Gene · 10131
TRAP1: TNF receptor associated protein 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. TRAP1: TNF receptor associated protein 1. Genes, record 10131. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10131
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q12931 | Heat shock protein 75 kDa, mitochondrial | 704 | 24 | Ensembl, GeneID, HGNC |
Source UniProt
Patents60
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 67195 | Q12931 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 1210 | Q12931 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 859 | Q12931 | Espacenet |
| EP 4641202 A2 | 2025-10-29 | 4431 | Q12931 | Espacenet |
| EP 4582098 A2 | 2025-07-09 | 1369 | Q12931 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 859 | Q12931 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 1210 | Q12931 | Espacenet |
| KR 1020250017231 A | 2025-02-04 | 4431 | Q12931 | Espacenet |
| JP 2024112982 A | 2024-08-21 | 4513 | Q12931 | Espacenet |
| US 11694765 B2 | 2023-07-04 | 154 | Q12931 | Espacenet |
1 to 10 of 60
See all 60 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,180
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | TRAP1 papers | Newest fiscal year |
|---|---|---|---|
| P30CA010815 | Consolidated Basic Cancer Research Program | 17 | 2025 |
| ZIASC010074 | HSP90 and HSP70 Chaperone Proteins and Interactors in Cellular Signal Transduction | 14 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 13 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 6 | 2025 |
| ZIABC011032 | Post-translational modifications of Hsp90 | 6 | 2025 |
| R50CA211199 | Integrative Approach to Comprehensive Analysis of High Throughput Data on a Cancer Center Level | 4 | 2025 |
| P30CA013696 | Cancer Center Support Grant | 3 | 2025 |
| P30CA014051 | Cancer Center Support (Core) Grant | 3 | 2025 |
| R01EY021205 | Characterization of purified myocilin: glaucoma as a protein misfolding disease | 3 | 2025 |
| R35GM139584 | Regulatory mechanisms of the Hsp90 chaperone machinery | 3 | 2025 |
1 to 10 of 1,180Source NIH's project files
See all 1,180 nih grantsPapers1,889
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Coordinated regulation of the metaboproteome by Hsp90 chaperones controls metabolic plasticity. | iScience | 2026 | 42761197 | PubTator, text mining | PubMed |
| A poly-L-lysine-functionalized electrochemical immunosensor enables highly sensitive detection of tumor necrosis factor receptor-associated protein 1. | Turk J Chem | 2026 | 42683372 | PubTator, text mining | PubMed |
| The pro-tumorigenic functions of cancer-associated adipocytes are dependent on the mitochondrial chaperone tumor necrosis factor receptor-associated protein 1. | Signal Transduct Target Ther | 2026 | 42509229 | PubTator, text mining | PubMed |
| Isoform-selective HSP90 inhibition as a precision therapeutic strategy for neurodegenerative and metabolic diseases. | Prog Neuropsychopharmacol Biol Psychiatry | 2026 | 42508631 | PubTator, text mining | PubMed |
| HSP90 inhibition partially rescues alternative splicing dysregulation in cell models of myotonic dystrophy. | J Biol Chem | 2026 | 42486259 | PubTator, text mining | PubMed |
| Target deconvolution of a selective HepG2 cytotoxic hit identifies GSTP1 and TRAP1 as candidate molecular targets. | RSC Adv | 2026 | 42433452 | PubTator, text mining | PubMed |
| Plasma proteomics analysis of vitamin C supplementation in people with type 2 diabetes. | Nutr Diabetes | 2026 | 42373594 | PubTator, text mining | PubMed |
| TRAP1 ablation improves mitochondrial cristae and oxidative phosphorylation in pancreatic cancer stem cells. | Cancer Drug Resist | 2026 | 42267195 | PubTator, text mining | PubMed |
| Retraction Note: Knockdown of TRAP1 promotes cisplatin-induced apoptosis by promoting the ROS-dependent mitochondrial dysfunction in lung cancer cells. | Mol Cell Biochem | 2026 | 42234383 | PubTator, text mining | PubMed |
| Prognostic model construction and drug prediction in colorectal cancer using mitochondrial programmed cell death-related genes. | Clin Transl Oncol | 2026 | 42184077 | PubTator, text mining | PubMed |
1 to 10 of 1,889
See all 1,889 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/10131
GET https://conductscience.org/api/genes/v1/10131/patents?page=2