Gene · 10209
EIF1: eukaryotic translation initiation factor 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. EIF1: eukaryotic translation initiation factor 1. Genes, record 10209. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10209
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P41567 | Eukaryotic translation initiation factor 1 | 113 | 15 | Ensembl, GeneID, HGNC |
Source UniProt
Patents42
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| US 11564998 B2 | 2023-01-31 | 8241 | P41567 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 28594 | P41567 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 131565 | P41567 | Espacenet |
| US 11078247 B2 | 2021-08-03 | 3449 | P41567 | Espacenet |
| WO 2020043864 A1 | 2020-03-05 | 773 | P41567 | Espacenet |
| US 10463751 B2 | 2019-11-05 | 8241 | P41567 | Espacenet |
| JP 2018023373 A | 2018-02-15 | 30968 | P41567 | Espacenet |
| US 9572897 B2 | 2017-02-21 | 8241 | P41567 | Espacenet |
| US 9303079 B2 | 2016-04-05 | 8241 | P41567 | Espacenet |
| JP 2015228843 A | 2015-12-21 | 348 | P41567 | Espacenet |
1 to 10 of 42
See all 42 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants961
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | EIF1 papers | Newest fiscal year |
|---|---|---|---|
| ZIAHD001004 | Molecular Mechanisms of Translational Control | 31 | 2025 |
| ZIAHD001010 | Mechanism and Regulation of Eukaryotic Protein Synthesis | 12 | 2025 |
| R35GM122602 | Mechanisms of eukaryotic translation and ribosome-associated mRNA surveillance and protein quality control | 10 | 2025 |
| P20GM103418 | Kansas IDeA Network of Biomedical Research Excellence 5 | 7 | 2025 |
| R01DK018381 | Studies on the structure of basement membranes | 6 | 2025 |
| ZIAHD008940 | Elucidating the Molecular Mechanics of Eukaryotic Translation Initiation and Its Control | 6 | 2025 |
| R35GM145306 | Dynamics of Translation | 5 | 2025 |
| P30CA015704 | Cancer Center Support Grant | 4 | 2025 |
| R25DK096999 | Undergraduate Discovery Science Experience in Renal Biology and Disease | 4 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 4 | 2025 |
1 to 10 of 961Source NIH's project files
See all 961 nih grantsPapers1,308
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Altered neuronal start codon stringency favors cap-independent repeat-associated non-AUG translation. | Nucleic Acids Res | 2026 | 42725432 | PubTator, text mining | PubMed |
| EIF1 coordinates transcriptomic and splicing networks associated with cell cycle dysregulation in diabetic retinopathy. | PLoS One | 2026 | 42691050 | PubTator, text mining | PubMed |
| Altered neuronal start codon stringency favors cap-independent repeat-associated non-AUG translation. | bioRxiv | 2026 | 42539252 | PubTator, text mining | PubMed |
| Translation initiation by the Kozak mRNA sequence is based on a conformational readout on the ribosome. | Nat Commun | 2026 | 42420270 | PubTator, text mining | PubMed |
| Elongationless start-stop elements are stress-resilient translation gates that are more repressive than uTranslons. | Nucleic Acids Res | 2026 | 42411409 | PubTator, text mining | PubMed |
| The Multiple Roles and Targeting Strategies of LonP1 in the Occurrence and Development of Cancer. | Biofactors | 2026 | 42219609 | PubTator, text mining | PubMed |
| Computational Approach Improves Diagnostic Performance Based on Tumor-Associated Autoantibodies in Esophageal Squamous Cell Carcinoma. | Comput Struct Biotechnol J | 2026 | 41971943 | PubTator, text mining | PubMed |
| The enigma of nuclear FMRP: facts and myths. | Front Cell Dev Biol | 2026 | 41768999 | PubTator, text mining | PubMed |
| Isogenic cortical organoids enable precision targeting of APP variant-specific pathways in Alzheimer's disease. | bioRxiv | 2026 | 41757078 | PubTator, text mining | PubMed |
| CELF1 is a non-canonical eIF4E binding protein that promotes translation of epithelial-mesenchymal transition effector mRNAs. | Nucleic Acids Res | 2026 | 41755641 | PubTator, text mining | PubMed |
1 to 10 of 1,308
See all 1,308 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/10209
GET https://conductscience.org/api/genes/v1/10209/patents?page=2