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Gene · 10225

CD96: CD96 molecule

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CD96: CD96 molecule. Genes, record 10225. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10225

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Gene

Symbol
CD96
HGNC
Name
CD96 molecule
HGNC
NCBI Gene ID
10225
NCBI Gene
HGNC ID
HGNC:16892
HGNC
Ensembl
ENSG00000153283
NCBI Gene
Aliases
TACTILE
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P40200T-cell surface protein tactile5851Ensembl, GeneID, HGNC

Source UniProt

Patents43

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1440657P40200Espacenet
EP 4641201 A22025-10-292769P40200Espacenet
EP 4619424 A22025-09-2496P40200Espacenet
JP 2025529142 A2025-09-04848P40200Espacenet
US 12371689 B22025-07-29848P40200Espacenet
US 12365732 B22025-07-221P40200Espacenet
JP 2025517969 A2025-06-122769P40200Espacenet
WO 2025015322 A12025-01-169891P40200Espacenet
JP 2024536217 A2024-10-043P40200Espacenet
EP 4408443 A12024-08-073P40200Espacenet

1 to 10 of 43

See all 43 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants840

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCD96 papersNewest fiscal year
P30CA008748Cancer Center Support Grant102025
P01CA111412NK cells, their receptors and cancer therapy82025
P01CA065493Off-the-Shelf Immune Effector Cells for Hematological Malignancies72025
P30CA016672Cancer Center Support Grant72025
P30CA006973Regional Oncology Research Center42025
P30CA016058Cancer Center Support Grant42025
P30CA021765Cancer Center Support Grant (CCSG)42025
R01HL117913The NOTCH Signaling Pathway in Large Vessel Vasculitis42025
U19AI057229Understanding Influenza and SARS-CoV-2 vaccine responses, in vivo and in vitro42025
U19AI057266Vaccine and Infection Induced Immunity in the Young and Aged42025

1 to 10 of 840Source NIH's project files

See all 840 nih grants

Papers1,736

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Bioinformatics Analysis of T-cell Exhaustion Genes in Pediatric Allergic Rhinitis and their Clinical Diagnostic Significance.Endocr Metab Immune Disord Drug Targets202642813621PubTator, text miningPubMed
Natural Killer Cell-Derived Extracellular Vesicle Preparations Demonstrate Potent Antitumor Activity Against Human Glioblastoma In Vitro and In Vivo.J Extracell Biol202642788040PubTator, text miningPubMed
Immune checkpoint knockout screen reveals TIGIT-CD155 interaction as a significant modulator of adapter CAR-T cell function in acute myeloid leukemia.Oncoimmunology202642750591PubTator, text miningPubMed
Identification of core differentially expressed genes for respiratory syncytial virus infection.Glob Med Genet202642729716PubTator, text miningPubMed
The PVR-TIGIT/CD96/CD226 axis: a novel immune checkpoint target in ovarian cancer.Front Immunol202642694449PubTator, text miningPubMed
A Phase I First-Time-in-Human, Open-label Study of Nelistotug Administered to Patients with Advanced Solid Tumors.Clin Cancer Res202642658188PubTator, text miningPubMed
CD96 marks a phenotypically distinct checkpoint-associated HCV-specific CD8+ T-cell subset featuring memory-associated states.Front Immunol202642516367PubTator, text miningPubMed
A novel Vδ1 engager targeting CD19 enhances human Vδ1 γδ T cell responses against CLL and CD19+ hematological malignancies.J Immunol202642455847PubTator, text miningPubMed
Single-cell RNA Sequencing Reveals A Tumor-Promoting Role of EGR1+CD4+ T Cells in Papillary Thyroid Cancer.Genomics Proteomics Bioinformatics202642412534PubTator, text miningPubMed
Spatial analyses implicate high stromal tumour-infiltrating CD8+ lymphocytes as a negative predictive marker for chemotherapy in estrogen receptor-positive breast cancer.Nat Commun202642337235PubTator, text miningPubMed

1 to 10 of 1,736

See all 1,736 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/10225

GET https://conductscience.org/api/genes/v1/10225/patents?page=2