ConductScience.org, home

Library / Genes

CDKN2A: cyclin dependent kinase inhibitor 2A

2 proteins, 229 patents, 0 drugs, 0 trials, 17,828 NIH grants and 66,498 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolCDKN2AHGNC
Namecyclin dependent kinase inhibitor 2AHGNC
NCBI Gene ID1029NCBI Gene
HGNC IDHGNC:1787HGNC
EnsemblENSG00000147889NCBI Gene
AliasesARF, CAI2, CDK4I, CDKN2, CMM2, INK4, INK4A, INK4a, MLM, MTS-1, MTS1, P14, P14ARF, P16, P16-INK4A, P16INK4, P16INK4A, P19, P19ARF, TP16, p14, p14ARF, p16, p16INK4a, p19, p19ArfNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 2

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P42771Cyclin-dependent kinase inhibitor 2A1565Ensembl, GeneID, HGNCUniProt
Q8N726Tumor suppressor ARF1320Ensembl, GeneID, HGNCUniProt

Patents 229

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026102714 A2026-06-231P42771Espacenet
EP 4650780 A22025-11-1915533Q8N726Espacenet
EP 4650780 A22025-11-194472P42771Espacenet
US 12466828 B22025-11-111P42771Espacenet
EP 4640849 A22025-10-29593P42771Espacenet
EP 4641201 A22025-10-2918584Q8N726Espacenet
EP 4641201 A22025-10-294017P42771Espacenet
JP 2025159357 A2025-10-201P42771Espacenet
JP 2025147176 A2025-10-062553P42771Espacenet
JP 2025147176 A2025-10-062560Q8N726Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 17828

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant7922,025NIH's project files
P30CA016672Cancer Center Support Grant6992,025NIH's project files
P30CA006973Regional Oncology Research Center1892,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)1462,025NIH's project files
P30CA016058Cancer Center Support Grant1332,025NIH's project files
P30CA006927Comprehensive Cancer Center Program at Fox Chase1072,025NIH's project files
P30CA016086Cancer Center Support Grant1062,025NIH's project files
P30CA046592University of Michigan Rogel Cancer Center Support Grant 2023-20281022,025NIH's project files
P30ES010126UNC Center for Environmental Health and Susceptibility962,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award932,025NIH's project files

Papers 66498

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42827450PubTator, text miningPubMed
42826567PubTator, text miningPubMed
42826333PubTator, text miningPubMed
42824253PubTator, text miningPubMed
42823758PubTator, text miningPubMed
42819076PubTator, text miningPubMed
42817222PubTator, text miningPubMed
42816143PubTator, text miningPubMed
42815568PubTator, text miningPubMed
42815556PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license