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RAD50: RAD50 double strand break repair protein

1 protein, 51 patents, 0 drugs, 0 trials, 4,232 NIH grants and 7,083 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolRAD50HGNC
NameRAD50 double strand break repair proteinHGNC
NCBI Gene ID10111NCBI Gene
HGNC IDHGNC:9816HGNC
EnsemblENSG00000113522NCBI Gene
AliasesNBSLD, RAD50-2, RAD502, hRad50NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q92878DNA repair protein RAD501,3126Ensembl, GeneID, HGNCUniProt

Patents 51

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-1910092Q92878Espacenet
EP 4641201 A22025-10-2910384Q92878Espacenet
JP 2025100656 A2025-07-036Q92878Espacenet
JP 2025517969 A2025-06-1210384Q92878Espacenet
JP 2025517970 A2025-06-1210092Q92878Espacenet
EP 4464338 A22024-11-20153Q92878Espacenet
JP 2024123008 A2024-09-108011Q92878Espacenet
US 11976334 B22024-05-07192Q92878Espacenet
US 11680268 B22023-06-20153Q92878Espacenet
US 11446398 B22022-09-2071067Q92878Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 4232

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant952,025NIH's project files
P01CA092584Structural Cell Biology of DNA Repair Machines902,025NIH's project files
P30CA016672Cancer Center Support Grant812,025NIH's project files
ZIABC006150DNA Repair, Cell Cycle Checkpoints and Apoptosis as Targets for Anticancer Drugs212,025NIH's project files
P30CA016086Cancer Center Support Grant162,025NIH's project files
P30CA006927Comprehensive Cancer Center Program at Fox Chase152,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)142,025NIH's project files
P50CA116201Mayo Clinic Breast Cancer SPORE142,025NIH's project files
P30CA016058Cancer Center Support Grant132,025NIH's project files
ZIAAG000741Roles Of DNA Helicases In Pathways Required For Maintenance Of Genomic Stability132,025NIH's project files

Papers 7083

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42738331PubTator, text miningPubMed
42693354PubTator, text miningPubMed
42673958PubTator, text miningPubMed
42594331PubTator, text miningPubMed
42535577PubTator, text miningPubMed
42516375PubTator, text miningPubMed
42498519PubTator, text miningPubMed
42487270PubTator, text miningPubMed
42484294PubTator, text miningPubMed
42449748PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license