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Gene · 10219

KLRG1: killer cell lectin like receptor G1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. KLRG1: killer cell lectin like receptor G1. Genes, record 10219. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10219

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Gene

Symbol
KLRG1
HGNC
Name
killer cell lectin like receptor G1
HGNC
NCBI Gene ID
10219
NCBI Gene
HGNC ID
HGNC:6380
HGNC
Ensembl
ENSG00000139187
NCBI Gene
Aliases
2F1, CLEC15A, MAFA, MAFA-2F1, MAFA-L, MAFA-LIKE
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q96E93Killer cell lectin-like receptor subfamily G member 11951Ensembl, GeneID, HGNC

Source UniProt

Patents43

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026082951 A2026-05-195Q96E93Espacenet
JP 2026004568 A2026-01-1450777Q96E93Espacenet
EP 4641202 A22025-10-29127Q96E93Espacenet
JP 2025147176 A2025-10-0615256Q96E93Espacenet
EP 4619424 A22025-09-2414Q96E93Espacenet
JP 2025529142 A2025-09-042320Q96E93Espacenet
US 12371689 B22025-07-292320Q96E93Espacenet
JP 2025092554 A2025-06-196Q96E93Espacenet
JP 2025028160 A2025-02-2815256Q96E93Espacenet
KR 1020250017231 A2025-02-04127Q96E93Espacenet

1 to 10 of 43

See all 43 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,977

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleKLRG1 papersNewest fiscal year
U19AI082630Durable Alteration of the Human Immune system after Infection or Immunotherapy242025
P30CA008748Cancer Center Support Grant222025
P30CA016672Cancer Center Support Grant212025
UL1TR001863Yale Clinical and Translational Science Award142025
R01AI066232Regulation of memory CD8 T cell development132025
R01AI100874The natural killer cell response against mouse cytomegalovirus infection132025
U19AI057266Vaccine and Infection Induced Immunity in the Young and Aged132025
P30CA016058Cancer Center Support Grant122025
U01AI095608Regulation of mucosal immunity by neuronal pathways122025
P01AI108545Synergies among inhibitory receptors in tolerance and disease112025

1 to 10 of 2,977Source NIH's project files

See all 2,977 nih grants

Papers3,260

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
The Impact of Aerobic Exercise on Circulating T-Cells and NK-Cells in Colorectal Cancer Survivors: A Secondary Analysis of a Randomized Trial.Cancer Control202642808444PubTator, text miningPubMed
CD43 is a checkpoint against KLRG-1+CD49dhi effector CD8+ T cell formation.Transpl Immunol202642785691PubTator, text miningPubMed
Myositis with nemaline rods: Clinical features and treatment outcomes.J Neurol Sci202642700620PubTator, text miningPubMed
Inclusion body myositis: new insights into pathogenesis and therapeutic perspectives.Curr Opin Rheumatol202642682173PubTator, text miningPubMed
Neuromedin U 'innervation' reprograms myeloid immunosuppression in neuroendocrine prostate cancer.Oncogene202642675222PubTator, text miningPubMed
T-cell immunosenescence limits CD19 CAR T-cell function in chronic lymphocytic leukemia.Blood202642636161PubTator, text miningPubMed
BioPathfinder: Evidence-guided multi-agent platform enables hypothesis discovery for CAR-T engineering.bioRxiv202642619779PubTator, text miningPubMed
Paradigm shift in the pathomechanisms and treatment of inclusion body myositis: at the crossroads of cell-autonomous muscle degeneration and immune activation.Curr Opin Neurol202642615630PubTator, text miningPubMed
Eradication of pre-clinical prostate tumors by a lentiviral vector-based immunotherapy.Mol Ther Oncol202642598525PubTator, text miningPubMed
Multiomics Dissection Reveals Natural Killer Cell-CD8+ T-cell Cooperation in Shaping an Immunostimulatory Tumor Microenvironment.Cancer Res202642545372PubTator, text miningPubMed

1 to 10 of 3,260

See all 3,260 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/10219

GET https://conductscience.org/api/genes/v1/10219/patents?page=2