Gene · 10148
EBI3: Epstein-Barr virus induced 3
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. EBI3: Epstein-Barr virus induced 3. Genes, record 10148. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10148
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q14213 | Interleukin-27 subunit beta | 229 | 4 | Ensembl, GeneID, HGNC |
Source UniProt
Patents162
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| WO 2026171886 A1 | 2026-08-20 | 8 | Q14213 | Espacenet |
| EP 4791437 A1 | 2026-08-19 | 175 | Q14213 | Espacenet |
| EP 4757832 A1 | 2026-06-17 | 444 | Q14213 | Espacenet |
| JP 2026016604 A | 2026-02-03 | 698 | Q14213 | Espacenet |
| US 12534732 B2 | 2026-01-27 | 917 | Q14213 | Espacenet |
| JP 2026012378 A | 2026-01-23 | 917 | Q14213 | Espacenet |
| JP 2026502391 A | 2026-01-22 | 1 | Q14213 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 45165 | Q14213 | Espacenet |
| US 12516329 B2 | 2026-01-06 | 917 | Q14213 | Espacenet |
| EP 4670792 A2 | 2025-12-31 | 917 | Q14213 | Espacenet |
1 to 10 of 162
See all 162 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,060
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | EBI3 papers | Newest fiscal year |
|---|---|---|---|
| P30CA021765 | Cancer Center Support Grant (CCSG) | 13 | 2025 |
| P30CA016086 | Cancer Center Support Grant | 8 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 7 | 2025 |
| R37CA230786 | Function of IL35+ B cells in pancreatic cancer | 6 | 2025 |
| ZIAEY000262 | Role of IL-12 family cytokines in autoimmune Uveitis | 6 | 2025 |
| ZIAEY000350 | Development of Immunologic therapies against uveitis | 6 | 2025 |
| ZIAEY000372 | Mechanisms of immune homeostasis and regulation of intraocular inflammation | 6 | 2025 |
| P30CA047904 | Cancer Center Support Grant | 5 | 2025 |
| P30CA014520 | UW Comprehensive Cancer Center Support | 4 | 2025 |
| R01AI051321 | Structure-based engineering of immune cytokine signaling | 4 | 2025 |
1 to 10 of 1,060Source NIH's project files
See all 1,060 nih grantsPapers1,901
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Discordant Interleukin-27 (IL-27) Subunit Transcription in Human Sepsis Exposes a Molecular-Attribution Gap. | Biomedicines | 2026 | 42792776 | PubTator, text mining | PubMed |
| Molecular Heterogeneity in Clinically Ambiguous Atopic Dermatitis-Psoriasis Overlap: Compartment-Resolved Transcriptomic Profiling. | Allergy | 2026 | 42788674 | PubTator, text mining | PubMed |
| Candidate proteomic indirect-effect signals linking dementia to probable muscle-bone fragility: a UK Biobank cohort study. | Front Med (Lausanne) | 2026 | 42780496 | PubTator, text mining | PubMed |
| Shifting the paradigm in bipolar disorder: moving beyond conventional inflammatory markers to novel EBI3-containing heterodimeric cytokines. | Front Psychiatry | 2026 | 42712571 | PubTator, text mining | PubMed |
| Immunomodulatory effects of palm-derived tocotrienol-rich fraction in healthy volunteers following influenza vaccination: A randomised clinical trial. | Nutr Res | 2026 | 42579941 | PubTator, text mining | PubMed |
| Free Epstein-Barr virus-induced gene 3 functions as an autonomous immunosuppressive cytokine to maintain immune tolerance. | Front Immunol | 2026 | 42577052 | PubTator, text mining | PubMed |
| Elevated cytokine and nitric oxide levels in Behçet disease: EBI-3 as a potential biomarker of vascular involvement. | Immunol Lett | 2026 | 42144143 | PubTator, text mining | PubMed |
| Metastatic adenocarcinomas of left colon and rectum: differences in clinical outcome and gene expression. | Front Oncol | 2026 | 42063709 | PubTator, text mining | PubMed |
| Interleukin 12β and EBI3: Emerging immunomodulatory members of the interleukin 12 family. | Biochim Biophys Acta Mol Cell Res | 2026 | 41956257 | PubTator, text mining | PubMed |
| Glucocorticoid signaling regulates expression of the EBI3 subunit of IL-27 in neonatal macrophages: Implications for antenatal corticosteroid therapy. | bioRxiv | 2026 | 41929190 | PubTator, text mining | PubMed |
1 to 10 of 1,901
See all 1,901 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/10148
GET https://conductscience.org/api/genes/v1/10148/patents?page=2