Gene · 10273
STUB1: STIP1 homology and U-box containing protein 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. STUB1: STIP1 homology and U-box containing protein 1. Genes, record 10273. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10273
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q9UNE7 | E3 ubiquitin-protein ligase CHIP | 303 | 27 | Ensembl, GeneID, HGNC |
Source UniProt
Patents45
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026514437 A | 2026-05-11 | 10 | Q9UNE7 | Espacenet |
| JP 2026507518 A | 2026-03-04 | 145 | Q9UNE7 | Espacenet |
| EP 4687954 A2 | 2026-02-11 | 10 | Q9UNE7 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 65637 | Q9UNE7 | Espacenet |
| EP 4665771 A1 | 2025-12-24 | 145 | Q9UNE7 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 457 | Q9UNE7 | Espacenet |
| EP 4580648 A2 | 2025-07-09 | 3 | Q9UNE7 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 457 | Q9UNE7 | Espacenet |
| WO 2025101862 A1 | 2025-05-15 | 7 | Q9UNE7 | Espacenet |
| US 11860162 B2 | 2024-01-02 | 1554 | Q9UNE7 | Espacenet |
1 to 10 of 45
See all 45 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,081
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | STUB1 papers | Newest fiscal year |
|---|---|---|---|
| R01NS059690 | Molecular Chaperones and Small Molecules | 13 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 6 | 2025 |
| P30DK026743 | UCSF Liver Center | 5 | 2025 |
| P30CA010815 | Consolidated Basic Cancer Research Program | 4 | 2025 |
| R01NS073899 | The hsp90 Cochaperone FKBP51 Regulates tau Structure and Function | 4 | 2025 |
| R35GM119544 | Investigation into protein quality control pathways in Dictyostelium discoideum | 4 | 2025 |
| P30CA023168 | Cancer Center Support Grant | 3 | 2025 |
| P30CA093373 | Cancer Center Support Grant P30 | 3 | 2025 |
| P30CA125123 | Baylor College of Medicine Cancer Center - Cancer Center Support Grant | 3 | 2025 |
| R01GM094231 | COMPUTATIONAL TOOLS FOR MASS SPECTROMETRY-BASED INTERACTOME DATA | 3 | 2025 |
1 to 10 of 1,081Source NIH's project files
See all 1,081 nih grantsPapers1,745
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| ATXN8OS Intermediate Expansion Acts as a Genetic Modifier in Spinocerebellar Ataxia Type 48 (SCA48/STUB1). | Mov Disord | 2026 | 42768770 | PubTator, text mining | PubMed |
| Mitochondrial Dysfunction in Digenic TBP/STUB1 Spinocerebellar Ataxia. | Mov Disord Clin Pract | 2026 | 42768734 | PubTator, text mining | PubMed |
| Chaperone-assisted selective autophagy (CASA) in polyglutamine-related diseases: From mechanisms to therapeutic perspectives. | J Huntingtons Dis | 2026 | 42690709 | PubTator, text mining | PubMed |
| Targeting ADAR stability: a novel approach to combat glioblastoma. | Front Oncol | 2026 | 42625588 | PubTator, text mining | PubMed |
| AURKB-mediated phosphorylation of metabolic enzyme CD73 drives immune suppression and renal cell carcinoma progression. | Cell Death Differ | 2026 | 42613426 | PubTator, text mining | PubMed |
Corrigendum to "Hyperoside impairs mitochondrial respiration in chronic myeloid leukemia by promoting STUB1-mediated ubiquitination and degradation of NOX4" [Toxicology and Applied Pharmacology 511 (2026) 117795]. | Toxicol Appl Pharmacol | 2026 | 42607845 | PubTator, text mining | PubMed |
| FGD5 regulates PGK1 ubiquitination to synergize with 2-deoxy-D-glucose in pancreatic ductal adenocarcinoma. | Oncogene | 2026 | 42567886 | PubTator, text mining | PubMed |
| Domain-dependent uncoupling of the co-chaperone and E3 ubiquitin ligase CHIP underlies heterogeneity in spinocerebellar ataxia 48. | J Biol Chem | 2026 | 42567515 | PubTator, text mining | PubMed |
| A de novo designed enzyme for photo-proximity labeling of E3 ligase neighborhoods in live cells. | bioRxiv | 2026 | 42538903 | PubTator, text mining | PubMed |
| Arsenic trioxide promotes a glue‑like interaction to drive STUB1-mediated NPM-ALK degradation in ALK+ ALCL. | Exp Hematol Oncol | 2026 | 42533362 | PubTator, text mining | PubMed |
1 to 10 of 1,745
See all 1,745 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/10273
GET https://conductscience.org/api/genes/v1/10273/patents?page=2