Gene · 10060
ABCC9: ATP binding cassette subfamily C member 9
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. ABCC9: ATP binding cassette subfamily C member 9. Genes, record 10060. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10060
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| O60706 | ATP-binding cassette sub-family C member 9 | 1,549 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents16
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 38441 | O60706 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 1437 | O60706 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 206 | O60706 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 206 | O60706 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 1437 | O60706 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 7765 | O60706 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 7765 | O60706 | Espacenet |
| US 11400116 B2 | 2022-08-02 | 3345 | O60706 | Espacenet |
| US 11400116 B2 | 2022-08-02 | 4624 | O60706 | Espacenet |
| US 11400116 B2 | 2022-08-02 | 4636 | O60706 | Espacenet |
1 to 10 of 16
See all 16 patentsDrugs5
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
| Drug | ChEMBL ID | Mechanism | Action | Source |
|---|---|---|---|---|
| MINOXIDIL | CHEMBL802 | Sulfonylurea receptor 2, Kir6.2 opener | OPENER | ChEMBL |
| NAMINIDIL | CHEMBL2105160 | Sulfonylurea receptors; K-ATP channels opener | OPENER | ChEMBL |
| PINACIDIL | CHEMBL1200338 | Sulfonylurea receptor 2, Kir6.2 opener | OPENER | ChEMBL |
| PINACIDIL ANHYDROUS | CHEMBL1159 | Sulfonylurea receptor 2, Kir6.2 opener | OPENER | ChEMBL |
| SARAKALIM | CHEMBL2104449 | Sulfonylurea receptors; K-ATP channels opener | OPENER | ChEMBL |
Trials55
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
| Trial | Drug | Phase | Results first posted | Source |
|---|---|---|---|---|
| NCT07594678 | MINOXIDIL | PHASE2 | ClinicalTrials.gov | |
| NCT07563036 | MINOXIDIL | ClinicalTrials.gov | ||
| NCT07548918 | MINOXIDIL | PHASE2 | ClinicalTrials.gov | |
| NCT07536100 | MINOXIDIL | ClinicalTrials.gov | ||
| NCT07529977 | MINOXIDIL | PHASE3 | ClinicalTrials.gov | |
| NCT07502976 | MINOXIDIL | ClinicalTrials.gov | ||
| NCT07435012 | MINOXIDIL | PHASE3 | ClinicalTrials.gov | |
| NCT07373054 | MINOXIDIL | ClinicalTrials.gov | ||
| NCT07273799 | MINOXIDIL | PHASE3 | ClinicalTrials.gov | |
| NCT07203599 | MINOXIDIL | PHASE1/PHASE2 | ClinicalTrials.gov |
1 to 10 of 55
See all 55 trialsNIH grants1,262
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | ABCC9 papers | Newest fiscal year |
|---|---|---|---|
| U24AG021886 | National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD) | 8 | 2025 |
| R01AG061111 | Safety and modulation of ABCC9 pathways by nicorandil for the treatment of hippocampal sclerosis of aging (SMArTâHS) | 6 | 2025 |
| P30AG072946 | University of Kentucky Alzheimer's Disease Research Center | 5 | 2025 |
| R01HL092577 | IDENTIFICATION OF COMMON GENETIC VARIANTS FOR ATRIAL FIBRILLATION AND PR INTERVAL | 5 | 2025 |
| R35HL171542 | Cardiovascular potassium channels: From molecular basis to disease therapeutics | 4 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 4 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 3 | 2025 |
| P30DK020593 | Vanderbilt Diabetes Research Center | 3 | 2025 |
| P30DK116074 | Stanford Diabetes Research Center | 3 | 2025 |
| T32GM007526 | Medical Genetics Research Fellowship Program | 3 | 2025 |
1 to 10 of 1,262Source NIH's project files
See all 1,262 nih grantsPapers1,427
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| ABCC9/SUR2 has a Complex Expression Pattern in Human Brain Gliovascular Unit Cells, Including Astrocytes. | J Mol Neurosci | 2026 | 42762395 | PubTator, text mining | PubMed |
| Pharmacological inhibition of CDK7 and CDK9 suppresses gastrointestinal (colon) cancer progression through modulation of stemness, epithelial-mesenchymal transition, and chemoresistance. | Naunyn Schmiedebergs Arch Pharmacol | 2026 | 42624930 | PubTator, text mining | PubMed |
| From Array-CGH to Whole-Genome Sequencing: A 29-Year Diagnostic Journey Culminating in the Identification of a De Novo ABCC9 Variant Consistent with Cantú Syndrome. | Diagnostics (Basel) | 2026 | 42510068 | PubTator, text mining | PubMed |
| Single-cell transcriptomics identifies key immune-suppressive cells and their driver genes in the bladder cancer microenvironment with prognostic implications. | Mol Genet Genomics | 2026 | 42319469 | PubTator, text mining | PubMed |
| Will the real KATP please stand up? Kir6.2/SUR2A takes the stand in the tiring case of skeletal muscle fatigue. | J Gen Physiol | 2026 | 42295105 | PubTator, text mining | PubMed |
| Cognitive Decline, Neurologic Involvement, and Neonatal Crisis in ABCC9-Related Intellectual Disability and Myopathy Syndrome. | Neurol Genet | 2026 | 42290677 | PubTator, text mining | PubMed |
| Uncoupling of nutrient sensing and cell size control by specific defects in ceramide structure. | Biol Open | 2026 | 42093330 | PubTator, text mining | PubMed |
| Heterogeneity characterization and key pathogenic genes screening based on diabetic nephropathy microenvironment. | Open Life Sci | 2026 | 42037662 | PubTator, text mining | PubMed |
| Biophysical Characterization of a Novel KCNJ8 Rare Variant Linked With Inherited and Acquired J Wave Syndrome. | JACC Clin Electrophysiol | 2026 | 41995661 | PubTator, text mining | PubMed |
| Research progress in heterogeneity of dental mesenchymal stem cells. | Int J Oral Sci | 2026 | 41932866 | PubTator, text mining | PubMed |
1 to 10 of 1,427
See all 1,427 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/10060
GET https://conductscience.org/api/genes/v1/10060/patents