Gene · 10278
EFS: embryonal Fyn-associated substrate
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. EFS: embryonal Fyn-associated substrate. Genes, record 10278. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10278
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| O43281 | Embryonal Fyn-associated substrate | 561 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents17
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 44915 | O43281 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 364 | O43281 | Espacenet |
| EP 4583897 A1 | 2025-07-16 | 4 | O43281 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 364 | O43281 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 27153 | O43281 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 130124 | O43281 | Espacenet |
| JP 2019054813 A | 2019-04-11 | 225350 | O43281 | Espacenet |
| JP 2017121241 A | 2017-07-13 | 225350 | O43281 | Espacenet |
| JP 2015516143 A | 2015-06-08 | 225350 | O43281 | Espacenet |
| EP 2607900 A1 | 2013-06-26 | 1049 | O43281 | Espacenet |
1 to 10 of 17
See all 17 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants842
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | EFS papers | Newest fiscal year |
|---|---|---|---|
| P30CA006927 | Comprehensive Cancer Center Program at Fox Chase | 14 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 6 | 2025 |
| P30CA045508 | CSHL Cancer Center Support Grant | 6 | 2025 |
| R35GM118174 | Mechanistic Investigation of RNA-Mediated Gene Regulation and Immunity | 6 | 2025 |
| P01CA013106 | Targeting Transcription and Splicing in Cancer | 4 | 2025 |
| P30CA014051 | Cancer Center Support (Core) Grant | 4 | 2025 |
| P30CA021765 | Cancer Center Support Grant (CCSG) | 4 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 3 | 2025 |
| R35GM118160 | CRISPR Capture, Destroy, and Counter-Attack Mechanisms | 3 | 2025 |
| R35GM137883 | Generation of DNA memory by bacterial CRISPR-Cas9 systems | 3 | 2025 |
1 to 10 of 842Source NIH's project files
See all 842 nih grantsPapers1,523
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Inhibiting TNAP Attenuates the Aortic Valve Calcification and Reduces Oxidative Stress. | Cells | 2026 | 42738837 | PubTator, text mining | PubMed |
| Environmentally friendly solvents: the strategic and frontier fields of natural product extraction. | Food Chem | 2026 | 42721589 | PubTator, text mining | PubMed |
| Diverse routes to Cas3 activation in type I CRISPR-Cas immunity. | Cell Rep | 2026 | 42721033 | PubTator, text mining | PubMed |
| Recruitment of Cas3 enables DNA cleavage by the type I-A CRISPR-Cas system of Saccharolobus islandicus. | Cell Rep | 2026 | 42570236 | PubTator, text mining | PubMed |
| CRISPR-Cas systems as precision antimicrobials: Reversing the tide of antimicrobial resistance. | Virus Res | 2026 | 42551559 | PubTator, text mining | PubMed |
| Synergistic Inhibition of Colorectal Cancer Growth by Combined PI3K and COX-2 Blockade in Cell Lines and Patient-Derived Organoids. | Pharmaceutics | 2026 | 42357299 | PubTator, text mining | PubMed |
| Gigabase-scale deletion scanning of the human genome. | bioRxiv | 2026 | 42282737 | PubTator, text mining | PubMed |
| The effects of external electric fields on proteins. | Chem Soc Rev | 2026 | 41995174 | PubTator, text mining | PubMed |
Correction: Sarman, E.; Asci, H. Cellular Anti-Apoptotic Effects of Dapagliflozin in Methotrexate-Induced Liver Toxicity: Bax/Bcl-2/Cyt-C/Cas-9/Cas-3 Signaling Pathway. Int. J. Mol. Sci. 2026, 27, 2110. | Int J Mol Sci | 2026 | 41977518 | PubTator, text mining | PubMed |
| Targeting mitochondrial apoptosis in septic lung injury: protective potential of omega-3 fatty acids. | Apoptosis | 2026 | 41894027 | PubTator, text mining | PubMed |
1 to 10 of 1,523
See all 1,523 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/10278
GET https://conductscience.org/api/genes/v1/10278/patents