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Gene · 10211

FLOT1: flotillin 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. FLOT1: flotillin 1. Genes, record 10211. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10211

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Gene

Symbol
FLOT1
HGNC
Name
flotillin 1
HGNC
NCBI Gene ID
10211
NCBI Gene
HGNC ID
HGNC:3757
HGNC
Ensembl
ENSG00000137312
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O75955Flotillin-14272Ensembl, GeneID, HGNC

Source UniProt

Patents80

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1446421O75955Espacenet
JP 2026004568 A2026-01-1446422O75955Espacenet
JP 2026004568 A2026-01-1446423O75955Espacenet
JP 2026004568 A2026-01-1446447O75955Espacenet
JP 2026004568 A2026-01-1446457O75955Espacenet
EP 4650780 A22025-11-199771O75955Espacenet
EP 4641202 A22025-10-295656O75955Espacenet
JP 2025517970 A2025-06-129771O75955Espacenet
KR 1020250017231 A2025-02-045656O75955Espacenet
EP 4299137 A22024-01-037O75955Espacenet

1 to 10 of 80

See all 80 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,742

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleFLOT1 papersNewest fiscal year
P30CA016672Cancer Center Support Grant102025
P30CA068485Cancer Center Support Grant82025
P30DK058404Molecular and Cellular Basis for Digestive Diseases82025
P30EY008126Core Grant in Vision Research82025
P30CA060553The Robert H. Lurie Comprehensive Cancer Center52025
P30CA076292Moffitt Cancer Center Support Grant52025
P30DK020593Vanderbilt Diabetes Research Center52025
P30CA008748Cancer Center Support Grant42025
P30CA010815Consolidated Basic Cancer Research Program42025
P30CA016056Roswell Park Cancer Center Support Grant42025

1 to 10 of 1,742Source NIH's project files

See all 1,742 nih grants

Papers2,417

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Inducing oxidative stress by targeting the cholesterol biosynthesis pathway augments the efficacy of bortezomib in multiple myeloma.Free Radic Biol Med202642767467PubTator, text miningPubMed
Extracellular Vesicles in Cardiovascular Disease: Intercellular Signaling, Liquid Biopsy Biomarkers, and Therapeutic Translation.Circ Res202642594169PubTator, text miningPubMed
Identification of common diagnostic biomarkers and immune landscapes in sepsis and acute kidney injury: a transcriptomic study integrating machine learning and single-cell analysis.Front Genet202642553929PubTator, text miningPubMed
Plasma Proteins and Genes Associated with Protein and Risks for Diabetic Foot Diseases Identified Using Multi- Ornics and Mendelian Randomization Analysis.Curr Med Chem202642509680PubTator, text miningPubMed
Ovarian Cancer Diagnosis and Chemoresistance Prediction Model Based on cfRNA Molecular Signature.Adv Sci (Weinh)202642467997PubTator, text miningPubMed
FLOT1 and EEF1D: ac4C-related genes bridging Alzheimer's disease and sleep deprivation.Front Aging Neurosci202642395345PubTator, text miningPubMed
Endogenous Peptide Derived from c-Cbl-Associated Protein Counteracts Its Inhibitory Effect on Enteric Neural Crest Cell Colonization in Hirschsprung Disease.J Neurosci202642392872PubTator, text miningPubMed
Microglia-derived exosomal miR-31-5p promotes type 2 diabetic retinopathy by impairing physiological angiogenesis homeostasis.Free Radic Biol Med202642392284PubTator, text miningPubMed
RETRACTION: FLOT1 promotes tumor development, induces epithelial-mesenchymal transition, and modulates the cell cycle by regulating the Erk/Akt signaling pathway in lung adenocarcinoma.Thorac Cancer202642309829PubTator, text miningPubMed
Small extracellular vesicle-mediated transfer of HPV16 transcripts from Ca Ski cells increases proliferation of HPV-negative recipient cancer cells.Cell Commun Signal202642298561PubTator, text miningPubMed

1 to 10 of 2,417

See all 2,417 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/10211

GET https://conductscience.org/api/genes/v1/10211/patents?page=2