Gene · 10162
LPCAT3: lysophosphatidylcholine acyltransferase 3
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. LPCAT3: lysophosphatidylcholine acyltransferase 3. Genes, record 10162. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10162
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q6P1A2 | Lysophospholipid acyltransferase 5 | 487 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents27
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 52144 | Q6P1A2 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 1885 | Q6P1A2 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 1473 | Q6P1A2 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 2412 | Q6P1A2 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 2412 | Q6P1A2 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 1473 | Q6P1A2 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 1885 | Q6P1A2 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 47881 | Q6P1A2 | Espacenet |
| US 11400116 B2 | 2022-08-02 | 3362 | Q6P1A2 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 150852 | Q6P1A2 | Espacenet |
1 to 10 of 27
See all 27 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants654
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | LPCAT3 papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 8 | 2025 |
| R01NS076511 | Lipid Imaging in Traumatic Brain Injury by High Resolution GCIB-secondary Ion Mass Spectrometry | 8 | 2025 |
| P30DK063491 | Diabetes Research Center (DRC) | 6 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 5 | 2025 |
| R01GM122923 | Characterizing the Regulation of Ferroptosis | 4 | 2025 |
| P30DK020572 | Michigan Diabetes Research Center (MDRC) | 3 | 2025 |
| P30DK020579 | Diabetes Research Center | 3 | 2025 |
| P30DK056341 | Washington University Nutrition Obesity Research Center | 3 | 2025 |
| R01CA204232 | Ferroptosis, Cellular Metabolism, and Cancer | 3 | 2025 |
| R01CA247992 | Targeting ferroptosis in radioresistance in lung cancer: mechanisms and preclinical translation | 3 | 2025 |
1 to 10 of 654Source NIH's project files
See all 654 nih grantsPapers1,424
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Pharmacological targeting of ferroptosis in cancer: mechanisms, tumor immunity, and translational challenges. | Pharmacol Rep | 2026 | 42789241 | PubTator, text mining | PubMed |
| Biochanin A promotes KLF6 stabilization to induce ferroptosis and suppress colorectal cancer progression. | Cell Signal | 2026 | 42754129 | PubTator, text mining | PubMed |
| IL1B-high macrophages promote ferroptosis-like lipid peroxidation injury in Crohn's disease intestinal epithelium. | Redox Biol | 2026 | 42748656 | PubTator, text mining | PubMed |
| Ginsenoside Rb1 alleviates AS co-depression disease by targeting the LPCAT3 and modulating the ACSL4/LPCAT3/ALOX15 ferroptosis pathway. | Phytomedicine | 2026 | 42710215 | PubTator, text mining | PubMed |
| DNA methylation-mediated silencing of MALAT1 promotes dexamethasone-induced growth plate chondrocyte ferroptosis via miR-124-3p/LPCAT3. | J Bioenerg Biomembr | 2026 | 42709252 | PubTator, text mining | PubMed |
| LPCAT3 is essential for leukemia progression and represents a therapeutic vulnerability in AML. | Blood Sci | 2026 | 42699430 | PubTator, text mining | PubMed |
| Ferroptosis in Ischemic Stroke: Insights from Natural Product Treatment and Future Directions. | Drug Des Devel Ther | 2026 | 42666732 | PubTator, text mining | PubMed |
| Dual Roles of Natural Products in Regulating Ferroptosis in Acute and Chronic Liver Diseases: A Review. | Oxid Med Cell Longev | 2026 | 42610514 | PubTator, text mining | PubMed |
| Rhubarb extract attenuates periodontitis by modulating an MMP3-associated inflammatory-ferroptotic axis: Integrated multi-omics analysis and experimental validation. | Phytomedicine | 2026 | 42501548 | PubTator, text mining | PubMed |
| NSD2 is a critical regulator of Erastin-induced ferroptosis in keratinocytes. | Free Radic Biol Med | 2026 | 42462913 | PubTator, text mining | PubMed |
1 to 10 of 1,424
See all 1,424 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/10162
GET https://conductscience.org/api/genes/v1/10162/patents?page=2