Gene · 10114
HIPK3: homeodomain interacting protein kinase 3
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. HIPK3: homeodomain interacting protein kinase 3. Genes, record 10114. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10114
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q9H422 | Homeodomain-interacting protein kinase 3 | 1,215 | 2 | Ensembl, GeneID, HGNC |
Source UniProt
Patents13
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 49347 | Q9H422 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 4256 | Q9H422 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 3818 | Q9H422 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 1955 | Q9H422 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 1955 | Q9H422 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 3818 | Q9H422 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 4256 | Q9H422 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 38887 | Q9H422 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 141858 | Q9H422 | Espacenet |
| JP 2019054813 A | 2019-04-11 | 229782 | Q9H422 | Espacenet |
1 to 10 of 13
See all 13 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants441
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | HIPK3 papers | Newest fiscal year |
|---|---|---|---|
| ZIAAG000511 | Post-transcriptional control of Proliferation, Stress Response & Carcinogenesis | 4 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 3 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 2 | 2025 |
| P30CA142543 | UT Southwestern Medical Center Simmons Comprehensive Cancer Center | 2 | 2025 |
| P50CA196530 | Yale SPORE in Lung Cancer (YSILC): The Biology and Personalized Treatment of Lung Cancer | 2 | 2025 |
| R01AI127375 | Systematic Analysis of Morphogenesis, Commensalism, and Virulence in a Leading Human Fungal Pathogen | 2 | 2025 |
| R01HL089221 | Determinants of AAV Tropism | 2 | 2025 |
| R35GM119735 | Regulatory roles for the Integrator complex and circular RNAs | 2 | 2025 |
| I01BX000332 | Posttranscriptional Control of Gut Mucosal Defense and Homeostasis | 1 | 2025 |
| IK6BX004213 | BLRD Research Career Scientist Award Application | 1 | 2025 |
1 to 10 of 441Source NIH's project files
See all 441 nih grantsPapers1,341
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| CircHIPK3 promotes the progression of B-cell acute lymphoblastic leukemia in children by binding to STAT3. | Front Pharmacol | 2026 | 42824327 | PubTator, text mining | PubMed |
| PBMC circRNA Profiles Distinguish Atypical From Idiopathic Parkinsonism and Track Clinical Severity Across Syndromes. | J Neurochem | 2026 | 42415371 | PubTator, text mining | PubMed |
| HIPK3 silencing promotes M2 macrophage polarization through NF-κB signaling pathway to enhance oral cancer progression. | Mol Genet Genomics | 2026 | 42371219 | PubTator, text mining | PubMed |
| Research progress of plant-derived chemical compounds for overcoming pancreatic cancer drug resistance. | World J Gastroenterol | 2026 | 41810441 | PubTator, text mining | PubMed |
| Circular RNAs: Key Regulators of Tumor Metabolic Reprogramming and Clinical Translation. | Oncol Res | 2026 | 41799520 | PubTator, text mining | PubMed |
| Divergent roles of circMPP6 and its parental gene MPP6 in non-small cell lung cancer. | Front Cell Dev Biol | 2026 | 41799439 | PubTator, text mining | PubMed |
| Blood-based epigenetic biomarkers in rheumatoid arthritis: current knowledge and future perspectives. | Front Immunol | 2026 | 41798917 | PubTator, text mining | PubMed |
| TUBB2A and TM4SF1 Methylation Define Prognostic Subgroups in Adult-Type Diffuse Glioma. | Cancers (Basel) | 2026 | 41749891 | PubTator, text mining | PubMed |
| Chinese Herbal Medicines for Diabetic Cardio-Cerebrovascular Diseases: Key Bioactive Metabolites and Action Mechanisms. | J Nutr Metab | 2026 | 41743998 | PubTator, text mining | PubMed |
| Comparison of CRISPR Sequences in Archaea and Bacteria with Eukaryotic microRNAs. | Avicenna J Med Biotechnol | 2025 | 41727334 | PubTator, text mining | PubMed |
1 to 10 of 1,341
See all 1,341 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/10114
GET https://conductscience.org/api/genes/v1/10114/patents