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Gene · 10097

ACTR2: actin related protein 2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ACTR2: actin related protein 2. Genes, record 10097. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10097

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Gene

Symbol
ACTR2
HGNC
Name
actin related protein 2
HGNC
NCBI Gene ID
10097
NCBI Gene
HGNC ID
HGNC:169
HGNC
Ensembl
ENSG00000138071
NCBI Gene
Aliases
ARP2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P61160Actin-related protein 23945Ensembl, GeneID, HGNC

Source UniProt

Patents28

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-191815P61160Espacenet
EP 4641201 A22025-10-291398P61160Espacenet
JP 2025517969 A2025-06-121398P61160Espacenet
JP 2025517970 A2025-06-121815P61160Espacenet
JP 2025062604 A2025-04-146428P61160Espacenet
JP 2024123008 A2024-09-104887P61160Espacenet
US 11446398 B22022-09-206428P61160Espacenet
JP 2022524081 A2022-04-27109399P61160Espacenet
WO 2020043864 A12020-03-05209P61160Espacenet
US 10501513 B22019-12-104887P61160Espacenet

1 to 10 of 28

See all 28 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,713

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleACTR2 papersNewest fiscal year
R01GM073791Structural-Functional Basis of Actin Cytoskeleton Dynamics192025
P30CA016086Cancer Center Support Grant82025
P30CA016672Cancer Center Support Grant72025
P30CA008748Cancer Center Support Grant62025
R35GM136319Control of actin filament networks by Arp2/3 complex and its regulators62025
P20GM113132The Institute for Biomolecular Targeting52025
R35GM118119Assembly and function of cytoskeletal systems in eukaryotic and prokaryoticcells52025
P30CA023108Cancer Center Support Grant42025
P30EY008126Core Grant in Vision Research42025
R35GM122545The impact of dynamic actin polymerization on mitochondrial dynamics and function42025

1 to 10 of 1,713Source NIH's project files

See all 1,713 nih grants

Papers2,756

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Comparative proteomic and metabolomic profiling of transparent versus opaque pigeon egg albumen.J Sci Food Agric202642706888PubTator, text miningPubMed
Omics Profiling of Patients with Obstructive Sleep Apnoea Reveals Risks of Diabetes Mellitus and Cardiovascular Diseases.J Proteome Res202642695875PubTator, text miningPubMed
Arp2/3 complex-dependent actin remodeling is required for efficient RSV uncoating in A549 cells.J Virol202642671551PubTator, text miningPubMed
METTL3-Mediated m6A Modification of ACTR2 Promotes Trophoblast Cell Growth, Migration and Invasion in Unexplained Recurrent Spontaneous Abortion.Cell Biochem Biophys202642631821PubTator, text miningPubMed
Arp2/3 Inhibition Synergizes With PARP Inhibitors by Impairing Homologous Recombination in Gastric Cancer Cells.Front Biosci (Landmark Ed)202642530272PubTator, text miningPubMed
Inorganic phosphate rapidly switches the stability of Arp2/3-induced actin branches.J Cell Biol202642424095PubTator, text miningPubMed
A human corticospinal organoid-slice connectoid model informs enhancer strategies for post-injury axon regrowth.Cell Rep202642201810PubTator, text miningPubMed
Machine Learning-Based Classification of Gliomas and Tumor Grades with SHAP-Guided Feature Interpretation.Genes (Basel)202642194968PubTator, text miningPubMed
Paxillin mediates ARP2-dependent actin assembly for spindle migration in mammalian oocyte meiosis.Biol Direct202641963992PubTator, text miningPubMed
Differential MicroRNA Expression in Chronic Spontaneous Urticaria in Relation to Treatment Response.Allergy Asthma Immunol Res202641914533PubTator, text miningPubMed

1 to 10 of 2,756

See all 2,756 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/10097

GET https://conductscience.org/api/genes/v1/10097/patents?page=2