Gene · 10096
ACTR3: actin related protein 3
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. ACTR3: actin related protein 3. Genes, record 10096. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10096
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P61158 | Actin-related protein 3 | 418 | 5 | Ensembl, GeneID, HGNC |
Source UniProt
Patents33
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| WO 2026063308 A | 2026-03-26 | 8 | P61158 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 2180 | P61158 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 2180 | P61158 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 6431 | P61158 | Espacenet |
| JP 2024123008 A | 2024-09-10 | 4891 | P61158 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 6431 | P61158 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 109402 | P61158 | Espacenet |
| US 10501513 B2 | 2019-12-10 | 4891 | P61158 | Espacenet |
| US 10190166 B2 | 2019-01-29 | 84 | P61158 | Espacenet |
| EP 3403091 A1 | 2018-11-21 | 413 | P61158 | Espacenet |
1 to 10 of 33
See all 33 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,704
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | ACTR3 papers | Newest fiscal year |
|---|---|---|---|
| R01GM073791 | Structural-Functional Basis of Actin Cytoskeleton Dynamics | 20 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 7 | 2025 |
| P30CA016086 | Cancer Center Support Grant | 7 | 2025 |
| R35GM136319 | Control of actin filament networks by Arp2/3 complex and its regulators | 6 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 5 | 2025 |
| P40OD018537 | Bloomington Drosophila Stock Center at Indiana University | 5 | 2025 |
| R35GM118119 | Assembly and function of cytoskeletal systems in eukaryotic and prokaryoticcells | 5 | 2025 |
| P01HL126609 | Cytoskeletal Regulation of Lung Endothelial Pathobiology in ARDS | 4 | 2025 |
| P20GM113132 | The Institute for Biomolecular Targeting | 4 | 2025 |
| P30CA015704 | Cancer Center Support Grant | 4 | 2025 |
1 to 10 of 1,704Source NIH's project files
See all 1,704 nih grantsPapers2,778
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Integrative WGBS and ATAC-seq profiling reveals epigenetic and chromatin accessibility signatures associated with clutch length in goose ovaries. | Poult Sci | 2026 | 42727346 | PubTator, text mining | PubMed |
| Genome-wide association study of egg numbers across different laying phases in a large-scale layer population. | Br Poult Sci | 2026 | 42615881 | PubTator, text mining | PubMed |
| Arp2/3 Inhibition Synergizes With PARP Inhibitors by Impairing Homologous Recombination in Gastric Cancer Cells. | Front Biosci (Landmark Ed) | 2026 | 42530272 | PubTator, text mining | PubMed |
| Inorganic phosphate rapidly switches the stability of Arp2/3-induced actin branches. | J Cell Biol | 2026 | 42424095 | PubTator, text mining | PubMed |
| ACTR3 enhances the hyperproliferation of psoriatic keratinocytes by activating the TAK1-MK2-HSP27 pathway. | FEBS J | 2026 | 42089462 | PubTator, text mining | PubMed |
| Genetic determinants of fatigue up to 2 years after radiotherapy in prostate cancer patients. | Nat Commun | 2026 | 42020408 | PubTator, text mining | PubMed |
| Arp2/3 Inhibition Suppresses Membrane Dynamics but Does Not Block Pigment Granule Migration in Isolated Fish Retinal Pigment Epithelial (RPE) Cells. | Cytoskeleton (Hoboken) | 2026 | 41834087 | PubTator, text mining | PubMed |
| The Impact of Maternal Diabetes and Hypothyroidism on Signaling Pathway Activation and Gene Expression in Fetal Mesenchymal Stem Cells. | Biomedicines | 2026 | 41751334 | PubTator, text mining | PubMed |
| The Role of Actin-Binding Proteins in Breast Cancer Progression. | Breast Cancer (Dove Med Press) | 2026 | 41743193 | PubTator, text mining | PubMed |
| Acute priming using elevated fluid viscosity recovers 'young-like' single-cell surveillance behaviors in aged human T cells. | bioRxiv | 2026 | 41648320 | PubTator, text mining | PubMed |
1 to 10 of 2,778
See all 2,778 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/10096
GET https://conductscience.org/api/genes/v1/10096/patents?page=2