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CDKN2B: cyclin dependent kinase inhibitor 2B

1 protein, 43 patents, 0 drugs, 0 trials, 6,694 NIH grants and 12,901 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolCDKN2BHGNC
Namecyclin dependent kinase inhibitor 2BHGNC
NCBI Gene ID1030NCBI Gene
HGNC IDHGNC:1788HGNC
EnsemblENSG00000147883NCBI Gene
AliasesCDK4I, INK4B, MTS2, P15, TP15, p15INK4bNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P42772Cyclin-dependent kinase 4 inhibitor B1380Ensembl, GeneID, HGNCUniProt

Patents 43

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2024123008 A2024-09-105815P42772Espacenet
US 11726090 B22023-08-153P42772Espacenet
US 11708396 B22023-07-252442P42772Espacenet
WO 2023022218 A2023-02-2323P42772Espacenet
US 11446398 B22022-09-2021380P42772Espacenet
JP 2022524081 A2022-04-27124351P42772Espacenet
US 11078247 B22021-08-031961P42772Espacenet
US 10767162 B22020-09-0894P42772Espacenet
US 10501513 B22019-12-105815P42772Espacenet
JP 2018183181 A2018-11-227426P42772Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 6694

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant1602,025NIH's project files
P30CA016672Cancer Center Support Grant942,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)392,025NIH's project files
P30CA006973Regional Oncology Research Center322,025NIH's project files
P30DK063491Diabetes Research Center (DRC)292,025NIH's project files
P30CA015083Mayo Clinic Comprehensive Cancer Center Support Grant282,025NIH's project files
P30CA016058Cancer Center Support Grant222,025NIH's project files
P50CA097257Brain Tumor SPORE Grant212,025NIH's project files
P30EY014104P30 Core Grant for Vision Research202,025NIH's project files
P30CA006927Comprehensive Cancer Center Program at Fox Chase192,025NIH's project files

Papers 12901

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42810841PubTator, text miningPubMed
42777114PubTator, text miningPubMed
42758366PubTator, text miningPubMed
42754232PubTator, text miningPubMed
42754173PubTator, text miningPubMed
42724192PubTator, text miningPubMed
42705320PubTator, text miningPubMed
42700740PubTator, text miningPubMed
42699092PubTator, text miningPubMed
42671146PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license