Gene · 10057
ABCC5: ATP binding cassette subfamily C member 5
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. ABCC5: ATP binding cassette subfamily C member 5. Genes, record 10057. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10057
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| O15440 | ATP-binding cassette sub-family C member 5 | 1,437 | 6 | Ensembl, GeneID, HGNC |
Source UniProt
Patents32
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 38429 | O15440 | Espacenet |
| WO 2025252547 A1 | 2025-12-11 | 4 | O15440 | Espacenet |
| EP 4660322 A1 | 2025-12-10 | 4 | O15440 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 6056 | O15440 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 5789 | O15440 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 203 | O15440 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 203 | O15440 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 5789 | O15440 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 6056 | O15440 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 7737 | O15440 | Espacenet |
1 to 10 of 32
See all 32 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants902
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | ABCC5 papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 8 | 2025 |
| P30ES006694 | Southwest Environmental Health Sciences Center | 8 | 2025 |
| P30CA021765 | Cancer Center Support Grant (CCSG) | 7 | 2025 |
| R01DK074797 | Inter-organ signaling in heme metabolism and organismal homeostasis. | 6 | 2025 |
| P30CA006927 | Comprehensive Cancer Center Program at Fox Chase | 5 | 2025 |
| P30ES005022 | Rutgers Center for Environmental Exposure and Disease (CEED) | 5 | 2025 |
| T32ES007148 | Training in Environmental Toxicology | 4 | 2025 |
| ZIABC010627 | Clinical Pharmacogenetics | 4 | 2025 |
| P30CA118100 | University of New Mexico Cancer Center Support Grant | 3 | 2025 |
| R01DK080834 | Inhibition of an Apical cAMP/cGMP Transporter (MRP4) in the Gut Induces Diarrhea | 3 | 2025 |
1 to 10 of 902Source NIH's project files
See all 902 nih grantsPapers1,907
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Integrated network toxicology, machine learning, and multi-omics characterization of 2,4-DTBP neurotoxicity. | Chem Biol Interact | 2026 | 42822756 | PubTator, text mining | PubMed |
| Disrupting KRAS-AGO2 interaction: a dual-pronged strategy to sensitize chemo-immunotherapy in KRAS-mutated colorectal cancer. | Apoptosis | 2026 | 42622908 | PubTator, text mining | PubMed |
| A conserved vesicular circuit enables metabolic adaptation and maintains systemic heme homeostasis. | bioRxiv | 2026 | 42620181 | PubTator, text mining | PubMed |
| Interleukin-1β and Interleukin-6 Signaling Differentially Regulate ABC Transporter Activity and Amyloid-β Handling in Primary Porcine Brain Endothelial Cells. | Cells | 2026 | 42505383 | PubTator, text mining | PubMed |
| Pharmacogenetic mechanism of cilostazol-induced headaches: Splicing-mediated loss of ABCC5 gene function. | Br J Pharmacol | 2026 | 42485569 | PubTator, text mining | PubMed |
| Bis-(di-4-phenyl-benzylaminethiocarbonyl)disulfide sensitizes ABCC2/ALDH3A1 overexpressing NSCLC cells to cisplatin. | Cancer Biol Ther | 2026 | 42474358 | PubTator, text mining | PubMed |
| Pharmacogenomic profiling of the efficacy of gemcitabine monotherapy in metastatic pancreatic cancer: Subgroup analysis of the GENESECT study. | Br J Clin Pharmacol | 2026 | 42220058 | PubTator, text mining | PubMed |
| Development of liposomal pemetrexed for enhanced therapy against multidrug resistance mediated by ABCC5 in breast cancer [Retraction]. | Int J Nanomedicine | 2026 | 42205871 | PubTator, text mining | PubMed |
| Influence of inflammation on drug transporter expression in human airway epithelia: Implications for inhaled drug pharmacokinetics. | Drug Metab Dispos | 2026 | 42066732 | PubTator, text mining | PubMed |
| Stigmasterol reverses rituximab resistance in diffuse large B-cell lymphoma via the MAPK1 signaling pathway. | Transl Cancer Res | 2026 | 41969461 | PubTator, text mining | PubMed |
1 to 10 of 1,907
See all 1,907 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/10057
GET https://conductscience.org/api/genes/v1/10057/patents?page=2