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CDKN1A: cyclin dependent kinase inhibitor 1A

1 protein, 228 patents, 0 drugs, 0 trials, 13,295 NIH grants and 36,907 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolCDKN1AHGNC
Namecyclin dependent kinase inhibitor 1AHGNC
NCBI Gene ID1026NCBI Gene
HGNC IDHGNC:1784HGNC
EnsemblENSG00000124762NCBI Gene
AliasesCAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21, p21CIP1, p21Cip1/Waf1NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P38936Cyclin-dependent kinase inhibitor 116413Ensembl, GeneID, HGNCUniProt

Patents 228

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-191136P38936Espacenet
EP 4641201 A22025-10-29806P38936Espacenet
EP 4641202 A22025-10-294420P38936Espacenet
WO 2025219463 A12025-10-232P38936Espacenet
JP 2025517969 A2025-06-12806P38936Espacenet
JP 2025517970 A2025-06-121136P38936Espacenet
US 12280021 B22025-04-2258P38936Espacenet
US 12269793 B22025-04-0858P38936Espacenet
JP 2025032204 A2025-03-1126174P38936Espacenet
JP 2025032204 A2025-03-1126175P38936Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 13295

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant2512,025NIH's project files
P30CA008748Cancer Center Support Grant1322,025NIH's project files
P30CA016056Roswell Park Cancer Center Support Grant662,025NIH's project files
P01AG062413Targeting Cellular Senescence to Extend Healthspan652,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)572,025NIH's project files
P30CA016058Cancer Center Support Grant532,025NIH's project files
P30CA010815Consolidated Basic Cancer Research Program412,025NIH's project files
P30CA046934University of Colorado Cancer Center Support Grant412,025NIH's project files
P30CA068485Cancer Center Support Grant412,025NIH's project files
R37AG013925Effect of Aging on Preadipocyte Differentiation412,025NIH's project files

Papers 36907

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42823180PubTator, text miningPubMed
42821135PubTator, text miningPubMed
42821040PubTator, text miningPubMed
42797461PubTator, text miningPubMed
42797373PubTator, text miningPubMed
42797334PubTator, text miningPubMed
42795384PubTator, text miningPubMed
42792719PubTator, text miningPubMed
42792657PubTator, text miningPubMed
42781707PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license