Gene · 10241
CALCOCO2: calcium binding and coiled-coil domain 2
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. CALCOCO2: calcium binding and coiled-coil domain 2. Genes, record 10241. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10241
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q13137 | Calcium-binding and coiled-coil domain-containing protein 2 | 446 | 10 | Ensembl, GeneID, HGNC |
Source UniProt
Patents28
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4650780 A2 | 2025-11-19 | 1720 | Q13137 | Espacenet |
| EP 4640849 A2 | 2025-10-29 | 203 | Q13137 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 1317 | Q13137 | Espacenet |
| JP 2025519096 A | 2025-06-24 | 203 | Q13137 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 1317 | Q13137 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 1720 | Q13137 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 10561 | Q13137 | Espacenet |
| US 11666661 B2 | 2023-06-06 | 8 | Q13137 | Espacenet |
| US 11564998 B2 | 2023-01-31 | 4866 | Q13137 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 10561 | Q13137 | Espacenet |
1 to 10 of 28
See all 28 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,053
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | CALCOCO2 papers | Newest fiscal year |
|---|---|---|---|
| P20GM121176 | Autophagy, Inflammation and Metabolism (AIM) in Disease Center - Phase 2. | 14 | 2025 |
| R37AI042999 | Pattern Recognition Receptors and Autophagy in Mtb Control in AIDS | 11 | 2025 |
| R35GM131919 | The mechanism and regulation of autophagy | 9 | 2025 |
| P30DK043351 | Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital | 8 | 2025 |
| P30CA010815 | Consolidated Basic Cancer Research Program | 6 | 2025 |
| R01CA126792 | Autophagy and Pro-metastatic Differentiation | 6 | 2025 |
| ZIANS003123 | Role of mitochondria in neurodegenerative diseases | 6 | 2025 |
| ZIANS003127 | Mechanisms of Autophagy | 6 | 2025 |
| R01NS110395 | Endolysosomal Proteome Landscapes Through the Lens of Neurodegenerative Risk Alleles | 5 | 2025 |
| P01AI063302 | The intersection of innate and adaptive immunity to intracellular pathogens | 4 | 2025 |
1 to 10 of 1,053Source NIH's project files
See all 1,053 nih grantsPapers1,742
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| ULK1-dependent autophagy initiation promotes MHC-I degradation and immune evasion in HPV-positive head and neck cancer. | Cancer Immunol Res | 2026 | 42803943 | PubTator, text mining | PubMed |
| CRISPR and yeast two-hybrid screens identify CD81 as a proviral host factor for PRRSV. | J Virol | 2026 | 42734356 | PubTator, text mining | PubMed |
| Mitochondrial damage and post-translational modifications in radiation-induced heart disease: mechanisms and emerging therapeutic targets. | Front Pediatr | 2026 | 42694352 | PubTator, text mining | PubMed |
| RNF187 inhibits porcine reproductive and respiratory syndrome virus replication by recruiting the autophagy receptor NDP52 to degrade nsp12. | Vet Res | 2026 | 42542550 | PubTator, text mining | PubMed |
Autophagy-Related Gene-Set Signals in the Genetic Architecture of Obsessive-Compulsive Disorder: A Hypothesis-Generating Link to Nicotinamide Adenine Dinucleotide-Associated Cellular Maintenance Biology. | Cureus | 2026 | 42502305 | PubTator, text mining | PubMed |
| Multiparametric flow cytometry immune profiling of pulmonary and extra-pulmonary tuberculosis reveals distinct blood-based biomarker signatures. | Tuberculosis (Edinb) | 2026 | 42501466 | PubTator, text mining | PubMed |
| HTLV-1 Tax induces PINK1-PRKN/parkin-dependent mitophagy to mitigate activation of the CGAS-STING1 pathway. | Autophagy | 2026 | 42483932 | PubTator, text mining | PubMed |
| Antibody-dependent xenophagy targets viruses and bacteria for destruction. | Autophagy | 2026 | 42418235 | PubTator, text mining | PubMed |
| Tegument protein UL16 of herpes simplex virus 1 suppresses the innate immune response by downregulating MAVS abundance via mitophagy. | Autophagy | 2026 | 42391028 | PubTator, text mining | PubMed |
| Beyond autophagic flux: selective autophagy adaptors and cargo prioritization in cardiac disease. | Cardiol Plus | 2026 | 42369864 | PubTator, text mining | PubMed |
1 to 10 of 1,742
See all 1,742 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/10241
GET https://conductscience.org/api/genes/v1/10241/patents?page=2