Gene · 10097
ACTR2: actin related protein 2
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. ACTR2: actin related protein 2. Genes, record 10097. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10097
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P61160 | Actin-related protein 2 | 394 | 5 | Ensembl, GeneID, HGNC |
Source UniProt
Patents28
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4650780 A2 | 2025-11-19 | 1815 | P61160 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 1398 | P61160 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 1398 | P61160 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 1815 | P61160 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 6428 | P61160 | Espacenet |
| JP 2024123008 A | 2024-09-10 | 4887 | P61160 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 6428 | P61160 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 109399 | P61160 | Espacenet |
| WO 2020043864 A1 | 2020-03-05 | 209 | P61160 | Espacenet |
| US 10501513 B2 | 2019-12-10 | 4887 | P61160 | Espacenet |
1 to 10 of 28
See all 28 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,713
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | ACTR2 papers | Newest fiscal year |
|---|---|---|---|
| R01GM073791 | Structural-Functional Basis of Actin Cytoskeleton Dynamics | 19 | 2025 |
| P30CA016086 | Cancer Center Support Grant | 8 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 7 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 6 | 2025 |
| R35GM136319 | Control of actin filament networks by Arp2/3 complex and its regulators | 6 | 2025 |
| P20GM113132 | The Institute for Biomolecular Targeting | 5 | 2025 |
| R35GM118119 | Assembly and function of cytoskeletal systems in eukaryotic and prokaryoticcells | 5 | 2025 |
| P30CA023108 | Cancer Center Support Grant | 4 | 2025 |
| P30EY008126 | Core Grant in Vision Research | 4 | 2025 |
| R35GM122545 | The impact of dynamic actin polymerization on mitochondrial dynamics and function | 4 | 2025 |
1 to 10 of 1,713Source NIH's project files
See all 1,713 nih grantsPapers2,756
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Comparative proteomic and metabolomic profiling of transparent versus opaque pigeon egg albumen. | J Sci Food Agric | 2026 | 42706888 | PubTator, text mining | PubMed |
| Omics Profiling of Patients with Obstructive Sleep Apnoea Reveals Risks of Diabetes Mellitus and Cardiovascular Diseases. | J Proteome Res | 2026 | 42695875 | PubTator, text mining | PubMed |
| Arp2/3 complex-dependent actin remodeling is required for efficient RSV uncoating in A549 cells. | J Virol | 2026 | 42671551 | PubTator, text mining | PubMed |
| METTL3-Mediated m6A Modification of ACTR2 Promotes Trophoblast Cell Growth, Migration and Invasion in Unexplained Recurrent Spontaneous Abortion. | Cell Biochem Biophys | 2026 | 42631821 | PubTator, text mining | PubMed |
| Arp2/3 Inhibition Synergizes With PARP Inhibitors by Impairing Homologous Recombination in Gastric Cancer Cells. | Front Biosci (Landmark Ed) | 2026 | 42530272 | PubTator, text mining | PubMed |
| Inorganic phosphate rapidly switches the stability of Arp2/3-induced actin branches. | J Cell Biol | 2026 | 42424095 | PubTator, text mining | PubMed |
| A human corticospinal organoid-slice connectoid model informs enhancer strategies for post-injury axon regrowth. | Cell Rep | 2026 | 42201810 | PubTator, text mining | PubMed |
| Machine Learning-Based Classification of Gliomas and Tumor Grades with SHAP-Guided Feature Interpretation. | Genes (Basel) | 2026 | 42194968 | PubTator, text mining | PubMed |
| Paxillin mediates ARP2-dependent actin assembly for spindle migration in mammalian oocyte meiosis. | Biol Direct | 2026 | 41963992 | PubTator, text mining | PubMed |
| Differential MicroRNA Expression in Chronic Spontaneous Urticaria in Relation to Treatment Response. | Allergy Asthma Immunol Res | 2026 | 41914533 | PubTator, text mining | PubMed |
1 to 10 of 2,756
See all 2,756 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/10097
GET https://conductscience.org/api/genes/v1/10097/patents?page=2