Gene · 10159
ATP6AP2: ATPase H+ transporting accessory protein 2
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. ATP6AP2: ATPase H+ transporting accessory protein 2. Genes, record 10159. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10159
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| O75787 | Renin receptor | 350 | 10 | Ensembl, GeneID, HGNC |
Source UniProt
Patents53
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 38290 | O75787 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 19125 | O75787 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 24065 | O75787 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 1251 | O75787 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 524 | O75787 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 5548 | O75787 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 524 | O75787 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 5548 | O75787 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 24065 | O75787 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 19125 | O75787 | Espacenet |
1 to 10 of 53
See all 53 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,622
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | ATP6AP2 papers | Newest fiscal year |
|---|---|---|---|
| R01DK104072 | Cloning and characterization of PRR24 as a specific renin receptor critically involved in vasopressin signaling in the kidney | 22 | 2025 |
| P30DK034854 | Integrated Epithelial and Muscosal Biology | 11 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 10 | 2025 |
| P30DK034989 | Yale Liver Center | 10 | 2025 |
| R01DK099097 | Functional outcomes of inflammatory bowel disease associated variants | 10 | 2025 |
| U54GM104940 | Louisiana Clinical and Translational Science Center | 8 | 2025 |
| R01DK067299 | Novel Roles and Mechanisms of Proximal Tubule Mitochondrial Angiotensin II and Sirtuin 3 in Hypertension | 7 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 7 | 2025 |
| R01AI137168 | Characterizing the Mechanism of DPP8/9 Inhibitor-Induced Pyroptosis | 6 | 2025 |
| U01DK062422 | Mount Sinai NYC Genetics Research Center: Multi-omic integration across data-types, cell niches and populations | 6 | 2025 |
1 to 10 of 1,622Source NIH's project files
See all 1,622 nih grantsPapers2,607
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Mechanistic Assessment of Norepinephrine Therapy versus Angiotensin-II in Septic Shock (MANTRA): Study Protocol for a multicenter randomized trial. | medRxiv | 2026 | 42779856 | PubTator, text mining | PubMed |
| Pediatric Non-Neural Granular Cell Tumor With Unexpected Molecular Identity: A Case That Challenges Classification. | Pediatr Dermatol | 2026 | 42680710 | PubTator, text mining | PubMed |
| (Pro)renin Receptor Regulates LDL-C Metabolism and Exacerbates Atherosclerosis via SREBP2/PCSK9/LDLR Pathway. | Korean Circ J | 2026 | 42669859 | PubTator, text mining | PubMed |
| Indoxyl Sulfate and Soluble Prorenin Receptor Axis Contributes to Sarcopenia in Maintenance Hemodialysis Patients by Inducing Mitochondrial Damage: An Integrated Clinical and Experimental Study. | J Ren Nutr | 2026 | 42628817 | PubTator, text mining | PubMed |
| 2024 Donald Seldin Lecture: New Insights Into Soluble (Pro)Renin Receptor in Hypertension and Kidney Disease. | Hypertension | 2026 | 42605676 | PubTator, text mining | PubMed |
| Association between adipose (pro)renin receptor expression and growth hormone deficiency in patients with non-functioning hypothalamic-pituitary masses. | J Endocrinol Invest | 2026 | 42461577 | PubTator, text mining | PubMed |
| Platelet RIP2 Limits Dense Granule Release and Thrombosis via DOCK8-Cdc42. | Arterioscler Thromb Vasc Biol | 2026 | 42273729 | PubTator, text mining | PubMed |
| Characterization of elevated levels of endometrial renin-angiotensin system components suggest a role in endometrial repair. | Front Endocrinol (Lausanne) | 2026 | 42130729 | PubTator, text mining | PubMed |
| Granular Cell Dermatofibroma Demonstrates Loss-of-Function Mutations in V-ATPase Component Genes. | J Cutan Pathol | 2026 | 42108978 | PubTator, text mining | PubMed |
| Spectrum and functions of ion channels and transporters in osteoclasts. | Bone Res | 2026 | 41896521 | PubTator, text mining | PubMed |
1 to 10 of 2,607
See all 2,607 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/10159
GET https://conductscience.org/api/genes/v1/10159/patents?page=2