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Gene · 10060

ABCC9: ATP binding cassette subfamily C member 9

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ABCC9: ATP binding cassette subfamily C member 9. Genes, record 10060. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10060

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Gene

Symbol
ABCC9
HGNC
Name
ATP binding cassette subfamily C member 9
HGNC
NCBI Gene ID
10060
NCBI Gene
HGNC ID
HGNC:60
HGNC
Ensembl
ENSG00000069431
NCBI Gene
Aliases
ABC37, ATFB12, CANTU, CMD1O, IDMYS, SUR2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O60706ATP-binding cassette sub-family C member 91,5490Ensembl, GeneID, HGNC

Source UniProt

Patents16

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1438441O60706Espacenet
EP 4641201 A22025-10-291437O60706Espacenet
JP 2025529142 A2025-09-04206O60706Espacenet
US 12371689 B22025-07-29206O60706Espacenet
JP 2025517969 A2025-06-121437O60706Espacenet
JP 2025062604 A2025-04-147765O60706Espacenet
US 11446398 B22022-09-207765O60706Espacenet
US 11400116 B22022-08-023345O60706Espacenet
US 11400116 B22022-08-024624O60706Espacenet
US 11400116 B22022-08-024636O60706Espacenet

1 to 10 of 16

See all 16 patents

Drugs5

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
MINOXIDILCHEMBL802Sulfonylurea receptor 2, Kir6.2 openerOPENERChEMBL
NAMINIDILCHEMBL2105160Sulfonylurea receptors; K-ATP channels openerOPENERChEMBL
PINACIDILCHEMBL1200338Sulfonylurea receptor 2, Kir6.2 openerOPENERChEMBL
PINACIDIL ANHYDROUSCHEMBL1159Sulfonylurea receptor 2, Kir6.2 openerOPENERChEMBL
SARAKALIMCHEMBL2104449Sulfonylurea receptors; K-ATP channels openerOPENERChEMBL

Trials55

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

NIH grants1,262

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleABCC9 papersNewest fiscal year
U24AG021886National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD)82025
R01AG061111Safety and modulation of ABCC9 pathways by nicorandil for the treatment of hippocampal sclerosis of aging (SMArT–HS)62025
P30AG072946University of Kentucky Alzheimer's Disease Research Center52025
R01HL092577IDENTIFICATION OF COMMON GENETIC VARIANTS FOR ATRIAL FIBRILLATION AND PR INTERVAL52025
R35HL171542Cardiovascular potassium channels: From molecular basis to disease therapeutics42025
UL1TR001863Yale Clinical and Translational Science Award42025
P30CA068485Cancer Center Support Grant32025
P30DK020593Vanderbilt Diabetes Research Center32025
P30DK116074Stanford Diabetes Research Center32025
T32GM007526Medical Genetics Research Fellowship Program32025

1 to 10 of 1,262Source NIH's project files

See all 1,262 nih grants

Papers1,427

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
ABCC9/SUR2 has a Complex Expression Pattern in Human Brain Gliovascular Unit Cells, Including Astrocytes.J Mol Neurosci202642762395PubTator, text miningPubMed
Pharmacological inhibition of CDK7 and CDK9 suppresses gastrointestinal (colon) cancer progression through modulation of stemness, epithelial-mesenchymal transition, and chemoresistance.Naunyn Schmiedebergs Arch Pharmacol202642624930PubTator, text miningPubMed
From Array-CGH to Whole-Genome Sequencing: A 29-Year Diagnostic Journey Culminating in the Identification of a De Novo ABCC9 Variant Consistent with Cantú Syndrome.Diagnostics (Basel)202642510068PubTator, text miningPubMed
Single-cell transcriptomics identifies key immune-suppressive cells and their driver genes in the bladder cancer microenvironment with prognostic implications.Mol Genet Genomics202642319469PubTator, text miningPubMed
Will the real KATP please stand up? Kir6.2/SUR2A takes the stand in the tiring case of skeletal muscle fatigue.J Gen Physiol202642295105PubTator, text miningPubMed
Cognitive Decline, Neurologic Involvement, and Neonatal Crisis in ABCC9-Related Intellectual Disability and Myopathy Syndrome.Neurol Genet202642290677PubTator, text miningPubMed
Uncoupling of nutrient sensing and cell size control by specific defects in ceramide structure.Biol Open202642093330PubTator, text miningPubMed
Heterogeneity characterization and key pathogenic genes screening based on diabetic nephropathy microenvironment.Open Life Sci202642037662PubTator, text miningPubMed
Biophysical Characterization of a Novel KCNJ8 Rare Variant Linked With Inherited and Acquired J Wave Syndrome.JACC Clin Electrophysiol202641995661PubTator, text miningPubMed
Research progress in heterogeneity of dental mesenchymal stem cells.Int J Oral Sci202641932866PubTator, text miningPubMed

1 to 10 of 1,427

See all 1,427 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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