Gene · 10313
RTN3: reticulon 3
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. RTN3: reticulon 3. Genes, record 10313. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/10313
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| O95197 | Reticulon-3 | 1,032 | 1 | Ensembl, GeneID, HGNC |
Source UniProt
Patents23
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 61434 | O95197 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 10235 | O95197 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 3792 | O95197 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 3792 | O95197 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 10235 | O95197 | Espacenet |
| KR 1020240173306 A | 2024-12-11 | 11 | O95197 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 72783 | O95197 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 175754 | O95197 | Espacenet |
| US 11078247 B2 | 2021-08-03 | 9854 | O95197 | Espacenet |
| KR 1020210091089 A | 2021-07-21 | 28 | O95197 | Espacenet |
1 to 10 of 23
See all 23 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants668
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | RTN3 papers | Newest fiscal year |
|---|---|---|---|
| R01AG046929 | Inhibition of BACE1 for benefiting Alzheimer's patients | 5 | 2025 |
| R01CA118953 | Improving Outcomes Assessment in Chronic Graft versus Host Disease | 5 | 2025 |
| P30CA014195 | Cancer Center Support Grant (CCSG) | 2 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 2 | 2025 |
| P30DK045735 | Yale Diabetes Research Center | 2 | 2025 |
| P30EY008126 | Core Grant in Vision Research | 2 | 2025 |
| R01DE013414 | MATRIX BASED MINERAL ENAMEL-BIOMIMETICS | 2 | 2025 |
| R35GM131681 | The diverse roles of ER-Golgi trafficking machinery in autophagy and ER quality control | 2 | 2025 |
| T32HD040686 | Pediatric Neurointensive Care and Resuscitation Research | 2 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 2 | 2025 |
1 to 10 of 668Source NIH's project files
See all 668 nih grantsPapers1,763
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Reticulon-3 in endoplasmic reticulum remodeling and cardiometabolic-fibrotic disease. | Pharmacol Res | 2026 | 42822554 | PubTator, text mining | PubMed |
| Multimodal AI and single-cell transcriptomics integrate to construct a histopathological prognostic model for bladder cancer, revealing the RTN3-glycolysis axis in chemoresistance. | Exp Hematol Oncol | 2026 | 42745263 | PubTator, text mining | PubMed |
| Retraction: Tissue specificity and regulation of the N-terminal diversity of reticulon 3. | Biochem J | 2026 | 42719941 | PubTator, text mining | PubMed |
| Shikonin inhibits bladder cancer progression by targeting deoxyribonuclease 2 to suppress reticulon 3-dependent endoplasmic reticulum autophagy. | Phytomedicine | 2026 | 42594755 | PubTator, text mining | PubMed |
Integrating Mendelian randomization, machine learning and retrospective clinical data: an exploratory analysis of the cross-disease association between CHB and PD, with a focus on eosinophil alterations. | Front Neurol | 2026 | 42494392 | PubTator, text mining | PubMed |
| Downregulation of miR-6721-5p in the serum of patients with spinal cord injury and its role in regulating microglial inflammation via targeting RTN3. | J Orthop Surg Res | 2026 | 42415078 | PubTator, text mining | PubMed |
| Unveiling ER-Phagy Receptors in Thyroid Cancer: A Combined Approach of Public Data Mining and In Vitro Validation. | Clin Med Insights Oncol | 2026 | 42312220 | PubTator, text mining | PubMed |
| Beyond Free Virions: Interconnected Secretory Pathways and Reticulon 3 (RTN3) Coordinate Extracellular Vesicle Diversity for Infectious Exosome Generation. | Biology (Basel) | 2026 | 42117840 | PubTator, text mining | PubMed |
| An autophagy-related molecule reticulon 3 functions as a novel prognostic biomarker in hepatocellular carcinoma. | Genes Dis | 2026 | 42063417 | PubTator, text mining | PubMed |
| Interactions of Silver Ions with the Hydroxyapatite-Iron Oxide Composite Surface in Liquid. | Chemphyschem | 2026 | 42018490 | PubTator, text mining | PubMed |
1 to 10 of 1,763
See all 1,763 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/10313
GET https://conductscience.org/api/genes/v1/10313/patents?page=2