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Gene · 10162

LPCAT3: lysophosphatidylcholine acyltransferase 3

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. LPCAT3: lysophosphatidylcholine acyltransferase 3. Genes, record 10162. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10162

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Gene

Symbol
LPCAT3
HGNC
Name
lysophosphatidylcholine acyltransferase 3
HGNC
NCBI Gene ID
10162
NCBI Gene
HGNC ID
HGNC:30244
HGNC
Ensembl
ENSG00000111684
NCBI Gene
Aliases
C3F, LPCAT, LPLAT 5, LPLAT12, LPSAT, MBOAT5, OACT5, nessy
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q6P1A2Lysophospholipid acyltransferase 54870Ensembl, GeneID, HGNC

Source UniProt

Patents27

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1452144Q6P1A2Espacenet
EP 4650780 A22025-11-191885Q6P1A2Espacenet
EP 4641201 A22025-10-291473Q6P1A2Espacenet
JP 2025529142 A2025-09-042412Q6P1A2Espacenet
US 12371689 B22025-07-292412Q6P1A2Espacenet
JP 2025517969 A2025-06-121473Q6P1A2Espacenet
JP 2025517970 A2025-06-121885Q6P1A2Espacenet
US 11446398 B22022-09-2047881Q6P1A2Espacenet
US 11400116 B22022-08-023362Q6P1A2Espacenet
JP 2022524081 A2022-04-27150852Q6P1A2Espacenet

1 to 10 of 27

See all 27 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants654

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleLPCAT3 papersNewest fiscal year
P30CA016672Cancer Center Support Grant82025
R01NS076511Lipid Imaging in Traumatic Brain Injury by High Resolution GCIB-secondary Ion Mass Spectrometry82025
P30DK063491Diabetes Research Center (DRC)62025
P30CA008748Cancer Center Support Grant52025
R01GM122923Characterizing the Regulation of Ferroptosis42025
P30DK020572Michigan Diabetes Research Center (MDRC)32025
P30DK020579Diabetes Research Center32025
P30DK056341Washington University Nutrition Obesity Research Center32025
R01CA204232Ferroptosis, Cellular Metabolism, and Cancer32025
R01CA247992Targeting ferroptosis in radioresistance in lung cancer: mechanisms and preclinical translation32025

1 to 10 of 654Source NIH's project files

See all 654 nih grants

Papers1,424

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Pharmacological targeting of ferroptosis in cancer: mechanisms, tumor immunity, and translational challenges.Pharmacol Rep202642789241PubTator, text miningPubMed
Biochanin A promotes KLF6 stabilization to induce ferroptosis and suppress colorectal cancer progression.Cell Signal202642754129PubTator, text miningPubMed
IL1B-high macrophages promote ferroptosis-like lipid peroxidation injury in Crohn's disease intestinal epithelium.Redox Biol202642748656PubTator, text miningPubMed
Ginsenoside Rb1 alleviates AS co-depression disease by targeting the LPCAT3 and modulating the ACSL4/LPCAT3/ALOX15 ferroptosis pathway.Phytomedicine202642710215PubTator, text miningPubMed
DNA methylation-mediated silencing of MALAT1 promotes dexamethasone-induced growth plate chondrocyte ferroptosis via miR-124-3p/LPCAT3.J Bioenerg Biomembr202642709252PubTator, text miningPubMed
LPCAT3 is essential for leukemia progression and represents a therapeutic vulnerability in AML.Blood Sci202642699430PubTator, text miningPubMed
Ferroptosis in Ischemic Stroke: Insights from Natural Product Treatment and Future Directions.Drug Des Devel Ther202642666732PubTator, text miningPubMed
Dual Roles of Natural Products in Regulating Ferroptosis in Acute and Chronic Liver Diseases: A Review.Oxid Med Cell Longev202642610514PubTator, text miningPubMed
Rhubarb extract attenuates periodontitis by modulating an MMP3-associated inflammatory-ferroptotic axis: Integrated multi-omics analysis and experimental validation.Phytomedicine202642501548PubTator, text miningPubMed
NSD2 is a critical regulator of Erastin-induced ferroptosis in keratinocytes.Free Radic Biol Med202642462913PubTator, text miningPubMed

1 to 10 of 1,424

See all 1,424 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/10162

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