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Gene · 10257

ABCC4: ATP binding cassette subfamily C member 4 (PEL blood group)

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ABCC4: ATP binding cassette subfamily C member 4 (PEL blood group). Genes, record 10257. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10257

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Gene

Symbol
ABCC4
HGNC
Name
ATP binding cassette subfamily C member 4 (PEL blood group)
HGNC
NCBI Gene ID
10257
NCBI Gene
HGNC ID
HGNC:55
HGNC
Ensembl
ENSG00000125257
NCBI Gene
Aliases
EST170205, MOAT-B, MOATB, MRP4
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O15439ATP-binding cassette sub-family C member 41,32525Ensembl, GeneID, HGNC

Source UniProt

Patents44

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1438423O15439Espacenet
EP 4641201 A22025-10-2924801O15439Espacenet
JP 2025529142 A2025-09-04202O15439Espacenet
US 12371689 B22025-07-29202O15439Espacenet
JP 2025517969 A2025-06-1224801O15439Espacenet
JP 2025062604 A2025-04-147733O15439Espacenet
JP 2023536814 A2023-08-307178O15439Espacenet
JP 2023519304 A2023-05-10106O15439Espacenet
KR 1020230049661 A2023-04-137161O15439Espacenet
KR 1020220160053 A2022-12-0591O15439Espacenet

1 to 10 of 44

See all 44 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,908

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleABCC4 papersNewest fiscal year
P30CA021765Cancer Center Support Grant (CCSG)432025
P30AI050410The University of North Carolina Center for AIDS Research212025
R01DK080834Inhibition of an Apical cAMP/cGMP Transporter (MRP4) in the Gut Induces Diarrhea162025
P30ES006694Southwest Environmental Health Sciences Center142025
P30DK034989Yale Liver Center122025
R35GM122576Mechanisms of Altered Hepatic Transport: Impact on Drug Therapy122025
P30CA016672Cancer Center Support Grant92025
R01CA194057Transporters and Medulloblastoma92025
ZIABC010030Biochemical Analysis of Multidrug Resistance-linked Transport Proteins92025
P30ES005022Rutgers Center for Environmental Exposure and Disease (CEED)82025

1 to 10 of 1,908Source NIH's project files

See all 1,908 nih grants

Papers3,557

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Associations of Genetic Variants in Uric Acid Transporter Genes With Salt Sensitivity, Longitudinal Blood Pressure Changes, and Incident Hypertension in Chinese Adults.J Clin Hypertens (Greenwich)202642745169PubTator, text miningPubMed
Phenotype-Specific Pharmacogenetic Patterns of Methotrexate Neurotoxicity in Pediatric Acute Lymphoblastic Leukemia.J Clin Med202642739879PubTator, text miningPubMed
Integrating machine learning and GWAS for variant prioritization in the INCIPE cohort highlights ABC transporter genes in chronic kidney disease.Front Genet202642733719PubTator, text miningPubMed
Exploratory Analysis of Glaucoma-Associated SNPs in a Colombian Cohort Highlights Potential Involvement of Oxidative, Vascular, and Neurodegenerative Pathways.Genes (Basel)202642650112PubTator, text miningPubMed
Prenatal caffeine exposure disrupts the fetal-placental-maternal bile acid circulation and its associated placental transport mechanisms.Food Chem Toxicol202642342146PubTator, text miningPubMed
Schistosoma japonicum histone acetyltransferase 1 (SjHAT1): A novel anti-schistosomal drug target.PLoS Pathog202642340953PubTator, text miningPubMed
Beyond cartilage degeneration: osteoarthritis as a systems failure of inflammation regulation.Front Med (Lausanne)202642292186PubTator, text miningPubMed
Genetic polymorphisms associated with therapeutic response and adverse effects to methotrexate in Taiwanese patients with rheumatoid arthritis: a real-world, hospital-based study.Sci Rep202642265358PubTator, text miningPubMed
ST-elevation myocardial infarction following de-escalation to aspirin monotherapy: evidence of residual platelet function MRP4 overexpression dependent case report.Eur Heart J Case Rep202642255179PubTator, text miningPubMed
Altered renal disposition of adefovir in metabolic dysfunction-associated steatohepatitis using the fast-food diet and thioacetamide-induced model to extrapolate renal secretion.Drug Metab Dispos202642208114PubTator, text miningPubMed

1 to 10 of 3,557

See all 3,557 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

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