Gene · 10146
G3BP1: G3BP stress granule assembly factor 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. G3BP1: G3BP stress granule assembly factor 1. Genes, record 10146. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10146
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q13283 | Ras GTPase-activating protein-binding protein 1 | 466 | 20 | Ensembl, GeneID, HGNC |
Source UniProt
Patents56
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 48390 | Q13283 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 48391 | Q13283 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 7267 | Q13283 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 7212 | Q13283 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 7212 | Q13283 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 7267 | Q13283 | Espacenet |
| US 12195768 B2 | 2025-01-14 | 3 | Q13283 | Espacenet |
| US 11892452 B2 | 2024-02-06 | 116 | Q13283 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 36649 | Q13283 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 36650 | Q13283 | Espacenet |
1 to 10 of 56
See all 56 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,989
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | G3BP1 papers | Newest fiscal year |
|---|---|---|---|
| P30CA125123 | Baylor College of Medicine Cancer Center - Cancer Center Support Grant | 12 | 2025 |
| P30CA021765 | Cancer Center Support Grant (CCSG) | 9 | 2025 |
| P30DK056338 | Texas Medical Center Digestive Diseases Center | 8 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 7 | 2025 |
| P30CA016086 | Cancer Center Support Grant | 6 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 5 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 5 | 2025 |
| P20GM121176 | Autophagy, Inflammation and Metabolism (AIM) in Disease Center - Phase 2. | 4 | 2025 |
| P30CA016087 | Cancer Center Support Grant | 4 | 2025 |
| P30CA022453 | CANCER CENTER SUPPORT GRANT | 4 | 2025 |
1 to 10 of 1,989Source NIH's project files
See all 1,989 nih grantsPapers3,155
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Biomimetic stress granules replenish lysosomal repair to reinstate macrophage immunometabolic antibacterial programs. | Bioact Mater | 2027 | 42598102 | PubTator, text mining | PubMed |
| Cryopreservation Disrupts TRIM21-Mediated AKAP3 Ubiquitination and Triggers Stress Granule Formation in Human Sperm. | Andrology | 2026 | 42816460 | PubTator, text mining | PubMed |
| Stress granule phase transitions and neuronal fate in cerebral ischemia-reperfusion injury. | Front Mol Neurosci | 2026 | 42769600 | PubTator, text mining | PubMed |
| Gadd45β is critical for regulation of type I interferon signaling by facilitating G3BP-mediated stress granule formation. | Cell Rep | 2026 | 42731031 | PubTator, text mining | PubMed |
| Development of m6A-related prognostic models for survival in lung squamous cell carcinoma with different PD-L1 expression levels. | Transl Cancer Res | 2026 | 42724890 | PubTator, text mining | PubMed |
| Directed evolution of Lantern enables rapid RNA and protein proximity labeling. | Nat Chem Biol | 2026 | 42706326 | PubTator, text mining | PubMed |
| Brucea javanica Oil Emulsion Promotes Breast Cancer Cell Autophagy and Apoptosis by Regulating PAX6 mRNA Stability Through the hsa_circ_0001589/G3BP1 Axis. | Clin Exp Pharmacol Physiol | 2026 | 42661539 | PubTator, text mining | PubMed |
| Negative Pressure Promotes G3BP1-Mediated Migration of Corneal Epithelial Cells Through Activation of AKT/ERK/Paxillin Pathway. | Int J Mol Sci | 2026 | 42653280 | PubTator, text mining | PubMed |
| G3BP1 depletion, observed in Parkinson's Disease, drives Golgi-lysosome-autophagy defects. | Cell Death Differ | 2026 | 42642486 | PubTator, text mining | PubMed |
| Zinc increases stress granule formation by promoting RNA condensation. | Cell Rep | 2026 | 42636110 | PubTator, text mining | PubMed |
1 to 10 of 3,155
See all 3,155 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/10146
GET https://conductscience.org/api/genes/v1/10146/patents?page=2