Gene · 1031
CDKN2C: cyclin dependent kinase inhibitor 2C
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. CDKN2C: cyclin dependent kinase inhibitor 2C. Genes, record 1031. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1031
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P42773 | Cyclin-dependent kinase 4 inhibitor C | 168 | 6 | Ensembl, GeneID, HGNC |
Source UniProt
Patents82
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4650780 A2 | 2025-11-19 | 2106 | P42773 | Espacenet |
| EP 4641202 A2 | 2025-10-29 | 4549 | P42773 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 2106 | P42773 | Espacenet |
| KR 1020250017231 A | 2025-02-04 | 4549 | P42773 | Espacenet |
| JP 2024123008 A | 2024-09-10 | 5818 | P42773 | Espacenet |
| JP 2024123008 A | 2024-09-10 | 5819 | P42773 | Espacenet |
| JP 2024123008 A | 2024-09-10 | 5820 | P42773 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 21382 | P42773 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 21383 | P42773 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 21384 | P42773 | Espacenet |
1 to 10 of 82
See all 82 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,684
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | CDKN2C papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 39 | 2025 |
| P30CA021765 | Cancer Center Support Grant (CCSG) | 27 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 22 | 2025 |
| P01CA096832 | NORMAL & NEOPLASTIC GROWTH IN THE BRAIN | 21 | 2025 |
| P30CA016058 | Cancer Center Support Grant | 8 | 2025 |
| P30CA016056 | Roswell Park Cancer Center Support Grant | 7 | 2025 |
| P01CA155258 | Integrative Oncogenomics of Multiple Myeloma | 5 | 2025 |
| P30CA015083 | Mayo Clinic Comprehensive Cancer Center Support Grant | 5 | 2025 |
| P30CA046934 | University of Colorado Cancer Center Support Grant | 5 | 2025 |
| P30CA125123 | Baylor College of Medicine Cancer Center - Cancer Center Support Grant | 5 | 2025 |
1 to 10 of 1,684Source NIH's project files
See all 1,684 nih grantsPapers2,553
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Age-Specific Transcriptomic Signatures for Classification of Progression-Free Survival Outcomes in Luminal A Breast Cancer: An Integrative Machine Learning Approach. | Biology (Basel) | 2026 | 42510705 | PubTator, text mining | PubMed |
| CRISPR/Cas9-Mediated Gene Knockout Reveals a Nonredundant Role for p16INK4A in Controlling TCR-Dependent and Independent CD8 T Cell Expansion. | Eur J Immunol | 2026 | 42345443 | PubTator, text mining | PubMed |
| Cancer-associated adipocytes confer CDK4/6 inhibitor resistance in ER+ breast cancer through an IL-6/STAT3/SREBF2 axis coupled with cholesterol metabolism and cell cycle reprogramming. | Int J Biol Sci | 2026 | 42328452 | PubTator, text mining | PubMed |
| EBV (LMP1) enhances cisplatin resistance by enhancing degradation of interferon regulatory factor 3. | Cell Commun Signal | 2026 | 42141449 | PubTator, text mining | PubMed |
| Short-Duration HIPEC-Mimetic Mithramycin A Exposure Induces Durable Transcriptional Remodeling Involving Chromatin Regulatory Networks in Colorectal Cancer Models. | Int J Mol Sci | 2026 | 42074218 | PubTator, text mining | PubMed |
| Ubiquitin Ligase RNF149 Promotes Head and Neck Cancer Growth via Downregulation of CDKN2C. | Anticancer Res | 2026 | 42049330 | PubTator, text mining | PubMed |
| CRISPR Screens Reveal Epstein-Barr Virus-activated JunB as a Key Lymphoblastoid B cell Dependency Factor that Represses Cyclin Dependent Kinase Inhibitor P18INK4c. | bioRxiv | 2026 | 41959378 | PubTator, text mining | PubMed |
| Protein arginine methyltransferases in cancer: mechanisms, functions, and therapeutic opportunities. | J Biomed Sci | 2026 | 41928257 | PubTator, text mining | PubMed |
| RNA N6-methyladenosine (m6A) regulates cell cycle progression in diffuse midline glioma (DMG) and confers sensitivity to FTO inhibition. | Cell Death Dis | 2026 | 41888518 | PubTator, text mining | PubMed |
| Blastoid Mantle Cell Lymphoma in the Leukemic Phase: Resolving a Morphological Dilemma Through Flow Cytometry. | Cureus | 2026 | 41869126 | PubTator, text mining | PubMed |
1 to 10 of 2,553
See all 2,553 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/1031
GET https://conductscience.org/api/genes/v1/1031/patents?page=2