ConductScience.org, home

Gene · 10241

CALCOCO2: calcium binding and coiled-coil domain 2

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. CALCOCO2: calcium binding and coiled-coil domain 2. Genes, record 10241. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10241

On this page

Gene

Symbol
CALCOCO2
HGNC
Name
calcium binding and coiled-coil domain 2
HGNC
NCBI Gene ID
10241
NCBI Gene
HGNC ID
HGNC:29912
HGNC
Ensembl
ENSG00000136436
NCBI Gene
Aliases
MGC17318, NDP52
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q13137Calcium-binding and coiled-coil domain-containing protein 244610Ensembl, GeneID, HGNC

Source UniProt

Patents28

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-191720Q13137Espacenet
EP 4640849 A22025-10-29203Q13137Espacenet
EP 4641201 A22025-10-291317Q13137Espacenet
JP 2025519096 A2025-06-24203Q13137Espacenet
JP 2025517969 A2025-06-121317Q13137Espacenet
JP 2025517970 A2025-06-121720Q13137Espacenet
JP 2025062604 A2025-04-1410561Q13137Espacenet
US 11666661 B22023-06-068Q13137Espacenet
US 11564998 B22023-01-314866Q13137Espacenet
US 11446398 B22022-09-2010561Q13137Espacenet

1 to 10 of 28

See all 28 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,053

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCALCOCO2 papersNewest fiscal year
P20GM121176Autophagy, Inflammation and Metabolism (AIM) in Disease Center - Phase 2.142025
R37AI042999Pattern Recognition Receptors and Autophagy in Mtb Control in AIDS112025
R35GM131919The mechanism and regulation of autophagy92025
P30DK043351Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital82025
P30CA010815Consolidated Basic Cancer Research Program62025
R01CA126792Autophagy and Pro-metastatic Differentiation62025
ZIANS003123Role of mitochondria in neurodegenerative diseases62025
ZIANS003127Mechanisms of Autophagy62025
R01NS110395Endolysosomal Proteome Landscapes Through the Lens of Neurodegenerative Risk Alleles52025
P01AI063302The intersection of innate and adaptive immunity to intracellular pathogens42025

1 to 10 of 1,053Source NIH's project files

See all 1,053 nih grants

Papers1,742

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
ULK1-dependent autophagy initiation promotes MHC-I degradation and immune evasion in HPV-positive head and neck cancer.Cancer Immunol Res202642803943PubTator, text miningPubMed
CRISPR and yeast two-hybrid screens identify CD81 as a proviral host factor for PRRSV.J Virol202642734356PubTator, text miningPubMed
Mitochondrial damage and post-translational modifications in radiation-induced heart disease: mechanisms and emerging therapeutic targets.Front Pediatr202642694352PubTator, text miningPubMed
RNF187 inhibits porcine reproductive and respiratory syndrome virus replication by recruiting the autophagy receptor NDP52 to degrade nsp12.Vet Res202642542550PubTator, text miningPubMed
Autophagy-Related Gene-Set Signals in the Genetic Architecture of Obsessive-Compulsive Disorder: A Hypothesis-Generating Link to Nicotinamide Adenine Dinucleotide-Associated Cellular Maintenance Biology.
Cureus202642502305PubTator, text miningPubMed
Multiparametric flow cytometry immune profiling of pulmonary and extra-pulmonary tuberculosis reveals distinct blood-based biomarker signatures.Tuberculosis (Edinb)202642501466PubTator, text miningPubMed
HTLV-1 Tax induces PINK1-PRKN/parkin-dependent mitophagy to mitigate activation of the CGAS-STING1 pathway.Autophagy202642483932PubTator, text miningPubMed
Antibody-dependent xenophagy targets viruses and bacteria for destruction.Autophagy202642418235PubTator, text miningPubMed
Tegument protein UL16 of herpes simplex virus 1 suppresses the innate immune response by downregulating MAVS abundance via mitophagy.Autophagy202642391028PubTator, text miningPubMed
Beyond autophagic flux: selective autophagy adaptors and cargo prioritization in cardiac disease.Cardiol Plus202642369864PubTator, text miningPubMed

1 to 10 of 1,742

See all 1,742 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/10241

GET https://conductscience.org/api/genes/v1/10241/patents?page=2