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LPCAT3: lysophosphatidylcholine acyltransferase 3
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Gene · 10162

Papers1,424

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

1 to 20 of 1,424

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TitleJournalYearPMIDFound bySource
Pharmacological targeting of ferroptosis in cancer: mechanisms, tumor immunity, and translational challenges.Pharmacol Rep202642789241PubTator, text miningPubMed
Biochanin A promotes KLF6 stabilization to induce ferroptosis and suppress colorectal cancer progression.Cell Signal202642754129PubTator, text miningPubMed
IL1B-high macrophages promote ferroptosis-like lipid peroxidation injury in Crohn's disease intestinal epithelium.Redox Biol202642748656PubTator, text miningPubMed
Ginsenoside Rb1 alleviates AS co-depression disease by targeting the LPCAT3 and modulating the ACSL4/LPCAT3/ALOX15 ferroptosis pathway.Phytomedicine202642710215PubTator, text miningPubMed
DNA methylation-mediated silencing of MALAT1 promotes dexamethasone-induced growth plate chondrocyte ferroptosis via miR-124-3p/LPCAT3.J Bioenerg Biomembr202642709252PubTator, text miningPubMed
LPCAT3 is essential for leukemia progression and represents a therapeutic vulnerability in AML.Blood Sci202642699430PubTator, text miningPubMed
Ferroptosis in Ischemic Stroke: Insights from Natural Product Treatment and Future Directions.Drug Des Devel Ther202642666732PubTator, text miningPubMed
Dual Roles of Natural Products in Regulating Ferroptosis in Acute and Chronic Liver Diseases: A Review.Oxid Med Cell Longev202642610514PubTator, text miningPubMed
Rhubarb extract attenuates periodontitis by modulating an MMP3-associated inflammatory-ferroptotic axis: Integrated multi-omics analysis and experimental validation.Phytomedicine202642501548PubTator, text miningPubMed
NSD2 is a critical regulator of Erastin-induced ferroptosis in keratinocytes.Free Radic Biol Med202642462913PubTator, text miningPubMed
Rethinking LPCAT3 roles in human disease: broadening perspectives beyond ferroptosis.Cell Death Dis202642399667PubTator, text miningPubMed
Lipid droplet associated protein HILPDA promotes hypoxia-induced ferroptosis by driving LPCAT3-mediated polyunsaturated phospholipids enrichment.PLoS One202642258477PubTator, text miningPubMed
ACSL4-driven ferroptosis susceptibility as a targetable vulnerability in monocytic acute myeloid leukemia.Front Oncol202642255227PubTator, text miningPubMed
Gut microbiota-derived short-chain fatty acids attenuate placental ferroptosis and insulin resistance in gestational diabetes via the ACSL4/LPCAT3 pathway.Front Microbiol202642245515PubTator, text miningPubMed
MiR-940 Suppresses Ferroptosis by Controlling Expression of Key Regulatory Genes.Adv Sci (Weinh)202642212965PubTator, text miningPubMed
LF3 exerts anti-osteosarcoma effects through Wnt signaling inhibition-coupled ferroptosis induction via HO-1/ACSL4 axis.Front Oncol202642205761PubTator, text miningPubMed
Explainable machine learning-driven identification of heart failure biomarkers: a multi-model feature selection approach with SHAP-based interpretability.Sci Rep202642185599PubTator, text miningPubMed
Iron chelation targets lipid metabolism to reduce white matter injury in germinal matrix hemorrhage.Cell Death Dis202642177168PubTator, text miningPubMed
SMPD1 modulates malignant progress of osteosarcoma through ferroptosis pathway.Tissue Cell202642139899PubTator, text miningPubMed
Novel aflatoxin oxidase CotA alleviates aflatoxin B1 toxicity in broilers by reducing hepatic AFB1 residues and inhibiting oxidative stress-mediated ferroptosis.Poult Sci202642134142PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

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Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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