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CDK7: cyclin dependent kinase 7
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Gene · 1022

Papers3,996

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

1 to 20 of 3,996

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TitleJournalYearPMIDFound bySource
Machine learning-guided discovery of a novel natural CDK7 inhibitor for triple-negative breast cancer.Comput Biol Chem202642826577PubTator, text miningPubMed
CDK7, CDK9, or CDK11 inhibition reduces neutrophil-driven inflammation and tissue damage in experimental autoimmune models.Cell Commun Signal202642823736PubTator, text miningPubMed
Sensitizing tumor response to topoisomerase I antibody-drug conjugate by selective CDK7 inhibition.Sci Adv202642814835PubTator, text miningPubMed
Association of miR-199a-3p and CDK7 expression with clinicopathological features of breast cancer.Mol Biol Rep202642804014PubTator, text miningPubMed
Transcriptomic Plasticity and Its Spatial Architecture Shape Melanoma Response to Immunotherapy and Its Combination With BRAF/MEKi.J Clin Oncol202642771837PubTator, text miningPubMed
Correction: Novel covalent CDK7 inhibitor potently induces apoptosis in acute myeloid leukemia and synergizes with Venetoclax.J Exp Clin Cancer Res202642760550PubTator, text miningPubMed
MNAT1 in gastrointestinal cancers: mechanistic insights and therapeutic strategies-a narrative review.J Gastrointest Oncol202642703445PubTator, text miningPubMed
FAIMS-GPF XL-MS: crosslinking-mass spectrometry based on gas-phase fractionation.Nat Commun202642642374PubTator, text miningPubMed
Targeting CDK7 to overcome hypomethylating agent resistance in acute myeloid leukemia.Blood Res202642635915PubTator, text miningPubMed
Cell cycle regulators contribute to extravillous trophoblast cell differentiation and function.Hum Reprod202642630068PubTator, text miningPubMed
Pharmacological inhibition of CDK7 and CDK9 suppresses gastrointestinal (colon) cancer progression through modulation of stemness, epithelial-mesenchymal transition, and chemoresistance.Naunyn Schmiedebergs Arch Pharmacol202642624930PubTator, text miningPubMed
Discovery of ZJC-11 as a Novel Selective CDK7 Inhibitor for Treating Triple-Negative Breast Cancer by Inducing Cell Senescence.J Med Chem202642593900PubTator, text miningPubMed
Erratum to "Development of a novel PI3Kα/CDK7 potent hybrid inhibitor for Cancer treatment" [Bioorg. Med. Chem. Lett. 140 (2026) 130738].Bioorg Med Chem Lett202642575810PubTator, text miningPubMed
Yorkie/YAP Interactors: Fine-Tuning the Hippo Pathway Output.Cold Spring Harb Perspect Biol202642575696PubTator, text miningPubMed
[Research Progress of CDK Inhibitors in Acute Myeloid Leukemia --Review].Zhongguo Shi Yan Xue Ye Xue Za Zhi202642544683PubTator, text miningPubMed
Integrative analysis of YTHDC1 phosphoproteome unveils its phosphomodulatory network linked to splicing and tumorigenesis.Front Bioinform202642519490PubTator, text miningPubMed
Integrative Analysis Identified an Eight-Gene Risk Signature Linked to CDK7 and Explored Its Association with HCC Progression via RelA Phosphorylation.Oncol Res202642500561PubTator, text miningPubMed
Author Correction: Resistance to CDK7 inhibitors directed by acquired mutation of a conserved residue in cancer cells.EMBO J202642469445PubTator, text miningPubMed
Development of a novel PI3Kα/CDK7 potent hybrid inhibitor for Cancer treatment.Bioorg Med Chem Lett202642468711PubTator, text miningPubMed
Evaluation of the anti-apoptotic, anti-platelet aggregation, and pro-angiogenic properties of Naoshuantong capsule in ischemic stroke: insights from network pharmacology and animal experiments.J Tradit Chin Med202642365410PubTator, text miningPubMed

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Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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