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GPHN: gephyrin
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Gene · 10243

Papers1,523

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

1 to 20 of 1,523

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TitleJournalYearPMIDFound bySource
Redox-dependent synaptic clustering of gephyrin.Nat Commun202642693144PubTator, text miningPubMed
WNK-dependent phosphorylation of gephyrin tunes GABAA receptors at inhibitory synapses and modulates anxiety behavior.Proc Natl Acad Sci U S A202642640800PubTator, text miningPubMed
Maternal immune activation induces sex-dependent metabolic, epigenetic and GABAergic trajectories in the hippocampus.Brain Behav Immun202642409184PubTator, text miningPubMed
Impaired gephyrin G-domain trimerization and phase separation in a patient with developmental epileptic encephalopathy.EMBO Mol Med202642380307PubTator, text miningPubMed
Gephyrin Neurological Autoimmunity.Ann Neurol202642307210PubTator, text miningPubMed
Phylogenetic based dissection of eukaryotic Mo-insertase functionality: From mechanism to complex assembly.PLoS One202642284359PubTator, text miningPubMed
Abnormal neuronal and synaptic morphology in Down syndrome brains reproduces in human isogenic cellular models.Cell Death Dis202642270579PubTator, text miningPubMed
Optical mapping reveals a higher level of large-scale structural variants in a family with paternally transmitted myotonic dystrophy and independent Parkinson's disease.J Pathol202642261605PubTator, text miningPubMed
Astrocyte-specific NRCAM deficiency promotes GABAergic synapse pruning to drive central sensitization in bone cancer pain.J Transl Med202642249478PubTator, text miningPubMed
Autophagic Pathway on GABARAP Involved in GABAA Receptor Trafficking.Neurochem Res202642225974PubTator, text miningPubMed
Neurexins contribute to inhibitory connectivity and dopamine neuron resilience in culture.Neuroscience202642162731PubTator, text miningPubMed
Coordinated Pre- and Postsynaptic Protein Dynamics Underlie Rapid Sema4D-Induced Inhibitory Synapse Assembly.eNeuro202642156167PubTator, text miningPubMed
Cryo-EM structures of higher order Gephyrin oligomers reveal principles of inhibitory postsynaptic scaffold organization.Nat Commun202641991925PubTator, text miningPubMed
Heterogeneity of monogenic epilepsy in loci, phenotypes, and treatment approaches.Neurol Sci202641912906PubTator, text miningPubMed
Weaker neuroligin 2-neurexin β1 interaction tethers membranes and recruits gephyrin at membrane junctions through clustering.Sci Adv202641824561PubTator, text miningPubMed
Liquid-liquid phase separation in neural development.Cell Mol Life Sci202641790295PubTator, text miningPubMed
Altered transposon element-derived genes distort oxygen-free radical scavenger systems in FXD.NAR Mol Med202641768973PubTator, text miningPubMed
Brain lipidomics for region-specific biomarker discovery in neurodegenerative diseases.Front Aging Neurosci202641757360PubTator, text miningPubMed
ZCCHC17: a target for synaptic dysfunction and neuronal excitability in Alzheimer's disease.Front Aging Neurosci202641743466PubTator, text miningPubMed
Proteome-Wide Analysis of Functional Phosphosites in the FGFR Family of Proteins: Insights from Large-Scale Phosphoproteomic Analysis.Proteomes202641718090PubTator, text miningPubMed

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Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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