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Gene · 10146

G3BP1: G3BP stress granule assembly factor 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. G3BP1: G3BP stress granule assembly factor 1. Genes, record 10146. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10146

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Gene

Symbol
G3BP1
HGNC
Name
G3BP stress granule assembly factor 1
HGNC
NCBI Gene ID
10146
NCBI Gene
HGNC ID
HGNC:30292
HGNC
Ensembl
ENSG00000145907
NCBI Gene
Aliases
G3BP, HDH-VIII
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q13283Ras GTPase-activating protein-binding protein 146620Ensembl, GeneID, HGNC

Source UniProt

Patents56

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1448390Q13283Espacenet
JP 2026004568 A2026-01-1448391Q13283Espacenet
EP 4650780 A22025-11-197267Q13283Espacenet
EP 4641201 A22025-10-297212Q13283Espacenet
JP 2025517969 A2025-06-127212Q13283Espacenet
JP 2025517970 A2025-06-127267Q13283Espacenet
US 12195768 B22025-01-143Q13283Espacenet
US 11892452 B22024-02-06116Q13283Espacenet
US 11446398 B22022-09-2036649Q13283Espacenet
US 11446398 B22022-09-2036650Q13283Espacenet

1 to 10 of 56

See all 56 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,989

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleG3BP1 papersNewest fiscal year
P30CA125123Baylor College of Medicine Cancer Center - Cancer Center Support Grant122025
P30CA021765Cancer Center Support Grant (CCSG)92025
P30DK056338Texas Medical Center Digestive Diseases Center82025
P30CA008748Cancer Center Support Grant72025
P30CA016086Cancer Center Support Grant62025
P30CA016672Cancer Center Support Grant52025
P30CA068485Cancer Center Support Grant52025
P20GM121176Autophagy, Inflammation and Metabolism (AIM) in Disease Center - Phase 2.42025
P30CA016087Cancer Center Support Grant42025
P30CA022453CANCER CENTER SUPPORT GRANT42025

1 to 10 of 1,989Source NIH's project files

See all 1,989 nih grants

Papers3,155

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Biomimetic stress granules replenish lysosomal repair to reinstate macrophage immunometabolic antibacterial programs.Bioact Mater202742598102PubTator, text miningPubMed
Cryopreservation Disrupts TRIM21-Mediated AKAP3 Ubiquitination and Triggers Stress Granule Formation in Human Sperm.Andrology202642816460PubTator, text miningPubMed
Stress granule phase transitions and neuronal fate in cerebral ischemia-reperfusion injury.Front Mol Neurosci202642769600PubTator, text miningPubMed
Gadd45β is critical for regulation of type I interferon signaling by facilitating G3BP-mediated stress granule formation.Cell Rep202642731031PubTator, text miningPubMed
Development of m6A-related prognostic models for survival in lung squamous cell carcinoma with different PD-L1 expression levels.Transl Cancer Res202642724890PubTator, text miningPubMed
Directed evolution of Lantern enables rapid RNA and protein proximity labeling.Nat Chem Biol202642706326PubTator, text miningPubMed
Brucea javanica Oil Emulsion Promotes Breast Cancer Cell Autophagy and Apoptosis by Regulating PAX6 mRNA Stability Through the hsa_circ_0001589/G3BP1 Axis.Clin Exp Pharmacol Physiol202642661539PubTator, text miningPubMed
Negative Pressure Promotes G3BP1-Mediated Migration of Corneal Epithelial Cells Through Activation of AKT/ERK/Paxillin Pathway.Int J Mol Sci202642653280PubTator, text miningPubMed
G3BP1 depletion, observed in Parkinson's Disease, drives Golgi-lysosome-autophagy defects.Cell Death Differ202642642486PubTator, text miningPubMed
Zinc increases stress granule formation by promoting RNA condensation.Cell Rep202642636110PubTator, text miningPubMed

1 to 10 of 3,155

See all 3,155 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/10146

GET https://conductscience.org/api/genes/v1/10146/patents?page=2