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Gene · 100529063

BCL2L2-PABPN1: BCL2L2-PABPN1 readthrough

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. BCL2L2-PABPN1: BCL2L2-PABPN1 readthrough. Genes, record 100529063. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/100529063

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Gene

Symbol
BCL2L2-PABPN1
HGNC
Name
BCL2L2-PABPN1 readthrough
HGNC
NCBI Gene ID
100529063
NCBI Gene
HGNC ID
HGNC:42959
HGNC
Ensembl
ENSG00000258643
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q92843Bcl-2-like protein 21935Ensembl, HGNC

Source UniProt

Patents23

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-191309Q92843Espacenet
JP 2025529142 A2025-09-04571Q92843Espacenet
US 12371689 B22025-07-29571Q92843Espacenet
JP 2025517970 A2025-06-121309Q92843Espacenet
JP 2025062604 A2025-04-148854Q92843Espacenet
JP 2024123008 A2024-09-105062Q92843Espacenet
US 11708396 B22023-07-251439Q92843Espacenet
US 11446398 B22022-09-208854Q92843Espacenet
JP 2022524081 A2022-04-27111825Q92843Espacenet
WO 2020043864 A12020-03-05281Q92843Espacenet

1 to 10 of 23

See all 23 patents

Drugs3

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
NAVITOCLAXCHEMBL443684Apoptosis regulator Bcl-W inhibitorINHIBITORChEMBL
OBATOCLAXCHEMBL408194Apoptosis regulator Bcl-W inhibitorINHIBITORChEMBL
OBATOCLAX MESYLATECHEMBL2107358Apoptosis regulator Bcl-W inhibitorINHIBITORChEMBL

Trials55

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT06210750NAVITOCLAXPHASE2ClinicalTrials.gov
NCT06007911NAVITOCLAXPHASE1ClinicalTrials.gov
NCT05864742NAVITOCLAXPHASE2ClinicalTrials.gov
NCT05740449NAVITOCLAXPHASE1/PHASE2ClinicalTrials.gov
NCT05564650NAVITOCLAXPHASE1ClinicalTrials.gov
NCT05455294NAVITOCLAXPHASE1ClinicalTrials.gov
NCT05358639NAVITOCLAXPHASE1ClinicalTrials.gov
NCT05222984NAVITOCLAXPHASE1ClinicalTrials.gov
NCT05215405NAVITOCLAXClinicalTrials.gov
NCT05192889NAVITOCLAXPHASE1/PHASE22025-09-22ClinicalTrials.gov

1 to 10 of 55

See all 55 trials

NIH grants34

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleBCL2L2-PABPN1 papersNewest fiscal year
P30CA015704Cancer Center Support Grant12025
R01AG050986Higher Order Chromatin and Genetic Risk for Alzheimer's Disease12025
R01CA207513Role of KLHL6 inactivation in mature B-cell malignancies12025
R01HL109557Mechanisms and Consequences of Gene Induction by Glucocorticoids in Airway Smooth Muscle12025
R37CA252050Understanding and exploiting novel therapeutic vulnerabilities of RIT1-driven lung cancer12025
T32HL007085Multi-Disciplinary Research Training in Respiratory Disease12025
R01GM067945New Sample Multiplexing Technologies to Identify Chemical Probes and Illuminate Ubiquitin Biology12024
U01HG007690Center for Integrated Approached to Undiagnosed Diseases12022
R01GM125871A Technique for Measuring Transcription Factor Activity12021
R35GM124766Mechanisms regulating nuclear envelope structure and stability12021

1 to 10 of 34Source NIH's project files

See all 34 nih grants

Papers28

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Deconvolution of multiplexed transcriptional responses to wood smoke particles defines rapid aryl hydrocarbon receptor signaling dynamics.J Biol Chem202134520756PubTator, text miningPubMed
Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer.Nat Commun202134373451PubTator, text miningPubMed
Transcript-Level Dysregulation of BCL2 Family Genes in Acute Myeloblastic Leukemia.Cancers (Basel)202134202143PubTator, text miningPubMed
A reference map of the human binary protein interactome.Nature202032296183PubTator, text miningPubMed
Genome-wide CRISPR screening reveals genetic modifiers of mutant EGFR dependence in human NSCLC.Elife201931741433PubTator, text miningPubMed
DNA methylome-wide alterations associated with estrogen receptor-dependent effects of bisphenols in breast cancer.Clin Epigenetics201931601247PubTator, text miningPubMed
Metabolomics Associated with Genome-Wide Association Study Related to the Basal Metabolic Rate in Overweight/Obese Korean Women.J Med Food201930990731PubTator, text miningPubMed
PTPN14 regulates Roquin2 stability by tyrosine dephosphorylation.Cell Cycle201830209976PubTator, text miningPubMed
THC exposure of human iPSC neurons impacts genes associated with neuropsychiatric disorders.Transl Psychiatry201829691375PubTator, text miningPubMed
High-Density Proximity Mapping Reveals the Subcellular Organization of mRNA-Associated Granules and Bodies.Mol Cell201829395067PubTator, text miningPubMed

1 to 10 of 28

See all 28 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/100529063

GET https://conductscience.org/api/genes/v1/100529063/patents?page=2