ConductScience.org, home

Library / Genes

ADAM10: ADAM metallopeptidase domain 10

1 protein, 125 patents, 0 drugs, 0 trials, 3,560 NIH grants and 6,339 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolADAM10HGNC
NameADAM metallopeptidase domain 10HGNC
NCBI Gene ID102NCBI Gene
HGNC IDHGNC:188HGNC
EnsemblENSG00000137845NCBI Gene
AliasesAD10, AD18, CD156C, CD156c, CDw156, HsT18717, MADM, RAK, kuzNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
O14672Disintegrin and metalloproteinase domain-containing protein 107483Ensembl, GeneID, HGNCUniProt

Patents 125

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1436382O14672Espacenet
JP 2025172069 A2025-11-20331O14672Espacenet
EP 4650780 A22025-11-191803O14672Espacenet
EP 4641201 A22025-10-291387O14672Espacenet
JP 2025147176 A2025-10-06235O14672Espacenet
JP 2025529142 A2025-09-04261O14672Espacenet
JP 2025529142 A2025-09-045368O14672Espacenet
US 12384828 B22025-08-12206O14672Espacenet
US 12371689 B22025-07-29261O14672Espacenet
US 12371689 B22025-07-295368O14672Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 3560

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
U24AG021886National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD)222,025NIH's project files
P30CA008748Cancer Center Support Grant162,025NIH's project files
P01AG026276Antecedent Biomarkers for Alzheimer Disease: The Adult Children Study142,025NIH's project files
P30CA047904Cancer Center Support Grant92,025NIH's project files
P30CA016059Massey Cancer Center - Cancer Center Support Grant82,025NIH's project files
P30AG072975Rush Alzheimer's Disease Research Center72,025NIH's project files
P30CA016087Cancer Center Support Grant72,025NIH's project files
P30CA016672Cancer Center Support Grant72,025NIH's project files
U19AG032438Bridge Funding for Dominantly Inherited Alzheimer Network72,025NIH's project files
P30AG066511Goizueta Alzheimer's Disease Research Center62,025NIH's project files

Papers 6339

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42826722PubTator, text miningPubMed
42824924PubTator, text miningPubMed
42818224PubTator, text miningPubMed
42785662PubTator, text miningPubMed
42758762PubTator, text miningPubMed
42723080PubTator, text miningPubMed
42714761PubTator, text miningPubMed
42693342PubTator, text miningPubMed
42686974PubTator, text miningPubMed
42679005PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license