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Gene · 10209

EIF1: eukaryotic translation initiation factor 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. EIF1: eukaryotic translation initiation factor 1. Genes, record 10209. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10209

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Gene

Symbol
EIF1
HGNC
Name
eukaryotic translation initiation factor 1
HGNC
NCBI Gene ID
10209
NCBI Gene
HGNC ID
HGNC:3249
HGNC
Ensembl
ENSG00000173812
NCBI Gene
Aliases
A121, EIF-1, EIF1A, ISO1, SUI1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P41567Eukaryotic translation initiation factor 111315Ensembl, GeneID, HGNC

Source UniProt

Patents42

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
US 11564998 B22023-01-318241P41567Espacenet
US 11446398 B22022-09-2028594P41567Espacenet
JP 2022524081 A2022-04-27131565P41567Espacenet
US 11078247 B22021-08-033449P41567Espacenet
WO 2020043864 A12020-03-05773P41567Espacenet
US 10463751 B22019-11-058241P41567Espacenet
JP 2018023373 A2018-02-1530968P41567Espacenet
US 9572897 B22017-02-218241P41567Espacenet
US 9303079 B22016-04-058241P41567Espacenet
JP 2015228843 A2015-12-21348P41567Espacenet

1 to 10 of 42

See all 42 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants961

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleEIF1 papersNewest fiscal year
ZIAHD001004Molecular Mechanisms of Translational Control312025
ZIAHD001010Mechanism and Regulation of Eukaryotic Protein Synthesis122025
R35GM122602Mechanisms of eukaryotic translation and ribosome-associated mRNA surveillance and protein quality control102025
P20GM103418Kansas IDeA Network of Biomedical Research Excellence 572025
R01DK018381Studies on the structure of basement membranes62025
ZIAHD008940Elucidating the Molecular Mechanics of Eukaryotic Translation Initiation and Its Control62025
R35GM145306Dynamics of Translation52025
P30CA015704Cancer Center Support Grant42025
R25DK096999Undergraduate Discovery Science Experience in Renal Biology and Disease42025
UL1TR001863Yale Clinical and Translational Science Award42025

1 to 10 of 961Source NIH's project files

See all 961 nih grants

Papers1,308

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Altered neuronal start codon stringency favors cap-independent repeat-associated non-AUG translation.Nucleic Acids Res202642725432PubTator, text miningPubMed
EIF1 coordinates transcriptomic and splicing networks associated with cell cycle dysregulation in diabetic retinopathy.PLoS One202642691050PubTator, text miningPubMed
Altered neuronal start codon stringency favors cap-independent repeat-associated non-AUG translation.bioRxiv202642539252PubTator, text miningPubMed
Translation initiation by the Kozak mRNA sequence is based on a conformational readout on the ribosome.Nat Commun202642420270PubTator, text miningPubMed
Elongationless start-stop elements are stress-resilient translation gates that are more repressive than uTranslons.Nucleic Acids Res202642411409PubTator, text miningPubMed
The Multiple Roles and Targeting Strategies of LonP1 in the Occurrence and Development of Cancer.Biofactors202642219609PubTator, text miningPubMed
Computational Approach Improves Diagnostic Performance Based on Tumor-Associated Autoantibodies in Esophageal Squamous Cell Carcinoma.Comput Struct Biotechnol J202641971943PubTator, text miningPubMed
The enigma of nuclear FMRP: facts and myths.Front Cell Dev Biol202641768999PubTator, text miningPubMed
Isogenic cortical organoids enable precision targeting of APP variant-specific pathways in Alzheimer's disease.bioRxiv202641757078PubTator, text miningPubMed
CELF1 is a non-canonical eIF4E binding protein that promotes translation of epithelial-mesenchymal transition effector mRNAs.Nucleic Acids Res202641755641PubTator, text miningPubMed

1 to 10 of 1,308

See all 1,308 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/10209

GET https://conductscience.org/api/genes/v1/10209/patents?page=2