See all 1,554 nih grantsPapers2,435
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| PTBP1-Mediated Alternative Splicing of DNAJB6 Promotes Everolimus Resistance in Clear Cell Renal Cell Carcinoma via EIF4B/PKIB/AKT/mTOR Positive Feedback Loop. | Adv Sci (Weinh) | 2026 | 42801686 | PubTator, text mining | PubMed |
| A Novel Plate Reader-Based Protocol for Measurement of DNAJB6 Dimerization Activity. | Bio Protoc | 2026 | 42577708 | PubTator, text mining | PubMed |
| Accurate interdomain contacts in a mixed folded protein from NMR-guided coarse-grained simulations. | Phys Chem Chem Phys | 2026 | 42370432 | PubTator, text mining | PubMed |
| Small bites for big problems: stepwise aggregate degradation by autophagy. | Biochem Soc Trans | 2026 | 42325197 | PubTator, text mining | PubMed |
| Interacting proteins of AMPK studied using TurboID proximity labeling technology. | Exp Ther Med | 2026 | 42022757 | PubTator, text mining | PubMed |
| Microplastic-induced transcriptional stress in the filter-feeding ciliate Stentor coeruleus: A novel avenue for understanding unicellular responses. | Eur J Protistol | 2026 | 41996776 | PubTator, text mining | PubMed |
| Transient Aggregation-Prone States in Disordered Proteins as Therapeutic Targets: The Amyloid-β Case. | J Chem Inf Model | 2026 | 41981770 | PubTator, text mining | PubMed |
| Hsp70 diversification and repurposing across the tree of life: Lessons from the evolutionary and mechanistic trajectory of the Hsp70-Hsp110 chaperone system. | FEBS J | 2026 | 41981728 | PubTator, text mining | PubMed |
| Misfolded Proteins and Cognitive Decline: Mechanistic Insights into Neurodegenerative Disorders. | Neurol Int | 2026 | 41893050 | PubTator, text mining | PubMed |
| Advances in the biological functions of miR‑205 in various diseases (Review). | Mol Med Rep | 2026 | 41860043 | PubTator, text mining | PubMed |
1 to 10 of 2,435
See all 2,435 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/10049
GET https://conductscience.org/api/genes/v1/10049/patents?page=2