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Gene · 10298

Papers1,639

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Targeting PAK1 or PAK4 Uncovers Different Mechanisms of Vascular Reprogramming in Pancreatic Cancer.Cells202541294859PubTator, text miningPubMed
P21-activated kinase 4: a potent oncogene, molecular mechanisms and opportunities for targeted therapy.Cancer Cell Int202541250149PubTator, text miningPubMed
Lower early-stage rectal cancer surgical approaches: therapeutic options and cancer biomarker alterations.Front Surg202541089440PubTator, text miningPubMed
Author Correction: PAK4 phosphorylates and inhibits AMPKα to control glucose uptake.Nat Commun202541083498PubTator, text miningPubMed
aMulti-target in silico profiling of silymarin derivatives against oncogenic pathways: Integration of docking, DFT, ADMET, and molecular dynamics.Biochem Biophys Res Commun202541033116PubTator, text miningPubMed
Corrigendum to "PAK4 inhibition significantly potentiates gemcitabine activity in PDAC cells via inhibition of Wnt/β-catenin, p-ERK/MAPK and p-AKT/PI3K pathways" [Biochemistry and Biophysics Reports, (35), September 2023, 1-8 / 101544].
Biochem Biophys Rep202540937331PubTator, text miningPubMed
Mushroom bodies tiny regulates Sidekick localization to tricellular adherens junctions.Development202540888741PubTator, text miningPubMed
PAK4 phosphorylates and stabilizes MYC to promote acute myeloid leukemia.Cell Insight202540861012PubTator, text miningPubMed
A multilevel genomic approach to uncover causal connections between CPFE and lung cancer subtypes: A two-sample Mendelian randomization study.Medicine (Baltimore)202540859573PubTator, text miningPubMed
Multi-omics analysis reveals RNA polymerase II degradation as a novel mechanism of PF-3758309's anti-tumor activity.Cell Death Discov202540854914PubTator, text miningPubMed
Mechanism and cellular actions of the potent AMPK inhibitor BAY-3827.Sci Adv202540845097PubTator, text miningPubMed
RHOV is a Detachment-Responsive Rho GTPase Necessary for Ovarian Cancer Peritoneal Metastasis.bioRxiv202540832333PubTator, text miningPubMed
MSN/STAT3 drives cancer stemness and chemoresistance via IL-6/LPAR1 ligand receptor complex in triple-negative breast cancer.Breast Cancer Res202540696387PubTator, text miningPubMed
LncRNA NEAT1 promotes epithelial-mesenchymal transition in nasal polyp cells via the miR-199-3p/PAK4 axis.Front Immunol202540661947PubTator, text miningPubMed
Chemoenzymatic Synthesis and in Vitro Selection of De Novo Thiazole-Containing Macrocyclic Peptides.Chemistry202540542492PubTator, text miningPubMed
DeepDTAGen: a multitask deep learning framework for drug-target affinity prediction and target-aware drugs generation.Nat Commun202540447614PubTator, text miningPubMed
Molecular Characterization and Clinical Outcomes of Pancreatic Neuroendocrine Neoplasms Harboring PAK4-NAMPT Alterations.JCO Oncol Adv202540330142PubTator, text miningPubMed
Red blood cell-tumor cell interactions promote tumor cell progression.J Exp Clin Cancer Res202540301999PubTator, text miningPubMed
Migrasomes as intercellular messengers: potential in the pathological mechanism, diagnosis and treatment of clinical diseases.J Nanobiotechnology202540254563PubTator, text miningPubMed
Retraction Note: PAK4, a target of miR-9-5p, promotes cell proliferation and inhibits apoptosis in colorectal cancer.Cell Mol Biol Lett202540240952PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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