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Gene · 10280

Papers1,549

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Hallucinogenic Therapy in Alzheimer's Disease targeting Mitochondria-Associated Membranes.Neuroscience202641707907PubTator, text miningPubMed
pH-Responsive Resveratrol Liposomes Targeting Sigma1 Receptor Attenuate Renal Fibrosis by Remodeling the Renal Microenvironment.Mol Pharm202641660892PubTator, text miningPubMed
SIRT3-mediated mitophagy by deacetylating ATP5F1A involved in the protective effects of SIGMAR1/Sigma-1 receptor against ferroptosis and microvascular hyperpermeability in lipopolysaccharide-induced acute lung injury.
Autophagy202641655128PubTator, text miningPubMed
Discovery of 3-indolealkylamines as novel dual-target σ1R/H3R ligands with potent analgesia.Eur J Med Chem202641616703PubTator, text miningPubMed
The genetics of autosomal recessive ALS: a review of the common forms and their phenotypes.Amyotroph Lateral Scler Frontotemporal Degener202641592170PubTator, text miningPubMed
Mitochondria-endoplasmic reticulum contact sites in hepatocytic senescence.Cell Mol Biol Lett202641521283PubTator, text miningPubMed
Organelle-specific regulation of ferroptosis.Biol Direct202641484993PubTator, text miningPubMed
Genome-wide meta-analysis with 2,206,440 individuals identifies 322 novel risk loci for obesity.Int J Obes (Lond)202641398384PubTator, text miningPubMed
SIGMAR1 gene-related neuromuscular disorders - what do we know?Neurol Neurochir Pol202641334667PubTator, text miningPubMed
Effects of apigenin, hesperidin and their combinations on different physiopathological pathways in 5-fluorouracil-induced pulmonary damage.Arch Physiol Biochem202640654296PubTator, text miningPubMed
Genomic Insights into Oral Cancer Highlight Mutant SIGMAR1 as a Critical Target to Overcome Chemoresistance.Biochem Genet202640257692PubTator, text miningPubMed
Role of extracellular vesicle-mediated neurodegeneration in substance use disorders.Curr Opin Physiol202542267144PubTator, text miningPubMed
Sigma receptors and mitochondria-associated ER membranes are converging therapeutic targets for Alzheimer's disease.Front Neurosci202541488323PubTator, text miningPubMed
SigmaR1 is an auxiliary translocon factor with lipid-binding activity that regulates protein and lipid droplet homeostasis.Nat Commun202541476177PubTator, text miningPubMed
Analysis of blasting characteristics in interbedded rock masses based on particle expansion method.Sci Rep202541454031PubTator, text miningPubMed
Sigma1R restores mitochondrial energy metabolism via the IRE1α/XBP1 pathway.Sci Rep202541422123PubTator, text miningPubMed
The sigma-1 receptor as a neurohomeostatic decision hub for GABARAP-mediated receptor trafficking and macroautophagy.Front Mol Biosci202541244707PubTator, text miningPubMed
The Sigma-1 Gene as a Prognostic Marker in Chemotherapy-Treated Breast Cancer-Antagonists' Synergism With Paclitaxel In Vitro.Cancer Med202541223123PubTator, text miningPubMed
Investigation of the mechanism by which sigma-1 receptor protein mediates the IRE1-XBP-1s pathway to alleviate cerebral ischemia-reperfusion injury.Eur J Med Res202541163082PubTator, text miningPubMed
Discovery and proof-of-concept study of a novel highly selective sigma-1 receptor agonist for antipsychotic drug development.Acta Pharm Sin B202541132847PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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