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Gene · 10096

ACTR3: actin related protein 3

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ACTR3: actin related protein 3. Genes, record 10096. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10096

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Gene

Symbol
ACTR3
HGNC
Name
actin related protein 3
HGNC
NCBI Gene ID
10096
NCBI Gene
HGNC ID
HGNC:170
HGNC
Ensembl
ENSG00000115091
NCBI Gene
Aliases
ARP3
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P61158Actin-related protein 34185Ensembl, GeneID, HGNC

Source UniProt

Patents33

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
WO 2026063308 A2026-03-268P61158Espacenet
EP 4650780 A22025-11-192180P61158Espacenet
JP 2025517970 A2025-06-122180P61158Espacenet
JP 2025062604 A2025-04-146431P61158Espacenet
JP 2024123008 A2024-09-104891P61158Espacenet
US 11446398 B22022-09-206431P61158Espacenet
JP 2022524081 A2022-04-27109402P61158Espacenet
US 10501513 B22019-12-104891P61158Espacenet
US 10190166 B22019-01-2984P61158Espacenet
EP 3403091 A12018-11-21413P61158Espacenet

1 to 10 of 33

See all 33 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,704

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleACTR3 papersNewest fiscal year
R01GM073791Structural-Functional Basis of Actin Cytoskeleton Dynamics202025
P30CA008748Cancer Center Support Grant72025
P30CA016086Cancer Center Support Grant72025
R35GM136319Control of actin filament networks by Arp2/3 complex and its regulators62025
P30CA016672Cancer Center Support Grant52025
P40OD018537Bloomington Drosophila Stock Center at Indiana University52025
R35GM118119Assembly and function of cytoskeletal systems in eukaryotic and prokaryoticcells52025
P01HL126609Cytoskeletal Regulation of Lung Endothelial Pathobiology in ARDS42025
P20GM113132The Institute for Biomolecular Targeting42025
P30CA015704Cancer Center Support Grant42025

1 to 10 of 1,704Source NIH's project files

See all 1,704 nih grants

Papers2,778

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Integrative WGBS and ATAC-seq profiling reveals epigenetic and chromatin accessibility signatures associated with clutch length in goose ovaries.Poult Sci202642727346PubTator, text miningPubMed
Genome-wide association study of egg numbers across different laying phases in a large-scale layer population.Br Poult Sci202642615881PubTator, text miningPubMed
Arp2/3 Inhibition Synergizes With PARP Inhibitors by Impairing Homologous Recombination in Gastric Cancer Cells.Front Biosci (Landmark Ed)202642530272PubTator, text miningPubMed
Inorganic phosphate rapidly switches the stability of Arp2/3-induced actin branches.J Cell Biol202642424095PubTator, text miningPubMed
ACTR3 enhances the hyperproliferation of psoriatic keratinocytes by activating the TAK1-MK2-HSP27 pathway.FEBS J202642089462PubTator, text miningPubMed
Genetic determinants of fatigue up to 2 years after radiotherapy in prostate cancer patients.Nat Commun202642020408PubTator, text miningPubMed
Arp2/3 Inhibition Suppresses Membrane Dynamics but Does Not Block Pigment Granule Migration in Isolated Fish Retinal Pigment Epithelial (RPE) Cells.Cytoskeleton (Hoboken)202641834087PubTator, text miningPubMed
The Impact of Maternal Diabetes and Hypothyroidism on Signaling Pathway Activation and Gene Expression in Fetal Mesenchymal Stem Cells.Biomedicines202641751334PubTator, text miningPubMed
The Role of Actin-Binding Proteins in Breast Cancer Progression.Breast Cancer (Dove Med Press)202641743193PubTator, text miningPubMed
Acute priming using elevated fluid viscosity recovers 'young-like' single-cell surveillance behaviors in aged human T cells.bioRxiv202641648320PubTator, text miningPubMed

1 to 10 of 2,778

See all 2,778 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/10096

GET https://conductscience.org/api/genes/v1/10096/patents?page=2