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Gene · 10057

ABCC5: ATP binding cassette subfamily C member 5

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ABCC5: ATP binding cassette subfamily C member 5. Genes, record 10057. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10057

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Gene

Symbol
ABCC5
HGNC
Name
ATP binding cassette subfamily C member 5
HGNC
NCBI Gene ID
10057
NCBI Gene
HGNC ID
HGNC:56
HGNC
Ensembl
ENSG00000114770
NCBI Gene
Aliases
ABC33, EST277145, MOAT-C, MOATC, MRP5, SMRP, pABC11
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O15440ATP-binding cassette sub-family C member 51,4376Ensembl, GeneID, HGNC

Source UniProt

Patents32

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1438429O15440Espacenet
WO 2025252547 A12025-12-114O15440Espacenet
EP 4660322 A12025-12-104O15440Espacenet
EP 4650780 A22025-11-196056O15440Espacenet
EP 4641201 A22025-10-295789O15440Espacenet
JP 2025529142 A2025-09-04203O15440Espacenet
US 12371689 B22025-07-29203O15440Espacenet
JP 2025517969 A2025-06-125789O15440Espacenet
JP 2025517970 A2025-06-126056O15440Espacenet
JP 2025062604 A2025-04-147737O15440Espacenet

1 to 10 of 32

See all 32 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants902

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleABCC5 papersNewest fiscal year
P30CA016672Cancer Center Support Grant82025
P30ES006694Southwest Environmental Health Sciences Center82025
P30CA021765Cancer Center Support Grant (CCSG)72025
R01DK074797Inter-organ signaling in heme metabolism and organismal homeostasis.62025
P30CA006927Comprehensive Cancer Center Program at Fox Chase52025
P30ES005022Rutgers Center for Environmental Exposure and Disease (CEED)52025
T32ES007148Training in Environmental Toxicology42025
ZIABC010627Clinical Pharmacogenetics42025
P30CA118100University of New Mexico Cancer Center Support Grant32025
R01DK080834Inhibition of an Apical cAMP/cGMP Transporter (MRP4) in the Gut Induces Diarrhea32025

1 to 10 of 902Source NIH's project files

See all 902 nih grants

Papers1,907

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Integrated network toxicology, machine learning, and multi-omics characterization of 2,4-DTBP neurotoxicity.Chem Biol Interact202642822756PubTator, text miningPubMed
Disrupting KRAS-AGO2 interaction: a dual-pronged strategy to sensitize chemo-immunotherapy in KRAS-mutated colorectal cancer.Apoptosis202642622908PubTator, text miningPubMed
A conserved vesicular circuit enables metabolic adaptation and maintains systemic heme homeostasis.bioRxiv202642620181PubTator, text miningPubMed
Interleukin-1β and Interleukin-6 Signaling Differentially Regulate ABC Transporter Activity and Amyloid-β Handling in Primary Porcine Brain Endothelial Cells.Cells202642505383PubTator, text miningPubMed
Pharmacogenetic mechanism of cilostazol-induced headaches: Splicing-mediated loss of ABCC5 gene function.Br J Pharmacol202642485569PubTator, text miningPubMed
Bis-(di-4-phenyl-benzylaminethiocarbonyl)disulfide sensitizes ABCC2/ALDH3A1 overexpressing NSCLC cells to cisplatin.Cancer Biol Ther202642474358PubTator, text miningPubMed
Pharmacogenomic profiling of the efficacy of gemcitabine monotherapy in metastatic pancreatic cancer: Subgroup analysis of the GENESECT study.Br J Clin Pharmacol202642220058PubTator, text miningPubMed
Development of liposomal pemetrexed for enhanced therapy against multidrug resistance mediated by ABCC5 in breast cancer [Retraction].Int J Nanomedicine202642205871PubTator, text miningPubMed
Influence of inflammation on drug transporter expression in human airway epithelia: Implications for inhaled drug pharmacokinetics.Drug Metab Dispos202642066732PubTator, text miningPubMed
Stigmasterol reverses rituximab resistance in diffuse large B-cell lymphoma via the MAPK1 signaling pathway.Transl Cancer Res202641969461PubTator, text miningPubMed

1 to 10 of 1,907

See all 1,907 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/10057

GET https://conductscience.org/api/genes/v1/10057/patents?page=2